Os partidos políticos deveriam ter a capacidade e a vontade de intervir neste tipo de decisão, trazendo para o debate parlamentar os temas relacionados com tecnologias emergentes. Para isso, há que ter uma posição própria sobre os riscos e as vantagens que essas tecnologias podem trazer

The structural and chemical diversity of β-glucans is reflected on the variety of essential biological roles tackled by these polysaccharides. This natural heterogeneity requires an elaborate assortment of enzymatic mechanisms to assemble, degrade or modify, as well as to extract their full biotechnological potential. Recent metagenomic efforts have provided an unprecedented growth in potential new biocatalysts, most of which remain unconfirmed or uncharacterized. Here we report the first biochemical and structural characterization of two bacterial β-glucanases from the recently created glycoside hydrolase family 157 (LaGH157 and BcGH157) and investigate their molecular basis for substrate hydrolysis. Structural analysis by X-ray crystallography revealed that GH157 enzymes belong to clan GH-A, possessing a (β/α)8-barrel fold catalytic domain, two β-sandwich accessory domains and two conserved catalytic glutamates residues, with relative positions compatible with a retaining mechanism of hydrolysis. Specificity screening and enzyme kinetics suggest that the enzymes prefer mixed-linkage glucans over β-1,3-glucans. Activity screening showed that both enzymes exhibit pH optimum at 6.5 and temperature optimum for LaGH157 and BcGH157 at 25 °C and 48 °C, respectively. Product analysis with HPAEC-PAD and LC-MS revealed that both enzymes are endo-1,3(4)-β-glucanases, capable of cleaving β-1,3 and β-1,4-linked glucoses, when preceded by a β-1,3 linkage. Moreover, BcGH157 needs a minimum of 4 subsites occupied for hydrolysis to occur, while LaGH157 only requires 3 subsites. Additionally, LaGH157 possesses exohydrolytic activity on β-1,3 and branching β-1,6 linkages. This unusual bifunctional endo-1,3(4)/exo-1,3–1,6 activity constitutes an expansion on our understanding of β-glucan deconstruction, with the potential to inspire future applications.

Allosaurus is one of the most famous theropod dinosaurs, but the validity and relationships between the different species have been confusing and often questioned. Portugal is relevant to the understanding of the genus in light of the discovery of A. europaeus ML415 from the Early Tithonian of Lourinhã and Allosaurus MNHNUL/AND.001 from Andrés. However, the exact classification and validity of these two specimens has always been controversial. The presence of Allosaurus in Portugal is strong evidence for a North America–Europe Late Jurassic dispersal, later supported by other taxa. A detailed cranial description and specimen-based phylogeny were performed and resolved many of the open questions: (1) The diversity of Allosaurus is limited to three named species: A. fragilis, A. europaeus, and A. jimmadseni. (2) Nine autapomorphies were found in A. europaeus, confirming the validity of the species. (3) Phylogenetic analyses place both Portuguese specimens in the genus Allosaurus, based on the following synapomorphies: jugal bone lateral view, relative heights of quadratojugal prongs, the dorsal prong is equal in height, the jugal bone in lateral view shows shallow accessory pneumatization of the antorbital fossa, the palatine pneumatic recess shape is small, and lacrimal horn morphology has a triangular horn. (4) The Andrés specimen is placed with the A. europaeus and they are considered here to be the same species, which is paleo-geographically and biochronologically congruent. (5) A. europaeus and A. jimmadseni are sister taxa and closer to each other than to A. fragilis. The genus is distributed in occurrences from the United States, Germany, and Portugal, and from the Late Kimmeridgian to the Late Tithonian, while the Cenomanian report from Japan is reidentified as Segnosaurus.

As mentioned in the introduction to this volume, artificial intelligence (AI) functionalities are swiftly becoming integral to knowledge work and digital services. They are, however, also applied in all areas of human work. That is making the public services in Portugal more accessible and efficient. Since mid-90s, with the national strategy towards the Information Society (Missão para a Sociedade da Informação), a wide program for the promotion and development of public digital services have started. In the last decades, and with the definition of this national strategy, successive governments and the national parliament have contributed to stimulate democratic participation, and support decision-making and policy development.

