Publications

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2010
FRANCO, P. Q., Silva, M. A. G., J. C. e BORGES, and J.P. Produção de fibras de hidroxiapatite por electrofiação. Vol. 22., 2010. Abstract
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2012
JDS, Martins, Henriques CMR, Borges JPMR, Prata SGM, Almeida M, and Silva JAMC Biodegradable occlusive membranes for oral and periodontal surgery. Vol. 6. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 6., 2012. Abstract
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PI, Soares, Dias SJ, Novo CM, Ferreira IM, Ferreira IM, and Borges JP. "Doxorubicin vs. Ladirubicin: Methods For Improving Osteosarcoma Treatment." Mini reviews in medicinal chemistry. 12 (2012): 1239-1249. Abstract
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AFR, Pimenta, Baptista AC, Carvalho T, Brogueira P, Lourenco NMT, Afonso CAM, Barreiros S, Vidinha P, and Borges JP. "Electrospinning of Ion Jelly fibers." MATERIALS LETTERS. 83 (2012): 161-164. Abstract
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SR, Gomes, Rodrigues GM, Martins GG, Henriques CM, Borges JP, and Silva JC How fibroblasts respond to different biomaterials: comparative adhesion and proliferation studies. Vol. 6. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 6., 2012. Abstract
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GSL, Gaspar, Silva SJC, and Borges BJP Production and characterization of chitosan/calcium phosphate composite microspheres for bone tissue engineering therapeutics. Vol. 6. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 6., 2012. Abstract
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2013
Ana, Baptista, Ferreira Isabel, and Borges João Paulo. "Cellulose-based composite Systems for Biomedical Applications." Biomass-based Biocomposites. Eds. Vijay Kumar Thakur, and Amar Singh Singha. Smithers Rapra, 2013. 47-60. Abstract
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dos Santos, Renato, Ângelo Rocha, Ana Matias, Catarina Duarte, Isabel Sá-Nogueira, Nuno Lourenço, João Paulo Borges, and Pedro Vidinha. "Development of antimicrobial Ion Jelly fibers." RSC Advances. 3 (2013): 24400-24405. Abstract

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Ferreira, I.; Baptista, AC; Leitao, JP; Soares, J.; Fortunato, E.; Martins, R.; Borges, and JP. "Strongly Photosensitive and Fluorescent F8T2 Electrospun Fibers." Macromolecular Materials and Engineering. 298 (2013): 174-180. Abstract

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2014
Soares, PI, AM Alves, LC Pereira, JT Coutinho, IM Ferreira, CM Novo, and J. P. Borges. "Effects of surfactants on the magnetic properties of iron oxide colloids." J Colloid Interface Sci.. 419 (2014): 46-51. AbstractWebsite

Iron oxide nanoparticles are having been extensively investigated for several biomedical applications such as hyperthermia and magnetic resonance imaging. However, one of the biggest problems of these nanoparticles is their aggregation.

Taking this into account, in this study the influence of three different surfactants (oleic acid, sodium citrate and Triton X-100) each one with various concentrations in the colloidal solutions stability was analyzed by using a rapid and facile method, the variation in the optical absorbance along time.

The synthesized nanoparticles through chemical precipitation showed an average size of 9 nm and a narrow size distribution. X-ray diffraction pattern and Fourier Transform Infrared analysis confirmed the presence of pure magnetite. SQUID measurements showed superparamagnetic properties with a blocking temperature around 155 K. In addition it was observed that neither sodium citrate nor Triton X-100 influences the magnetic properties of the nanoparticles. On the other hand, oleic acid in a concentration of 64 mM decreases the saturation magnetization from 67 to 45 emu/g. Oleic acid exhibits a good performance as stabilizer of the iron oxide nanoparticles in an aqueous solution for 24 h, for concentrations that lead to the formation of the double layer.

