Os sistemas de memória transacional distribuída atuais recorrem essencialmente à distribuição ou à replicação total para distribuir os seus dados pelos múltiplos nós do sistema. No entanto, estas estratégias de replicação de dados apresentam limitações. A distribuição não oferece tolerância a falhas e a replicação total limita a capacidade de armazenamento do sistema. Nesse contexto, a replicação parcial de dados surge como uma solução intermédia, que combina o melhor das duas anteriores com o intuito de mitigar as suas desvantagens. Esta estratégia tem sido explorada no contexto das bases de dados distribuídas, mas tem sido pouco abordada no contexto da memória transacional e, tanto quanto sabemos, nunca antes tinha sido incorporada num sistema de memória transacional distribuída para uma linguagem de propósito geral. Assim, neste artigo propomos e avaliamos uma infraestrutura para replicação parcial de dados para programas Java bytecode, que foi desenvolvida com base num sistema já existente de memória transacional distribuída. A modularidade da infraestrutura que apresentamos permite a implementação de múltiplos algoritmos e, por conseguinte, avaliar em que contextos de utilização (workloads, número de nós, etc.) a replicação parcial se apresenta como uma alternativa viável a outras estratégias de replicação de dados.

The present paper presents a physical prototype that simulates the response of a single degree of freedom dynamic system, equipped with a novel semi-active vibration control device. This device comprises two superelastic NiTi elements working in phase opposition and aims to prevent deck unseating in simply supported bridges, during a seismic excitation. The special design of this device allows to avoid problems related to stress–relaxation phenomena and material degradation because of cyclic loading that have been observed in similar passive dissipation devices. The proposed design uses a strategy that permits the continuous adapting of the accumulated stress in the NiTi wires, on the basis of the response of the device to external excitations. Although unloaded, the NiTi elements remain strain/stress free, preventing stress–relaxation phenomena. With the occurrence of a dynamic excitation, a cumulative strain/stress process in the superelastic wires is initiated, enabling higher martensite transformation ratios and therefore increasing the damping capacities of the system while keeping the stresses in the wires inside a narrower superelastic window. The strain/stress accumulation in the superelastic wires is a direct result of the motion of the structure itself, with no need for external energy input.

The use of agar-based biomaterials for the development of emerging areas, such as tissue engineering or ‘smart materials’ production has recently gained great interest. Understanding how these gel-forming polysaccharides self-organise in aqueous media and how these associations can be tuned to meet the specific needs of each application is thus of great relevance. As an extension of previous pioneering research concerning the application of the microwave-assisted extraction (MAE) technique in the recovery of native (NA) and alkali-modified (AA) agars, this article focuses on the different molecular assemblies assumed by these novel NA and AA when using different MAE routes. The molecular architectures in dilute (5, 10, 50 and 100 mg mL
1) and concentrated (1.5% (w/w)) aqueous media were imaged by AFM and cryoSEM, respectively. Relevant structural and physicochemical properties were investigated to support the microscopic data. Different extraction routes led to polysaccharides with unique properties, which in turn resulted in different molecular assemblies. Even at 5 mg mL
1, AFM images included individual fibers, cyclic segments, aggregates and local networks. At higher polymer concentrations, the structures further aggregated forming multilayer polymeric networks for AA. The more compact and denser 3D networks of AA, imaged by cryoSEM, and their higher resistance to large deformations matched the 2D-shapes observed by AFM. Depending on the nature of the AA chains, homogeneous or heterogeneous growth of assemblies was seen during network formation. The obtained results support well the view of double helix formation followed by intensive double helix association proposed for agar gelation.

