This article focuses the choice and use of examples by two students of the 11th grade to prove or refute a set of statements. The use of representations of sequences and functions is also considered. The study adopts a qualitative approach and data were collected by interviews and documental gathering. The conclusions suggest most of the examples used were well-known sequences or functions. However, the students sought different purposes for the use of examples, such as understanding the conjecture, demonstrate the falsity or truthfulness of the statement and conveying a general argument. The students made a satisfactory articulation between the various types of representations but relied mostly in the cartesian graph.

Summary The emergence of bacterial resistance to different antibiotics in clinical use, together with the knowledge on the mechanisms by which bacteria resist the action of aminoglycosides, have contributed to the renewed interest in these molecules as potential antimicrobials. Here, we give an overview on natural and semisynthetic aminoglycosides and their structural features and modes of action, focusing on the structural insight underlying resistance mechanisms. Developments on carbohydrate chemistry and microarray technology are highlighted as powerful approaches toward generation of new aminoglycosides and for screening their interactions with RNAs and proteins. The link between antibiotic uptake and the human gut microbiome is also addressed, focusing on gut microbiome function and composition, antibiotic-induced alterations in host health, and antibiotic resistance. In addition, strategies to modulate human microbiome responses to antibiotics are discussed as novel approaches for aminoglycoside usage and for the effectiveness of antibiotic therapy.

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The degradation mechanisms of bonded joints between CFRP laminates and steel substrates under severe environmental conditions require more durability data and studies to increase the database and better understand their causes. Studies on bond properties of double-strap CFRP-to-steel bonded joints with two different composite materials as well as adhesive coupons subjected to freeze-thaw cycles for 10,000 h were conducted to reduce that gap. In addition, the equivalent to the number of thermal cycles and their slips induced in the CFRP laminates was replicated by an equivalent (mechanical) loading-unloading history condition imposed by a static tensile machine. The mechanical properties of the adhesive coupons and the strength capacity of the bonded joints were only slightly changed by the artificial aging. It was confirmed that the interfacial bond strength between CFRP and adhesive is critically related to the maximum shear stress and failure mode. The interfacial bond strength between adhesive and steel degraded with the aging. However, the equivalent thermal cyclic bond stress caused no detectable damage on the bond because only the interfacial elastic regime was actually mobilized, which confirmed that pure thermal cycles aging, per se, at the level imposed, have a low impact on the degradation of CFRP-to-steel bonded joints. © 2019 Elsevier Ltd

This study aims to evaluate the effect of mineral fillers on bitumen ageing. Two different bitumens and four mastics were investigated in the unaged and long-term aged states, based on different properties (consistency, rheology, fatigue resistance and ductility). Mastics stiffened less due to ageing treatment than bitumens, especially with granite filler. However, the results of the performance tests were not definitive regarding the effect of the filler. Aged bitumen showed greater fatigue resistance and higher specific energy of ductile fracture than unaged bitumen, whereas the mastics showed minor variations in the specific energy of ductile fracture with ageing treatment, which is indicative of less ageing, but the fatigue resistance decreased significantly in mastics with one of the bitumens.

Adhesively bonded joints have been widely used by engineers to solve problems in different industries. Despite recent studies which have helped with the design and application of these joints, there are still several uncertainties that justify empirical implementation in practice. One main aspect is the rigorous understanding of the performance of these joints when subjected to cyclic loading. Although the monotonic performance of adhesively bonded joints is well known, the cyclic behaviour raises several issues. Therefore, a numerical strategy based on the Distinct Element Method (DEM) was implemented in this work to mitigate the lack of knowledge about the cyclic behaviour between two materials adhesively bonded to each other. For that purpose, the single-lap pull-push test was modelled and due to the diversity of the existing cohesive models, four different bond-slip relationships and two unloading paths (with ductile or “cleavage unloading”) were considered. The results suggest that if the bond-slip relationship has an elastic stage, then the interfacial bond degradation is delayed. On the other hand, the interfacial damage of the joints with the number of cycles increases rapidly in those cases where the bond-slip relationships have no elastic stage and, at the same time, the slip accumulation is allowed. In addition, the results of two different tests available in the literature were implemented and fairly reproduced by the DEM. © 2019 Elsevier Ltd

