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This study looks at the analysis of the interface between Fiber Reinforced Polymer (FRP)-to-parent material bonded interfaces. The performance of FRP-to-parent material bonded joints for the Externally Bonded Reinforcement (EBR) technique is numerically modelled with the PFC2D software which is based on the Distinct Element Method (DEM). It is believed that this represents the first time the DEM has been used to simulate the delamination process of FRP-to-parent material bonded joints. In order to validate the analysis performed with the DEM, a Pull-out test with no slip constrains was modelled and different linear bond-slip laws were assumed. The numerical results revealed that the DEM is capable of estimating with good accuracy the exact solutions of bond stresses, strains or slippages along the bonded length for linear bond-slip laws. The bi-linear law available in PFC2D was then compared to the numerical results obtained from other another code developed by the author. The delamination process of Pull-out tests with slip constrain at one of the free ends of the FRP plate is also described and analyzed. The results obtained from the DEM revealed that the delamination process ends with stiffness equal to the axial stiffness of the FRP plate. This evidence highlights the need to design mechanical anchor devices capable of preventing premature debonding which is known to occur on EBR systems.

The human macrophage galactose-type lectin (hMGL) is a key physiological receptor for the carcinoma-associated Tn antigen (GalNAc-α-1-O-Ser/Thr) in mucins. We herein report NMR- and modeling-based data on the molecular recognition features of synthetic Tn-bearing glycopeptides by hMGL. Cognate epitopes on the sugar and matching key amino acids involved in the interaction have been identified by saturation transfer difference (STD) NMR spectroscopy. Only the amino acids close to the glycosylation site in the peptides are involved in lectin contact. Moreover, control experiments with non-glycosylated MUC1 peptides unequivocally showed that the sugar residue is essential for hMGL binding, as is Ca2+. The dissociation constants (Kd) have been estimated by STD titrations and/or STD competition experiments and show that Gal was a poor binder for hMGL, with a Kd in the mM range, while GalNAc and MUC1 Tn-glycopetides reached Kd values in the lower μM range. STD-based results suggested a distinct interacting epitope for the two monosaccharides. NMR data have been complemented with molecular dynamics simulations and Corcema- ST to establish a 3D view on the molecular recognition process between Gal, GalNAc and the Tn-presenting glycopeptides and hMGL. Gal and GalNAc have a dual binding mode with opposite trend of the main interaction pattern and the differences in affinity can be explained by additional hydrogen bonds and CH-π contacts involving exclusively the NHAc moiety.

— Human-Computer Interaction (HCI) faces a great challenges in what concerns the creation of a fully natural interface that is able to recognize a wide range of hand gestures in real-time. Lately efforts have been made by the research community catalyzed by the wide appearance of depth sensors such as the one from the Microsoft Kinect sensor. Nevertheless the available solutions struggle to robustly recognize hand gestures since, compared with the rest of the body, the hand is a small region with many joints, difficult to recognize and ultimately track. This paper proposes a hand shape recognition method that takes advantage of the depth sensor and the joint tracking ability of Microsoft Kinect sensor. The proposed method relies on the analysis of the hand contour or outline and compares it with previously stored templates achieving a good recognition ratio and proving it eligible
for real-time scenarios.

The enhancement of the mechanical behaviour of reinforced concrete (RC) columns with regard to axial compression is an up-to-date concern, namely if the strengthening of existing structures is to be considered. In view of this, external confinement with FRP systems has been tested in order to become a feasible technique, since it seems to have important advantages over other systems such as its high strength and stiffness in relation to weight and its improvement of strength and ductility while confining RC columns. Square columns confined with FRP show a more complex interpretation of their behaviour, when compared to circular columns. Accordingly, the present work includes the analysis of two experimental programs regarding axial compression on CFRP confined RC columns: one on circular and square specimens with different corner radii; the other on square specimens with side lengths ranging from medium to large. Based on this, modelling equations are proposed to predict maximum axial load, axial strain and lateral strain, as well as the entire behaviour until failure with curves of axial load-axial strain and axial load-lateral strain. The modelling results show that the analytical curves are in general agreement with the presented experimental curves for a wide range of dimensions.

The International Energy Agency (IEA), through the Solar Heating and Cooling programme (SHC) Task 40 and the Energy Conservation in Buildings and Community Systems programme (ECBCS, now named EBC) Annex 52, works towards developing a common understanding and setting up the basis for an international definition framework for Net Zero Energy Buildings (Net ZEBs). One of the subtasks of this programme?SubTaskC focuses benchmarking the Net ZEBs around the world to identify the innovative solutions sets that makes up this new type of building. This paper presents an overview of the work conducted by the participants of Subtask C and of Zero Energy Building projects that have been identified.

The use of powerful mobile devices, like smartphones, tablets and laptops, are changing the way programmers develop software. While in the past the primary goal to optimize software was the run time optimization, nowadays there is a growing awareness of the need to reduce energy consumption. This paper presents a technique and a tool to detect anomalous energy consumption in Android applications, and to relate it directly with the source code of the application. We propose a dynamically calibrated model for energy consumption for the Android ecosystem, and that supports different devices. The model is then used as an API to monitor the application execution: first, we instrument the application source code so that we can relate energy consumption to the application source code; second, we use a statistical approach, based on fault-localization techniques, to localize abnormal energy consumption in the source code.

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The main focus of this paper is the teacher’s representational fluency in a context of graphing calculator use. The conclusions reached point to a more intensive use of some representations over the others, suggesting that technology turns numerical or tabular representation into two different representations.

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Abstract This work addresses the direct identification of cohesive law of Pinus pinaster in mode II. The end-notched flexure (ENF) test is selected for mode İI\} loading. The strain energy release rate in mode İI\} (GII) is determined according to the compliance-based beam method (CBBM) by processing the global load�displacement curve, without requirements to monitor the crack length during test. The fracture test is coupled with digital image correlation (DIC) for the local measurement of the crack tip opening displacement in mode İI\} (wII). Using a direct method, the cohesive law in mode İI\} (sII�wII) is determined by differentiating the GII�wII relationship. The procedure is validated from both numerical, using finite element analyses including cohesive zone modelling, and experimental approaches. The methodology and accuracy on this reconstruction is discussed. It is concluded that the proposed data reduction scheme is suitable for assessing the cohesive law of P. pinaster in mode II.