Teresa Santos-Silva
Lab Structure-Based Drug Design
tsss *** at *** fct.unl.pt
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Coelho, Catarina, Alessandro Foti, Tobias Hartmann, Teresa Santos-Silva, Silke Leimkuehler, and Maria Joao Romao.
"
Structural insights into xenobiotic and inhibitor binding to human aldehyde oxidase
."
Nature Chemical Biology
. 11 (2015): 779-+.
Abstract
n/a
Coelho, C., A. Foti, T. Hartmann, T. Santos-Silva, S. Leimkühler, and MJ Romão.
"
Structural insights into xenobiotic and inhibitor binding to human aldehyde oxidase
."
Nature Chemical Biology
. 11 (2015): 779-783.
Abstract
n/a
Correia, H. D., J. Marangon, CD Brondino, JJG Moura, MJ Romão, P. J. González, and T. Santos-Silva.
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Aromatic aldehydes at the active site of aldehyde oxidoreductase from Desulfovibrio gigas: Reactivity and molecular details of the enzyme-substrate and enzyme-product interaction
."
Journal of Biological Inorganic Chemistry
. 20 (2015): 219-229.
Abstract
n/a
Correia, Hugo D., Jacopo Marangon, Carlos D. Brondino, Jose J. G. Moura, Maria J. Romao, Pablo J. Gonzalez, and Teresa Santos-Silva.
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Aromatic aldehydes at the active site of aldehyde oxidoreductase from Desulfovibrio gigas: reactivity and molecular details of the enzyme-substrate and enzyme-product interaction (vol 20, pg 219, 2015)
."
Journal of Biological Inorganic Chemistry
. 20 (2015): 231.
Abstract
n/a
Correia, MAS, A. R. Otrelo-Cardoso, V. Schwuchow, K. G. V. Sigfridsson Clauss, M. Haumann, MJ Romão, S. Leimkühler, and T. Santos-Silva.
"
The Escherichia coli Periplasmic Aldehyde Oxidoreductase Is an Exceptional Member of the Xanthine Oxidase Family of Molybdoenzymes
."
ACS Chemical Biology
. 11 (2016): 2923-2935.
Abstract
n/a
D
De Schutter, Amy, Hugo D. Correia, Diana M. Freire, Maria G. Rivas, Alberto Rizzi, Teresa Santos-Silva, Pablo J. Gonzalez, and Sabine Van Doorslaer.
"
Ligand Binding to Chlorite Dismutase from Magnetospirillum sp.
"
Journal of Physical Chemistry B
. 119 (2015): 13859-13869.
Abstract
n/a
F
Foti, Alessandro, Tobias Hartmann, Catarina Coelho, Teresa Santos-Silva, Maria Joao Romao, and Silke Leimkuehler.
"
Optimization of the Expression of Human Aldehyde Oxidase for Investigations of Single-Nucleotide Polymorphisms
."
Drug Metabolism and Disposition
. 44 (2016): 1277-1285.
Abstract
n/a
Freire, D. M., M. G. Rivas, A. M. Dias, A. T. Lopes, C. Costa, T. Santos-Silva, S. Van Doorslaer, and P. J. González.
"
The homopentameric chlorite dismutase from Magnetospirillum sp.
"
Journal of Inorganic Biochemistry
. 151 (2015): 1-9.
Abstract
n/a
H
Hettmann, T., R. A. Siddiqui, C. Frey, T. Santos-Silva, MJ Romão, and S. Diekmann.
"
Mutagenesis study on amino acids around the molybdenum centre of the periplasmic nitrate reductase from Ralstonia eutropha
."
Biochemical and Biophysical Research Communications
. 320 (2004): 1211-1219.
Abstract
n/a
Honzí?ek, J., A. Mukhopadhyay, T. Santos-Silva, MJ Romão, and C. C. Romão.
"
Ring-functionalized molybdenocene complexes
."
Organometallics
. 28 (2009): 2871-2879.
Abstract
n/a
M
Martins, Marta, Pedro V. Baptista, Ana Soraia Mendo, Claudia Correia, Paula Videira, Antonio S. Rodrigues, J. Muthukumaran, Teresa Santos-Silva, Ana Silva, Fatima M. C. Guedes da Silva, Joana Gigante, Antonio Duarte, Malgorzata Gajewska, and Alexandra R. Fernandes.
"
In vitro and in vivo biological characterization of the anti-proliferative potential of a cyclic trinuclear organotin(IV) complex
."
Molecular Biosystems
. 12 (2016): 1015-1023.
Abstract
n/a
Mehtab, S., G. Gon?alves, S. Roy, A. I. Tomaz, T. Santos-Silva, M. F. A. Santos, MJ Romão, T. Jakusch, T. Kiss, and JC Pessoa.
"
Interaction of vanadium(IV) with human serum apo-transferrin
."
Journal of Inorganic Biochemistry
. 121 (2013): 187-195.
Abstract
n/a
O
Otrelo-Cardoso, Ana Rita, Marcia Alexandra da Silva Correia, Viola Schwuchow, Dmitri I. Svergun, Maria Joao Romao, Silke Leimkuehler, and Teresa Santos-Silva.
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Structural Data on the Periplasmic Aldehyde Oxidoreductase PaoABC from Escherichia coli: SAXS and Preliminary X-ray Crystallography Analysis
."
International Journal of Molecular Sciences
. 15 (2014): 2223-2236.
