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Main research topics:

1) The functional and structural characterization of a megaDalton complex, the Cellulosome, present in some anaerobic bacteria and fungi. Read more

Related financed projects

  • as PI: PTDC/QUI-BIQ/100359/2008, PTDC/QUI/68286/2006 and PTDC/BBB-BEP/0869/2014
  • as member of research team: PTDC/BIA-MIC/5947/2014, EXPL/BBB-BEP/0506/2012, PTDC/QUI-QUI/112537/2009, PTDC/BIA-PRO/103980/2008 and POCI/PPCDT/BIA-PRO/59118/2004

2) Structural characterization in different biological systems.

member of research team of projects: 

  • PTDC/BIA-MIB/31730/2017 “Glycan-human microbe interaction: glycan diversity and recognition in the human gut with impact on health and nutrition",
  • PTDC/DTP-FTO/1981/2014 "ACTONP53: Targeting p53 family proteins: on the route to new anticancer agents", 
  • "DeCellMab: Trifunctional antibodies and dendritic cell-based technologies: a combined approach to cancer immunotherapy" (Bluepharma/UCoimbra Award 2013), and 
  • “Antibody Engineering for the Treatment of Breast Cancer” (Santander-Totta/NOVA Award 2012) 

3) Study of protein crystal growth and phasing using nanoparticles and/or ionic liquid compounds.

member of research team of project PTDC/BBB-BEP/3058/2012 “Novel approaches for protein crystallization using ionic liquid-based systems"

Lysozyme crystal grown from a neat ionic liquid (IL) solution with the IL cation and anion incorporated in the structure.

Peer-reviewing in:

  • Chemical Physics Letters
  • JBIC
  • Crystal Growth & Design
  • Journal of Applied Crystallography
  • Acta Crystallographica F (Structural Biology and Crystallization Communications Online)