JP, Borges, Canejo JP, Fernandes SN, Brogueira P, and GODINHO MH. "Cellulose‐Based Liquid Crystalline Composite Systems." Nanocellulose Polymer Nanocomposites: Fundamentals and Applications. Ed. Vijay Kumar Thakur. Scrivener Publishing - Wiley. Scrivener Publishing - Wiley, 2014. 215-235. Abstract
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2015
João, Carlos Filipe Cidre, Jorge Carvalho Silva, and João Paulo Borges. "Chitin-Based Nanocomposites: Biomedical Applications." Eco-friendly Polymer Nanocomposites. Springer India, 2015. 439-457. Abstract
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Echeverria, Coro, Paula Soares, Ana Robalo, Laura Pereira, Carlos M. M. Novo, Isabel Ferreira, and João Paulo Borges. "One-pot synthesis of dual-stimuli responsive hybrid PNIPAAm-chitosan microgels." Materials & Design. 86 (2015): 745-751. Abstract
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Soares, Paula I. P., Frederik Lochte, Coro Echeverria, Laura CJ Pereira, Joana T. Coutinho, Isabel M. M. Ferreira, Carlos M. M. Novo, and others. "Thermal and magnetic properties of iron oxide colloids: influence of surfactants." Nanotechnology. 26 (2015): 425704. Abstract
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2016
Soares, Paula I. P., Ana Isabel Sousa, Jorge Carvalho Silva, Isabel M. M. Ferreira, Carlos M. M. Novo, and João Paulo Borges. "Chitosan-based nanoparticles as drug delivery systems for doxorubicin: Optimization and modelling." Carbohydrate polymers. 147 (2016): 304-312. Abstract
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Marques, Susana CS, Paula I. P. Soares, Coro Echeverria, Maria H. Godinho, and João P. Borges. "Confinement of thermoresponsive microgels into fibres via colloidal electrospinning: experimental and statistical analysis." RSC Advances. 6.80 (2016): 76370-76380. Abstract
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Soares, Paula I. P., César AT Laia, Alexandra Carvalho, Laura CJ Pereira, Joana T. Coutinho, Isabel M. M. Ferreira, Carlos M. M. Novo, and João Paulo Borges. "Iron oxide nanoparticles stabilized with a bilayer of oleic acid for magnetic hyperthermia and MRI applications." Applied Surface Science. 383 (2016): 240-247. Abstract
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João, Carlos FC, Ana C. Baptista, Isabel M. M. Ferreira, Jorge C. Silva, and João P. Borges. "Natural Nanofibres for Composite Applications." Fibrous and Textile Materials for Composite Applications. Springer Singapore, 2016. 261-299. Abstract
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João, Carlos, Rute Almeida, Jorge Silva, and João Borges. "A simple sol-gel route to the construction of hydroxyapatite inverted colloidal crystals for bone tissue engineering." Materials Letters. 185 (2016): 407-410. Abstract
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Soares, Paula I. P., Diana Machado, César Laia, Laura CJ Pereira, Joana T. Coutinho, Isabel M. M. Ferreira, Carlos M. M. Novo, and João Paulo Borges. "Thermal and magnetic properties of chitosan-iron oxide nanoparticles." Carbohydrate polymers. 149 (2016): 382-390. Abstract
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Soares, Paula I. P., Ana Isabel Sousa, Isabel M. M. Ferreira, Carlos M. M. Novo, and João Paulo Borges. "Towards the development of multifunctional chitosan-based iron oxide nanoparticles: Optimization and modelling of doxorubicin release." Carbohydrate Polymers. 153 (2016): 212-221. Abstract
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2017
João, Carlos FC, Coro Echeverria, Alexandre Velhinho, Jorge C. Silva, Maria H. Godinho, and João P. Borges. "Bio-inspired production of chitosan/chitin films from liquid crystalline suspensions." Carbohydrate Polymers. 155 (2017): 372-381. Abstract
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João, Carlos FC, Ana T. Kullberg, Jorge C. Silva, and João P. Borges. "Chitosan Inverted Colloidal Crystal scaffolds: Influence of molecular weight on structural stability." Materials Letters. 193 (2017): 50-53. Abstract
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Soares, P. I. P., C. Echeverria, AC Baptista, C. F. C. João, S. N. Fernandes, A. P. C. Almeida, JC Silva, M. H. Godinho, and J. P. Borges Hybrid polysaccharide-based systems for biomedical applications. Hybrid Polymer Composite Materials: Applications., 2017. AbstractWebsite

Hybrid materials have been widely studied for structural applications. Polysaccharide-based fibers, especially cellulosic fibers, have been explored in the last two decades as substitutes of the traditional reinforcements made of glass or carbon fibers due to their mechanical properties. However, their biocompatibility, biodegradability, and chemistry have attracted the researchers and new developments in the field of smart and functional materials arise in diverse applications. This chapter will focus on the biomedical applications of polysaccharide-based smart and functional materials, namely those concerning biosensors and actuators, theranostic systems, and tissue-engineering applications. Special attention will be given to cellulose- and chitin/chitosan-based hybrid materials because these are the two most abundant polysaccharides and probably the most promising for the development of hybrid materials for biomedical applications. Biomimetic strategies for the development of smart and functional hybrid materials will also be highlighted. © 2017 Elsevier Ltd All rights reserved.

Mano, Francisca, Marta Martins, Isabel Sá-Nogueira, Susana Barreiros, João Paulo Borges, Rui L. Reis, Ana Rita C. Duarte, and Alexandre Paiva. "Production of Electrospun Fast-Dissolving Drug Delivery Systems with Therapeutic Eutectic Systems Encapsulated in Gelatin." AAPS PharmSciTech (2017): 1-7. Abstract
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