This chapter deals with the role of technology in industrial production. Hereby, the enabling character of technology will be strengthened from the perspective of Technology Assessment (TA) in various countries and epochs. Besides the remarkable evolution of technological progress in this sector, the interrelationship of technology with human labor, the creation of specific institutional settings as well as the innovation circles by capital investments must be considered when assessing industrial production. The argumentation line of the article is based on the hypothesis, that the increase of TA studies in the last three decades on industrial production indicates the societal problem orientation of these technological innovations and its impact on employment and job qualification. TA expertise raised awareness of the positive and negative impact of technologies in industry which brings together a variety of options for the decision makers. Furthermore, discourses on ethical values on the future of (industrial) work are highlighted by TA.

The introduction of exoskeletons by many companies has often resulted in potential users not wanting to wear them. Evaluations of the exoskeleton reveal benefits of use, including ergonomic advantages and a reduction of work-related musculoskeletal disorders. How can this contradiction be explained? By searching the available literature, we can identify the methods used to develop these devices and the methods employed to evaluate their acceptance and benefit. By looking at the product from different viewpoints and involving different disciplines, we will get to the root of this discrepancy. Our findings indicate that the product definition, development focus, and evaluation methods do not sufficiently and adequately address the primary goal of exoskeletons. The development of such devices should be prioritized not only for the delivery of support but also for the motivation of the user. Finally, we put forward the proposal to discuss the establishment of a novel development method for the prospective elaboration of exoskeletons.

ABSTRACTVirtual palaeontology is a growing field, leading palaeontologists to better understand the microanatomy of many extinct species. The application of techniques such as CT and μCT-scanning allows the researchers to study micro-anatomical features in a non-invasive way and make inferences on the palaeobiology of animals. Dinosaurs have been extensively studied using these techniques, with particular focus on the microanatomy of the cranium, whereas relatively little is known of other cranial elements, such as the lower jaw. Here, we aim to fill this gap, describing the microanatomy of the specimen ML 768, an isolated dentary belonging to a dryosaurid iguanodontian dinosaur from the Upper Jurassic of Lourinhã Fm. The dentary ML 768 was subjected to μCT-scanning, and subsequently the data were segmented in Avizo and rendered in Blender. We identified functional and replacement teeth, recognising remnants of old replacement cycles. Furthermore, we mapped a rich neurovascular network present in the dentary and compared it with reference literature. We found that the high vascularisation is shared with other cerapodan dinosaurs with high tooth replacement rates, although homoeostasis may have also played a role in the development of this condition. Further evidence is needed to appreciate the macroevolutionary significance of these findings.

Political and economic crises and issues such as global warming, decreased fossil fuel reserves, environmental pollutions and acid rains are just some of the problems caused by improper energy consumption. Energy efficiency optimization with the right policy and definition of accurate scientific methods proven in energy consumption includes planning, enforcement, organizing permanent control, and continuously reviewing technology upgrades. Additionally, developing legal solutions to implement these programs prevents the destruction and waste of energy resources and reduces the side effects of improper energy consumption. The shape of the city and its components can affect the city’s quality and its spaces, as well as the air quality change, creating a particular climate in their area, causing phenomena such as heat islands, dust, rain, albedo, atmospheric inversion, and some others. By making changes in the shape of the city, both on a large scale and a micro-scale, atmospheric currents and, consequently, air quality in cities can be improved. Urban morphological indicators, including building height, building type, occupancy level, segmentation, block size, block shape, density, and urban green, can affect the weather and climate conditions outside and inside the building and, thus, the energy demand in the areas. By creating effective reforms in the model of configuration of the urban regions, including the pattern of land fragmentation, the physical characteristics of buildings, the network of passages and open spaces, it is possible to increase the energy efficiency of buildings in the long term in the regional(synoptic) climatic conditions of the city and the neighbourhood.

