In recent years, statistical data revealed a strong dynamism in terms of Research and Development (R&D) growth, of development of innovation structures and emergence of programs, and a growth in terms of industrial integration. However, the political and financial changes from 2007 at the global level revealed as well how fragile are these
outcomes in terms of sustainable development strategy, and how far dependent are from the external markets and political structures. Based on the available information and data, we will present the changes observed in recent years, and understand how the industrial integration can be achieved with clear linkages to the national innovation system and the importance of R&D policy to structure the articulation between innovation and the economic market. The challenges and potential problems can be anticipated if the social implications are also present on the policy options, and if clear technology assessment procedures are taken. When this does not occur, the probability of endogenization of innovation and R&D will become problematic. For these reasons it can be difficult to talk
about a “success story” when all these elements are not considered as a whole and are only seen through very specific angles and with very specialized approaches.

Summary The emergence of bacterial resistance to different antibiotics in clinical use, together with the knowledge on the mechanisms by which bacteria resist the action of aminoglycosides, have contributed to the renewed interest in these molecules as potential antimicrobials. Here, we give an overview on natural and semisynthetic aminoglycosides and their structural features and modes of action, focusing on the structural insight underlying resistance mechanisms. Developments on carbohydrate chemistry and microarray technology are highlighted as powerful approaches toward generation of new aminoglycosides and for screening their interactions with RNAs and proteins. The link between antibiotic uptake and the human gut microbiome is also addressed, focusing on gut microbiome function and composition, antibiotic-induced alterations in host health, and antibiotic resistance. In addition, strategies to modulate human microbiome responses to antibiotics are discussed as novel approaches for aminoglycoside usage and for the effectiveness of antibiotic therapy.

Energy storage systems (ESS) are seen as one of the main pillars for a renewable-based energy system. Selecting the most suitable and sustainable ESS for a given project is a problem that involves multiple stakeholders with quite often diverging objectives that cannot all be fulfilled by a single technology. Several studies are available that tackle this problem applying multi-criteria decision analysis (MCDA). However, these use very different Multi-Attribute Decision Making (MADM) approaches, criteria and goals for decision support, why their results are difficult to compare or to reproduce. This work presents a review of existing MCDA-literature using MADM as a tool for sustainability evaluation of grid-tied ESS. Available studies are summarized, the goals, used MADM methods, and quantification of criteria are analyzed and discussed to provide tentative recommendations. The reviewed studies cover multiple technologies ranging from electrochemical, mechanical or electric ESS. Considered criteria are mainly structured around technology, economy, society, and environment, comprising a high number of individual sub-criteria. The aggregation of these criteria is mainly realized through the Analytic Hierarchy Process (AHP) in combination with a wide set of other methods. The quantification of various criteria is often based on different literature sources wherein context-free data for cost, and environmental impacts are used, leading in some cases to inconsistent comparisons in the assessments. Only in a few cases, assessments are linked to specific application requirements, which are decisive factors for the design of an ESS. A minority of the reviewed works include a representative set of decision-makers in their approaches, wherein the number or type of participants is often not communicated transparently. Therefore, most of the studies are considered to have a limited orientation towards practical decision making, but they provide valuable information regarding MADM method development.

The results of a series of experiments on four reinforced concrete flat slab specimens with shear studs and a control specimen without any shear reinforcement are presented. The specimens were tested under constant gravity loads and reversed horizontal cyclic displacements. The main test variables were the applied gravity load and the number of perimeters of studs. One of the specimens was tested in two phases to study the postearthquake behavior. Results showed a considerable improvement of the deformation capacity of specimens with studs compared to the reference specimen. In agreement with previous research, increasing the applied gravity shear ratio resulted in a lower experimental drift capacity. It is shown that a better explanation of the observed ultimate drifts can be made by considering also the flexural capacity and the extent of shear reinforcement. The specimen tested in two phases exhibited considerable residual capacity, even after severe horizontal loading.

In this paper, three metaheuristics are investigated to optimize RF Integrated Inductors; namely Differential Evolution (DE) from the field of evolutionary computation, Gravitational Search Algorithm (GSA) based on the law of gravity and mass interactions and Particle Swarm Optimization (PSO) inspired by swarm behaviors in nature. A particular interest is given to the optimization of RF Integrated Inductors. Performances in terms of optimum quality and computing time of the metaheuristics are checked via three test functions and one application that consist of optimizing performances of characterize integrated inductors based on the double$π$-model.

