Publications

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2017
Watson, C., D. Niks, R. Hille, M. Vieira, B. Schoepp-Cothenet, AT Marques, MJ Romão, T. Santos-Silva, and J. M. Santini. "Electron transfer through arsenite oxidase: Insights into Rieske interaction with cytochrome c." Biochimica et Biophysica Acta - Bioenergetics. 1858 (2017): 865-872. Abstract
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Otrelo-Cardoso, A. R., R. R. Nair, MAS Correia, R. S. C. Cordeiro, A. Panjkovich, D. I. Svergun, T. Santos-Silva, and M. G. Rivas. "Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20." Scientific Reports. 7 (2017). Abstract
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Romão, MJ, C. Coelho, T. Santos-Silva, A. Foti, M. Terao, E. Garattini, and S. Leimkühler. "Structural basis for the role of mammalian aldehyde oxidases in the metabolism of drugs and xenobiotics." Current Opinion in Chemical Biology. 37 (2017): 39-47. Abstract
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2016
Correia, MAS, A. R. Otrelo-Cardoso, V. Schwuchow, K. G. V. Sigfridsson Clauss, M. Haumann, MJ Romão, S. Leimkühler, and T. Santos-Silva. "The Escherichia coli Periplasmic Aldehyde Oxidoreductase Is an Exceptional Member of the Xanthine Oxidase Family of Molybdoenzymes." ACS Chemical Biology. 11 (2016): 2923-2935. Abstract
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Martins, Marta, Pedro V. Baptista, Ana Soraia Mendo, Claudia Correia, Paula Videira, Antonio S. Rodrigues, J. Muthukumaran, Teresa Santos-Silva, Ana Silva, Fatima M. C. Guedes da Silva, Joana Gigante, Antonio Duarte, Malgorzata Gajewska, and Alexandra R. Fernandes. "In vitro and in vivo biological characterization of the anti-proliferative potential of a cyclic trinuclear organotin(IV) complex." Molecular Biosystems. 12 (2016): 1015-1023. Abstract
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Foti, Alessandro, Tobias Hartmann, Catarina Coelho, Teresa Santos-Silva, Maria Joao Romao, and Silke Leimkuehler. "Optimization of the Expression of Human Aldehyde Oxidase for Investigations of Single-Nucleotide Polymorphisms." Drug Metabolism and Disposition. 44 (2016): 1277-1285. Abstract
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2015
Correia, H. D., J. Marangon, CD Brondino, JJG Moura, MJ Romão, P. J. González, and T. Santos-Silva. "Aromatic aldehydes at the active site of aldehyde oxidoreductase from Desulfovibrio gigas: Reactivity and molecular details of the enzyme-substrate and enzyme-product interaction." Journal of Biological Inorganic Chemistry. 20 (2015): 219-229. Abstract
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Correia, Hugo D., Jacopo Marangon, Carlos D. Brondino, Jose J. G. Moura, Maria J. Romao, Pablo J. Gonzalez, and Teresa Santos-Silva. "Aromatic aldehydes at the active site of aldehyde oxidoreductase from Desulfovibrio gigas: reactivity and molecular details of the enzyme-substrate and enzyme-product interaction (vol 20, pg 219, 2015)." Journal of Biological Inorganic Chemistry. 20 (2015): 231. Abstract
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Seixas, Joao D., Marino F. A. Santos, Abhik Mukhopadhyay, Ana C. Coelho, Patricia M. Reis, Luis F. Veiros, Ana R. Marques, Nuno Penacho, Ana M. L. Goncalves, Maria J. Romao, Goncalo J. L. Bernardes, Teresa Santos-Silva, and Carlos C. Romao. "A contribution to the rational design of Ru(CO)(3)Cl2L complexes for in vivo delivery of CO." Dalton Transactions. 44 (2015): 5058-5075. Abstract
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Freire, D. M., M. G. Rivas, A. M. Dias, A. T. Lopes, C. Costa, T. Santos-Silva, S. Van Doorslaer, and P. J. González. "The homopentameric chlorite dismutase from Magnetospirillum sp." Journal of Inorganic Biochemistry. 151 (2015): 1-9. Abstract
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De Schutter, Amy, Hugo D. Correia, Diana M. Freire, Maria G. Rivas, Alberto Rizzi, Teresa Santos-Silva, Pablo J. Gonzalez, and Sabine Van Doorslaer. "Ligand Binding to Chlorite Dismutase from Magnetospirillum sp." Journal of Physical Chemistry B. 119 (2015): 13859-13869. Abstract
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Coelho, Catarina, Alessandro Foti, Tobias Hartmann, Teresa Santos-Silva, Silke Leimkuehler, and Maria Joao Romao. "Structural insights into xenobiotic and inhibitor binding to human aldehyde oxidase." Nature Chemical Biology. 11 (2015): 779-+. Abstract