A new taxon of diplodocid sauropod, Kaatedocus siberi gen. et sp. nov., is recognized based on well-preserved cervical vertebrae and skull from the Morrison Formation (Kimmeridgian, Late Jurassic) of northern Wyoming, USA. A phylogenetic analysis places it inside Diplodocinae (Sauropoda: Flagellicaudata: Diplodocidae), as a sister taxon to a clade uniting Tornieria africana and the classical diplodocines Barosaurus lentus and Diplodocus. The taxon is diagnosed by a unique combination of plesiomorphic and derived traits, as well as the following unambiguous autapomorphies within Diplodocidae: frontals separated anteriorly by a U-shaped notch; squamosals restricted to the post-orbital region; presence of a postparietal foramen; a narrow, sharp and distinct sagittal nuchal crest; the paired basal tuber with a straight anterior edge in ventral view; anterior end of the prezygapophyses of mid- and posterior cervical vertebrae is often an anterior extension of the pre-epipophysis, which projects considerably anterior to the articular facet; anterodorsal corner of the lateral side of the posterior cervical vertebrae marked by a rugose tuberosity; posterior margin of the prezygapophyseal articular facet of posterior cervical vertebrae bordered posteriorly by conspicuous transverse sulcus; posterior cervical neural spines parallel to converging. The inclusion of K. siberi and several newly described characters into a previously published phylogenetic analysis recovers the new taxon as basal diplodocine, which concurs well with the low stratigraphical position of the holotype specimen. Dinheirosaurus and Supersaurus now represent the sister clade to Apatosaurus and Diplodocinae and therefore the most basal diplodocid genera. The geographical location in the less known northern parts of the Morrison Fm., where K. siberi was found, corroborates previous hypotheses on faunal provinces within the formation. The probable subadult ontogenetic stage of the holotype specimen allows analysis of ontogenetic changes and their influence on diplodocid phylogeny.

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Non-catalytic cellulosomal carbohydrate-binding modules (CBMs) are responsible for increasing the catalytic efficiency of cellulosic enzymes by selectively putting the substrate (a wide range of poly- and oligosaccharides) and enzyme into close contact. In the present work we carried out an atomistic rationalization of the molecular determinants of ligand specificity of a family 11 CBM from thermophilic C. thermocellum (CtCBM11), based on a NMR and molecular modeling approach. We have determined the NMR solution structure of CtCBM11 at 25 and 50 ºC and derived information on the residues of the protein involved in ligand recognition and on the influence of the length of the saccharide chain on binding. We obtained models of the CtCBM11/cellohexaose and CtCBM11/cellotetraose complexes by docking in accordance with the NMR experimental data. Specific ligand/protein CH-π and Van der Waals interactions were found to be determinant for the stability of the complexes and for defining specificity. Using the order parameters derived from backbone dynamics analysis in the presence and absence of ligand and at 25 and 50 ºC, we determined that the protein’s backbone conformational entropy is slightly positive. This data in combination with the negative binding entropy calculated from ITC studies supports a selection mechanism where a rigid protein selects a defined oligosaccharide conformation.

In this work we propose a stochastic model for the design and planning of closed-loop supply chains.
Uncertainties in demand and return volumes are modelled together with uncertain transportation
costs. A two-stage stochastic programming is developed and a sensitivity analysis to the worst-case
probability is performed in order to test the solution robustness. Finally, in order to prove the
goodness of the stochastic approach, the value of the stochastic solution and the value of perfect
information are computed. An example based on a real case shows the model applicability.

This work aimed to study the effect of different pre-treatments applied to a potato peel residue, in a thermophilic Anaerobic Digestion (AD) process. All samples were subjected to a mechanical pre-treatment through milling to a particle size below 2 mm. The thermal pre-treatments applied consisted of autoclaving the residue at a gauge pressure of 1.2 bar, under a temperature of 122°C, and for 20, 35 and 55 minutes: assays E122.20, E122.35 and E122.55, respectively. The control assay was performed on a ground residue, which was not submitted to any thermal pre-treatment. All pre-treated residues were subjected to an AD process in a CSTR reactor at 49±1°C. The experimental data showed that the highest methane percentages were very similar (about 92% v/v) for all samples submitted to the thermal pre-treatments. For the control assay, the highest percentage of methane was 87.9% (v/v). The highest biogas yields were recorded in the trial E122.35 (646±50 cm3.g-1 CODremoved), against only 250±20 cm3.g-1 CODremoved for the control assay. The highest biogas yields for VSremoved were attained in the assays E122.55 and E122.35, with values of 646±48 cm3.g-1 VSremoved and 634±59 cm3.g-1 VSremoved, respectively. Globally, the yields registered for the assay E122.35 were similar to those determined in the assay E122.55. Due to the lower energy consumption during the pre-treatment performed in the assay E122.35, this was considered to be the most suitable pre-treatment for this type of residue.