An optical experimental procedure for evaluating the J-Integral from full-field displacement fields under dynamic loading is proposed in this work. The methodology is applied to measure the J-integral in the dynamic compressive loading of fiber-reinforced composites and to calculate the dynamic fracture toughness associated with the propagation of a kink-band. A modified J-Integral that considers inertia effects is calculated over the full-field measurements obtained by digital image correlation, for double edge-notched specimen of IM7-8552 laminates dynamically loaded in a split-Hopkinson pressure bar (SHPB). A sensibility study is conducted to address the influence of the speckle parameters. The results show good agreement with experimental observations obtained by using a different data reduction method, suggesting the existence of a rising R-curve for the studied material under dynamic loading. Furthermore, it was noticed that the inertia effect can be negligible, indicating a state of dynamic equilibrium in which quasi-static approaches may comfortably be used.

We report on measurements of the Kβ diagram, valence-to-core (VtC), and hypersatellite X-ray spectra induced in metallic Cr by photon single and double K-shell ionization. The experiment was carried out at the Stanford Synchrotron Radiation Lightsource using the seven-crystal Johann-type hard X-ray spectrometer of the beamline 6-2. For the Kβ diagram and VtC transitions, the present study confirms the line shape features observed in previous works, whereas the K h β hypersatellite transition was found to exhibit a complex spectral line shape and a characteristic low-energy shoulder. The energy shift of the hypersatellite relative to the parent diagram line was deduced from the measurements and compared with the result of extensive multiconfiguration Dirac–Fock (MCDF) calculations. A very good agreement between experiment and theory was found. The MCDF calculations were also used to compute the theoretical line shape of the hypersatellite. A satisfactory agreement was obtained between the overall shapes of the experimental and theoretical spectra, but deviations were observed on the low- and high-energy flanks of the hypersatellite line. The discrepancies were explained by chemical effects, which were not considered in the MCDF calculations performed for isolated atoms.

Our world is facing substantial economic and social challenges due to an increasing pace of technological developments. The introduction of the Internet of Things (IoT) is ushering in a fourth industrial revolution. The vision of Industry 4.0 describes a whole new approach to business operations, and especially the production industries which is characterized by a new level of socio-technical interaction. Emphasizing the importance of intangibles management, organizations have become increasingly focused on the Intellectual Capital (IC) as the main source of value creation. From a strategic point of view, IC is linked to the ability to create and apply the potential of an organizations knowledge based capabilities, and is commonly categorized into three main components: human, structural and relational capital. The industry 4.0 is changing the way we create value which requires from organizations and individuals a rethinking of what is expected or desired from the internet-connected devices. As a phenomenon of interactions and complementarities, IC can offer a possible pathway for reconfiguring business models. The contribution of this work is mainly conceptual. The aim of this paper is to explore what has been researched so far about the importance of industry 4.0 with impact in organizational value creation and how the theory of intellectual capital can help to leverage its benefits. To achieve this objective, a comprehensive review of journal articles, conference papers, books and international reports was performed

The estimation of the long-term durability of adhesively bonded interfaces between Fiber Reinforced Polymers (FRP) and concrete substrates is crucial because degradation potentiates FRP premature debonding. One of the main reasons for mistrusting the use of FRP composites is the premature debonding phenomenon, which, associated to degradation, has been preventing their widespread use. In this research work, an analytical model is proposed that introduces ageing to estimate the effects of degradation of Glass (G) FRP externally bonded to concrete. Cycles were used to experimentally accelerate ageing of beam specimens, namely, (i) salt fog cycles; (ii) wet-dry cycles with salted water; (iii) temperature cycles between −10 °C and +30 °C; and (iv) temperature cycles between +7.5 °C and +47.5 °C. Based on the experimental results obtained and a corresponding bond-slip curve, the analytical model predicts the complete debonding process between FRP composites and a substrate. Consequently, the temporal evolution of the degradation of the bonded interfaces can be calculated and compared with the initial situation prior to exposure. The effects of the environmental conditions are reported and compared. © 2018 Elsevier Ltd

This chapter provides an overview of the alpha paleobiodiversity of Angola based on the available fossil record that is limited to the sedimentary rocks, ranging in age from Precambrian to the present. The geological period with the highest paleobiodiversity in the Angolan fossil record is the Cretaceous, with more than 80{%} of the total known fossil taxa, especially marine molluscs, including ammonites as a majority among them. The vertebrates represent about 15{%} of the known fauna and about one tenth of them are species firstly described based on specimens from Angola.