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Coelho, C., A. Foti, T. Hartmann, T. Santos-Silva, S. Leimkühler, and MJ Romão. "Structural insights into xenobiotic and inhibitor binding to human aldehyde oxidase." Nature Chemical Biology. 11 (2015): 779-783. Abstract
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2014
Otrelo-Cardoso, Ana Rita, Viola Schwuchow, David Rodrigues, Eurico J. Cabrita, Silke Leimkuehler, Maria Joao Romao, and Teresa Santos-Silva. "Biochemical, Stabilization and Crystallization Studies on a Molecular Chaperone (PaoD) Involved in the Maturation of Molybdoenzymes." Plos One. 9 (2014). Abstract
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Pessoa, Joao Costa, Gisela Goncalves, Somnath Roy, Isabel Correia, Sameena Mehtab, Marino F. A. Santos, and Teresa Santos-Silva. "New insights on vanadium binding to human serum transferrin." Inorganica Chimica Acta. 420 (2014): 60-68. Abstract
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Otrelo-Cardoso, Ana Rita, Marcia Alexandra da Silva Correia, Viola Schwuchow, Dmitri I. Svergun, Maria Joao Romao, Silke Leimkuehler, and Teresa Santos-Silva. "Structural Data on the Periplasmic Aldehyde Oxidoreductase PaoABC from Escherichia coli: SAXS and Preliminary X-ray Crystallography Analysis." International Journal of Molecular Sciences. 15 (2014): 2223-2236. Abstract
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Otrelo-Cardoso, Ana Rita, Rashmi R. Nair, Marcia A. S. Correia, Maria G. Rivas, and Teresa Santos-Silva. "TupA: A Tungstate Binding Protein in the Periplasm of Desulfovibrio alaskensis G20." International Journal of Molecular Sciences. 15 (2014): 11783-11798. Abstract
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2013
Seixas, J. D., A. Mukhopadhyay, T. Santos-Silva, L. E. Otterbein, D. J. Gallo, S. S. Rodrigues, B. H. Guerreiro, A. M. L. Gon?alves, N. Penacho, A. R. Marques, A. C. Coelho, P. M. Reis, MJ Romão, and C. C. Romão. "Characterization of a versatile organometallic pro-drug (CORM) for experimental CO based therapeutics." Dalton Transactions. 42 (2013): 5985-5998. Abstract
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Mehtab, S., G. Gon?alves, S. Roy, A. I. Tomaz, T. Santos-Silva, M. F. A. Santos, MJ Romão, T. Jakusch, T. Kiss, and JC Pessoa. "Interaction of vanadium(IV) with human serum apo-transferrin." Journal of Inorganic Biochemistry. 121 (2013): 187-195. Abstract
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2012
Santos, M. F. A., J. D. Seixas, A. C. Coelho, A. Mukhopadhyay, P. M. Reis, MJ Romão, C. C. Romão, and T. Santos-Silva. "New insights into the chemistry of fac-[Ru(CO)3]2 + fragments in biologically relevant conditions: The CO releasing activity of [Ru(CO)3Cl2(1,3-thiazole)], and the X-ray crystal structure of its adduct with lysozyme." Journal of Inorganic Biochemistry. 117 (2012): 285-291. Abstract
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2011
Santos-Silva, T., A. Mukhopadhyay, J. D. Seixas, G. J. L. Bernardes, C. C. Romão, and MJ Romão. "CORM-3 reactivity toward proteins: The crystal structure of a Ru(II) dicarbonyl-lysozyme complex." Journal of the American Chemical Society. 133 (2011): 1192-1195. Abstract
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Santos-Silva, T., A. Mukhopadhyay, J. D. Seixas, G. J. L. Bernardes, C. C. Romão, and MJ Romão. "Towards improved therapeutic CORMs: Understanding the reactivity of CORM-3 with proteins." Current Medicinal Chemistry. 18 (2011): 3361-3366. Abstract
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2010
Ribeiro, T., T. Santos-Silva, V. D. Alves, FMV Dias, A. S. Luís, JAM Prates, LMA Ferreira, MJ Romão, and CMGA Fontes. "Family 42 carbohydrate-binding modules display multiple arabinoxylan-binding interfaces presenting different ligand affinities." Biochimica et Biophysica Acta - Proteins and Proteomics. 1804 (2010): 2054-2062. Abstract
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2009
Santos-Silva, T., F. Ferroni, A. Thapper, J. Marangon, P. J. González, A. C. Rizzi, I. Moura, JJG Moura, MJ Romão, and CD Brondino. "Kinetic, structural, and EPR studies reveal that aldehyde oxidoreductase from Desulfovibrio gigas does not need a sulfido ligand for catalysis and give evidence for a direct Mo-C interaction in a biological system." Journal of the American Chemical Society. 131 (2009): 7990-7998. Abstract
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Honzí?ek, J., A. Mukhopadhyay, T. Santos-Silva, MJ Romão, and C. C. Romão. "Ring-functionalized molybdenocene complexes." Organometallics. 28 (2009): 2871-2879. Abstract
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