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Stegosaurs are a small but iconic clade of ornithischian dinosaurs. They and their sister taxa, the ankylosaurs, formed the clade Eurypoda which means ‘broad-footed’. Here, we describe a stegosaur from the Upper Jurassic Qigu Formation of Xinjiang, China, based on an associated partial skeleton that includes axial, pectoral girdle, pelvic girdle, limb and armor elements. It can be diagnosed as a new taxon, Angustungui, based on numerous autapomorphies. Some morphologies of Angustungui are more similar to the taxa from Europe, Africa and North America than to those from Asia. Our phylogenetic analysis recovers it as the sister taxon of Loricatosaurus. More importantly, the narrow and claw-shaped ungual of Angustungui proves that Eurypoda, at least stegosaur, has claw-shaped unguals. Besides, we revised the character scores for Chinese stegosaurs based on observations of the specimens.Competing Interest StatementThe authors have declared no competing interest.

Since Seymour Papert's work with the Logo programming language in the 1960s, there has been a prevailing belief in the effectiveness of visual programming environments for teaching programming to children and novices. As these platforms evolved and became more prevalent, using block programming to teach children and beginners became increasingly more common. However, modern block programming platforms like Scratch and Code.org excessively restrict educators by not allowing them to create custom exercises in the platform. They also tend to make programming a solo activity, not allowing for collaboration and cooperation between learners (Scratch is an exception in this regard). Additionally, they are usually located in standalone websites instead of being implemented in locations that students already frequent regularly. Having identified these gaps in the field of block programming environments, this paper proposes NextBlocks, a new block programming platform implemented as a Moodle plugin. This platform enables educators to create custom exercises, emphasizing social perception and collaboration features. It supports features that are uncommon in block programming environments, contributing to a more interactive and engaging learning experience. Furthermore, being integrated into the Moodle Learning Management System makes NextBlocks more easily accessible within the educational framework. As an open-source platform, besides solving current challenges, it can also serve as a foundation for future expansion by the education community. This paper explores some of the unique features of NextBlocks, presents a case study on the platform, and discusses its potential contributions to enhancing programming education for beginners within a collaborative learning environment.

Allosaurus Marsh, 1877 is one of the most iconic theropods of the Late Jurassic of USA and Portugal. However,
since the first description the genus was used as taxonomical wastebasket to which several species were
described. We revisit three type specimens, Allosaurus fragilis YPM 1930, A. atrox YPM 1890 and A. ferox USNM
2315. We interpret the vertebral material of A. atrox and support it as a junior synonym of A. fragilis, and A. ferox
as Allosaurus indet. rather than A. fragilis.

This study was conducted while 9th grade students learn to solve inequalities and seeks to understand their approach to solving problems with a real-life context. Specifically, the aim is to understand: (1) What are the main characteristics of the students’ approaches to the proposed problems? (2) What is the impact of the real context on the students’ resolutions? A qualitative and interpretative methodology is adopted, based on case studies, with data collected through documentary collection and audio recording of discussions between a pair of students while solving problems. The main conclusions suggest a trend to approach problems without establishing immediate connections with what was being done in the classroom, with students’ decisions being essentially guided by criteria of simplicity. The real context of the problems seems to have the potential to develop in students a more integrated mathematics, focused on understanding and not so much on the repetition of mechanical and meaning-independent procedures. The students’ familiarization with the context in question is one of the aspects highlighted by this study.

In Portugal, digital transition was structured with national public policies since 2003. In 2017, initiatives for the adoption of Industry 4.0 concepts are implemented in Portugal. We analysed the diffusion and implementation of these technologies, in Portugal. Some questions were raised: has the interplay between public policies, state agencies and industrial relations players in the process been articulated, as in Germany? What have been the effects of these technologies on workers and organisations? Are the public initiatives in place enough or more is needed? Qualitative and quantitative approaches were used to collect evidence on the main features and constraints of a public policy for Industry 4.0, based on the case study of the automotive sector in Portugal. Findings suggest the need to balance regulatory policies on data related risks, and investment policies towards education, training and organisational innovation are needed to complement technology development and adoption support.