Abstract
n/a
Otrelo-Cardoso, Ana Rita, Rashmi R. Nair, Marcia A. S. Correia, Maria G. Rivas, and Teresa Santos-Silva.
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TupA: A Tungstate Binding Protein in the Periplasm of Desulfovibrio alaskensis G20
."
International Journal of Molecular Sciences
. 15 (2014): 11783-11798.
Abstract
n/a
Otrelo-Cardoso, A. R., R. R. Nair, MAS Correia, R. S. C. Cordeiro, A. Panjkovich, D. I. Svergun, T. Santos-Silva, and M. G. Rivas.
"
Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20
."
Scientific Reports
. 7 (2017).
Abstract
n/a
Otrelo-Cardoso, Ana Rita, Viola Schwuchow, David Rodrigues, Eurico J. Cabrita, Silke Leimkuehler, Maria Joao Romao, and Teresa Santos-Silva.
"
Biochemical, Stabilization and Crystallization Studies on a Molecular Chaperone (PaoD) Involved in the Maturation of Molybdoenzymes
."
Plos One
. 9 (2014).
Abstract
n/a
P
Pessoa, Joao Costa, Eugenio Garribba, Marino F. A. Santos, and Teresa Santos-Silva.
"
Vanadium and proteins: Uptake, transport, structure, activity and function
."
Coordination Chemistry Reviews
. 301 (2015): 49-86.
Abstract
n/a
Pessoa, Joao Costa, Gisela Goncalves, Somnath Roy, Isabel Correia, Sameena Mehtab, Marino F. A. Santos, and Teresa Santos-Silva.
"
New insights on vanadium binding to human serum transferrin
."
Inorganica Chimica Acta
. 420 (2014): 60-68.
Abstract
n/a
R
Ribeiro, T., T. Santos-Silva, V. D. Alves, FMV Dias, A. S. Luís, JAM Prates, LMA Ferreira, MJ Romão, and CMGA Fontes.
"
Family 42 carbohydrate-binding modules display multiple arabinoxylan-binding interfaces presenting different ligand affinities
."
Biochimica et Biophysica Acta - Proteins and Proteomics
. 1804 (2010): 2054-2062.
Abstract
n/a
Romão, MJ, C. Coelho, T. Santos-Silva, A. Foti, M. Terao, E. Garattini, and S. Leimkühler.
"
Structural basis for the role of mammalian aldehyde oxidases in the metabolism of drugs and xenobiotics
."
Current Opinion in Chemical Biology
. 37 (2017): 39-47.
Abstract
n/a
S
Santos, M. F. A., J. D. Seixas, A. C. Coelho, A. Mukhopadhyay, P. M. Reis, MJ Romão, C. C. Romão, and T. Santos-Silva.
"
New insights into the chemistry of fac-[Ru(CO)3]2 + fragments in biologically relevant conditions: The CO releasing activity of [Ru(CO)3Cl2(1,3-thiazole)], and the X-ray crystal structure of its adduct with lysozyme
."
Journal of Inorganic Biochemistry
. 117 (2012): 285-291.
Abstract
n/a
Santos, Marino F. A., Isabel Correia, Ana R. Oliveira, Eugenio Garribba, Joao Costa Pessoa, and Teresa Santos-Silva.
"
Vanadium Complexes as Prospective Therapeutics: Structural Characterization of a V-IV Lysozyme Adduct
."
European Journal of Inorganic Chemistry
(2014): 3293-3297.
Abstract
n/a
Santos-Silva, Teresa, Correia MA, Otrelo-Cardoso AR, Schwuchow V, Sigfridsson Clauss KG, Haumann M, Romão MJ, Leimkühler S, and Santos-Silva T.
"
The Escherichia coli Periplasmic Aldehyde Oxidoreductase Is an Exceptional Member of the Xanthine Oxidase Family of Molybdoenzymes.
" (2016).
Abstract
n/a
Santos-Silva, T., JM Dias, G. Bourenkov, H. Bartunik, I. Moura, and MJ Romão.
"
Crystallization and preliminary X-ray diffraction analysis of the 16-haem cytochrome of Desulfovibrio gigas
."
Acta Crystallographica Section D: Biological Crystallography
. 60 (2004): 968-970.
Abstract
n/a
Santos-Silva, T., JM Dias, A. Dolla, M. - C. Durand, L. L. Gon?alves, J. Lampreia, I. Moura, and MJ Romão.
"
Crystal Structure of the 16 Heme Cytochrome from Desulfovibrio gigas: A Glycosylated Protein in a Sulphate-reducing Bacterium
."
Journal of Molecular Biology
. 370 (2007): 659-673.
Abstract
n/a
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Recent Publications
Imine Ligands Based on Ferrocene: Synthesis{,} Structural and Mossbauer Characterization and Evaluation as Chromogenic and Electrochemical Sensors for Hg+2
Mutagenesis study on amino acids around the molybdenum centre of the periplasmic nitrate reductase from Ralstonia eutropha
Superoxide reductase from the syphilis spirochete Treponema pallidum: Crystallization and structure determination using soft X-rays
Crystallization and preliminary X-ray diffraction analysis of the 16-haem cytochrome of Desulfovibrio gigas
The first crystal structure of class III superoxide reductase from Treponema pallidum
Ion jelly: A tailor-made conducting material for smart electrochemical devices
more