The results of a series of experiments on four reinforced concrete flat slab specimens with shear studs and a control specimen without any shear reinforcement are presented. The specimens were tested under constant gravity loads and reversed horizontal cyclic displacements. The main test variables were the applied gravity load and the number of perimeters of studs. One of the specimens was tested in two phases to study the postearthquake behavior. Results showed a considerable improvement of the deformation capacity of specimens with studs compared to the reference specimen. In agreement with previous research, increasing the applied gravity shear ratio resulted in a lower experimental drift capacity. It is shown that a better explanation of the observed ultimate drifts can be made by considering also the flexural capacity and the extent of shear reinforcement. The specimen tested in two phases exhibited considerable residual capacity, even after severe horizontal loading.

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This article presents a synthesis of Palaeozoic and Mesozoic fossil tetrapods from Greenland, including an updated review of the holotypes and a new photographic record of the main specimens. All fossil tetrapods found are from East Greenland, with at least 30 different known taxa: five stem tetrapods (Acanthostega gunnari, Ichthyostega eigili, I. stensioi, I. watsoni, and Ymeria denticulata) from the Late Devonian of the Aina Dal and Britta Dal Formations; four temnospondyl amphibians (Aquiloniferus kochi, Selenocara groenlandica, Stoschiosaurus nielseni, and Tupilakosaurus heilmani) from the Early Triassic of the Wordie Creek Group; two temnospondyls (Cyclotosaurus naraserluki and Gerrothorax cf. pulcherrimus), one testudinatan (cf. Proganochelys), two stagonolepids (Aetosaurus ferratus and Paratypothorax andressorum), the eudimorphodontid Arcticodactylus, undetermined archosaurs (phytosaurs and both sauropodomorph and theropod dinosaurs), the cynodont Mitredon cromptoni, and three mammals (Haramiyavia clemmenseni, Kuehneotherium, and cf. ?Brachyzostrodon), from the Late Triassic of the Fleming
Fjord Formation; one plesiosaur from the Early Jurassic of the Kap Stewart Formation; one plesiosaur and one ichthyosaur from the Late Jurassic of the Kap Leslie Formation, plus a previously unreported Late Jurassic plesiosaur from Kronprins Christian Land. Moreover, fossil tetrapod trackways are known from the Late Carboniferous (morphotype Limnopus) of the Mesters Vig Formation and at least four different morphologies (such as the crocodylomorph Brachychirotherium, the auropodomorph Eosauropus and Evazoum, and the theropodian Grallator) associated to archosaurian trackmakers are known from the Late Triassic of the Fleming Fjord Formation. The presence of rich fossiliferous tetrapod sites in East Greenland is linked to the presence of well-exposed continental and shallow marine deposits with most finds in terrestrial deposits from the Late Devonian and the Late Triassic.

Approaching the topic of robotics-work relation in a general and international context enables the possibility to know more about the impacts in different sectors. In this book the main discussion themes are followed in order to understand which the main dimensions are included in such debate. In that way, it becomes possible to understand the possible answers and available alternatives.
The book follows the themes of relation between employment and technology, the automation as rationalization process and robotics as a technology reference. The other topics are the emergence of ethical, legal and social aspects of this technology, the development that can be perceived in the case of Portugal, and the conclusions about the limits and perspectives of new robotic developments.
This edition has empirical information on the Portuguese case and also includes data from the main resources of the global debate on this issue: the new developments of automation and its relation with the work content and employment.
The author underlined the importance of the contribute that he got from the discussions at the ITAS Working Group on Robotics Technology Assessment, and at the ITAS Research Group on Technology and Work, in Germany, and at the Observatory of Technology Assessment at CICS.NOVA in Portugal. The book is include in a series supported by the Portuguese-American Foundation for Development (FLAD) and was published by Glaciar.

Nuclear Inst. and Methods in Physics Research, B, 408 (2017) 100-102. doi:10.1016/j.nimb.2017.04.015