Publications

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2020
Marques, Sofia Santos; Artur Silva; Manuel A. M. S. M. B. "Sustainable Amidation Reactions – Recent Advances." Eur J. Org. Chem. (2020). Abstract

Herein, we present a selection of sustainable amidation processes, that have contributed to solving the problems associated with traditional methods. Novel reagents and methods are described, including boron‐based reagents, the use of metallic and organometallic catalysts as well as metal‐free methods using milder and versatile oxidants.

2019
Marques, Diogo Poeira João Macara Hélio Faustino Jaime Coelho Pedro Gois Manuel L. A. S. M. P. "Hypervalent Iodine Mediated Sulfonamide Synthesis." Eur. J. Org. Chem. (2019): 2695-2701.
F. Queda, G.Covas, Silva A.Santos R.Bronze Javier Cañada Filipe Manuel Marques T. C. M. F. "A top-down chemo-enzymatic approach towards N-acetylglucosamine-N-acetylmuramic oligosaccharides: Chitosan as a reliable template." Carbohydr. Polym.. 224 (2019): 115133.
2018
Marques., Luísa Carvalho; Fausto Queda; Cátia Almeida; Sérgio Filipe; Manuel C. R. V. R. M. ""From a Natural Polymer to Relevant NAG-NAM Precursors"." Asian J. Org. Chem.. 7 (2018): 2544-2551.
A. Sofia Santos, Ana C. Mortinho, Manuel Marques M. B. "Metal-Catalyzed Cross-Coupling Reactions on Azaindole Synthesis and Functionalization." Molecules. 23.10 (2018): 2673-2683.
2017
Purificação S. I., Pires M. J. D., Rafael Santos Sofia Marques R. A. M. M. "1. One-Pot Synthesis of 1,2-Disubstituted 4 ‑ , 5 ‑ , 6 ‑ , and 7 ‑ Azaindoles from Amino ‑o‑ halopyridines via N ‑ Arylation/Sonogashira/Cyclization Reaction." Org. Lett.. 19 (2017): 5118-5121.
Pires M. J. D., Purificação S. I., Santos Sofia Marques A. M. M. B. *. "2. The Role of PEG on Pd- and Cu-Catalyzed Cross-Coupling Reactions." Synthesis. 49 (2017): 2337-2350.
Soares A., Estevão M. S., Marques Kovalishyn Latino Aires-de-Sousa Ramos Viveiros Ma M. M. B. * V. "3. Synthesis and Biological Evaluation of Hybrid 1,5-and 2,5-Disubstituted Indoles as Potentially New Antitubercular Agents." Med. Chem. . 13 (2017): 439-447.
2016
Carvalho L. C. R., Queda F., Santos Marques C. V. A. M. M. "5. Selective Modification of Chitin and Chitosan: on the route to tailored oligosaccharides." Chem. Asian J.. 11 (2016): 3468-3481.
Pires M. J. D., Poeira D. L., Purificação Marques S. I. M. M. B. "Synthesis of Substituted 4 ‑ , 5 ‑ , 6 ‑ , and 7 ‑ Azaindoles from Aminopyridines via a Cascade C − N Cross-Coupling/Heck Reaction." Org. Lett.. 18.- (2016): 3250−3253.
2015
Pires M. J. D., Poeira D. L., Marques M. M. B. "1. Metal-Catalyzed Cross-Coupling Reactions of Aminopyridines." Eur. J. Org. Chem. . 33.- (2015): 7197-7234 .
Padmanaban M, Carvalho L. C. R., Petkova Lee Santos Marques Maulide D. J. W. A. "2. Investigation of Cationic Claisen-type Electrophilic Rearrangements of Amides ." Tetrahedron. 71.- (2015): 5994-6005.
Carvalho L. C. R., Ribeiro D., Seixas Silva Silva Nave Martins Erhardt Fernandes Cabri R. S. G. R. A. "3. Synthesis and Evaluation of new Benzimidazole-Based COX Inhibitors: a Naproxen-like Interaction Detected by STD-NMR." RSC Advances. 5.- (2015): 49098-149109.
2014
Enugala R., Pires M. J.D., Marques Manuel M. B. *. "4. Synthesis of the NAG–NAM disaccharide via a versatile intermediate." Carbohydrat Res. . 384.- (2014): 112-118.
Ribeiro D., Freitas M., Tomé Silva Artur Porto Cabrita Marques Fernandes S. M. M. S. "5. Inhibition of LOX by Flavonoids: a Structure Activity Relationship Study." Eur. J. Med. Chem. . 72.- (2014): 137-145.
2013
Carvalho L. C., Pires M. J. D., Marques M. M. B. "6. Pd-catalysed Amination on a Soluble Polymer Support: Arylation of Anilines with PEG-supported Aryl Halides." RSC Advances . 3.- (2013): 25711-25715.
2012
Estêvão M. E., Carvalho L. C., Freitas Gomes Viegas Manso Fernandes Cabrita Erhardt Marques Ma M. A. A. J. "Indole based cyclooxygenase inhibitors: synthesis, biological evaluation, docking and NMR screening." Eur. J. Med. Chem.. 54.- (2012): 823-833.
Enugala R., Carvalho L. C., Pires Marques Manuel M. J. D. M. B. "Stereoselective glycosylation of glucosamine: the role of the N-protecting group." Chem. Asian J. . 7.- (2012): 2482-250.
Enugala R., Marques M. M. B. *. "Synthesis of a 3-hydroxyl- free N-acetyl glucosamine disaccharide." Arkivoc. vi (2012): 90-100.
Estêvão M. E., Duarte F. J., Fernandes Santos Marques Manuel E. A. G. M. "Unexpected reactivity of trifluoromethylated olefins with indole: a mechanistic investigation." Tetrahedron Lett.. 53 (2012): 3132-2136.
2011
Estêvão M. S., Carvalho L. C. R., Ferreira Fernandes Marques L. E. M. M. "Analysis of the antioxidant activity of an indole library: cyclic voltammetry versus ROS scavenging activity." Tetrahedron Lett.. 52 (2011): 101-106.
Viegas A., Manso J., Marques Manuel Cabrita M. B. E. J. *. "Binding of Ibuprofen, Ketorolac, and Diclofenac to COX-1 and COX-2 Studied by Saturation Transfer Difference NMR." J. Med. Chem.. 54 (2011): 8555-8562.
Carvalho L. C., Fernandes E., Marques Manuel M. B. *. "Developments Towards Regioselective Synthesis of 1,2-Disubstituted Benzimidazoles." Chem. Eur. J.. 17 (2011): 12544-12555.
2010
Estêvão M. E., Carvalho L. C., Ribeiro Couto Freitas Gomes Ferreira Fernandes Marques Manuel D. D. M. A. "Antioxidant activity of unexplored indole derivatives: Synthesis and screening." Eur. J. Med. Chem.. 45 (2010): 4869-4878.
Carvalho L. R., Corvo M. C., Enugala Cabrita Marques R. E. J. M. "Application of HR-MAS NMR in the solid-phase synthesis of a glycopeptide using Sieber amide resin." Magn. Reson. Chem.. 48 (2010): 323-330.