Publications

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Journal Article
Correia, H. D., J. Marangon, CD Brondino, JJG Moura, MJ Romão, P. J. González, and T. Santos-Silva. "Aromatic aldehydes at the active site of aldehyde oxidoreductase from Desulfovibrio gigas: Reactivity and molecular details of the enzyme-substrate and enzyme-product interaction." Journal of Biological Inorganic Chemistry. 20 (2015): 219-229. Abstract
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Correia, Hugo D., Jacopo Marangon, Carlos D. Brondino, Jose J. G. Moura, Maria J. Romao, Pablo J. Gonzalez, and Teresa Santos-Silva. "Aromatic aldehydes at the active site of aldehyde oxidoreductase from Desulfovibrio gigas: reactivity and molecular details of the enzyme-substrate and enzyme-product interaction (vol 20, pg 219, 2015)." Journal of Biological Inorganic Chemistry. 20 (2015): 231. Abstract
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Otrelo-Cardoso, Ana Rita, Viola Schwuchow, David Rodrigues, Eurico J. Cabrita, Silke Leimkuehler, Maria Joao Romao, and Teresa Santos-Silva. "Biochemical, Stabilization and Crystallization Studies on a Molecular Chaperone (PaoD) Involved in the Maturation of Molybdoenzymes." Plos One. 9 (2014). Abstract
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Seixas, J. D., A. Mukhopadhyay, T. Santos-Silva, L. E. Otterbein, D. J. Gallo, S. S. Rodrigues, B. H. Guerreiro, A. M. L. Gon?alves, N. Penacho, A. R. Marques, A. C. Coelho, P. M. Reis, MJ Romão, and C. C. Romão. "Characterization of a versatile organometallic pro-drug (CORM) for experimental CO based therapeutics." Dalton Transactions. 42 (2013): 5985-5998. Abstract
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Seixas, Joao D., Marino F. A. Santos, Abhik Mukhopadhyay, Ana C. Coelho, Patricia M. Reis, Luis F. Veiros, Ana R. Marques, Nuno Penacho, Ana M. L. Goncalves, Maria J. Romao, Goncalo J. L. Bernardes, Teresa Santos-Silva, and Carlos C. Romao. "A contribution to the rational design of Ru(CO)(3)Cl2L complexes for in vivo delivery of CO." Dalton Transactions. 44 (2015): 5058-5075. Abstract
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Santos-Silva, T., A. Mukhopadhyay, J. D. Seixas, G. J. L. Bernardes, C. C. Romão, and MJ Romão. "CORM-3 reactivity toward proteins: The crystal structure of a Ru(II) dicarbonyl-lysozyme complex." Journal of the American Chemical Society. 133 (2011): 1192-1195. Abstract
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Santos-Silva, T., JM Dias, A. Dolla, M. - C. Durand, L. L. Gon?alves, J. Lampreia, I. Moura, and MJ Romão. "Crystal Structure of the 16 Heme Cytochrome from Desulfovibrio gigas: A Glycosylated Protein in a Sulphate-reducing Bacterium." Journal of Molecular Biology. 370 (2007): 659-673. Abstract
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Santos-Silva, T., JM Dias, G. Bourenkov, H. Bartunik, I. Moura, and MJ Romão. "Crystallization and preliminary X-ray diffraction analysis of the 16-haem cytochrome of Desulfovibrio gigas." Acta Crystallographica Section D: Biological Crystallography. 60 (2004): 968-970. Abstract
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Watson, C., D. Niks, R. Hille, M. Vieira, B. Schoepp-Cothenet, AT Marques, MJ Romão, T. Santos-Silva, and J. M. Santini. "Electron transfer through arsenite oxidase: Insights into Rieske interaction with cytochrome c." Biochimica et Biophysica Acta - Bioenergetics. 1858 (2017): 865-872. Abstract
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Correia, MAS, A. R. Otrelo-Cardoso, V. Schwuchow, K. G. V. Sigfridsson Clauss, M. Haumann, MJ Romão, S. Leimkühler, and T. Santos-Silva. "The Escherichia coli Periplasmic Aldehyde Oxidoreductase Is an Exceptional Member of the Xanthine Oxidase Family of Molybdoenzymes." ACS Chemical Biology. 11 (2016): 2923-2935. Abstract
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Santos-Silva, Teresa, Correia MA, Otrelo-Cardoso AR, Schwuchow V, Sigfridsson Clauss KG, Haumann M, Romão MJ, Leimkühler S, and Santos-Silva T. "The Escherichia coli Periplasmic Aldehyde Oxidoreductase Is an Exceptional Member of the Xanthine Oxidase Family of Molybdoenzymes." (2016). Abstract
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Ribeiro, T., T. Santos-Silva, V. D. Alves, FMV Dias, A. S. Luís, JAM Prates, LMA Ferreira, MJ Romão, and CMGA Fontes. "Family 42 carbohydrate-binding modules display multiple arabinoxylan-binding interfaces presenting different ligand affinities." Biochimica et Biophysica Acta - Proteins and Proteomics. 1804 (2010): 2054-2062. Abstract
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Santos-Silva, T., J. Trincão, AL Carvalho, C. Bonifácio, F. Auchère, P. Raleiras, I. Moura, JJG Moura, and MJ Romão. "The first crystal structure of class III superoxide reductase from Treponema pallidum." Journal of Biological Inorganic Chemistry. 11 (2006): 548-558. Abstract
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Otrelo-Cardoso, A. R., R. R. Nair, MAS Correia, R. S. C. Cordeiro, A. Panjkovich, D. I. Svergun, T. Santos-Silva, and M. G. Rivas. "Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20." Scientific Reports. 7 (2017). Abstract
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Freire, D. M., M. G. Rivas, A. M. Dias, A. T. Lopes, C. Costa, T. Santos-Silva, S. Van Doorslaer, and P. J. González. "The homopentameric chlorite dismutase from Magnetospirillum sp." Journal of Inorganic Biochemistry. 151 (2015): 1-9. Abstract
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Vitor Rosa, Ana Gaspari, Filipe Folgosa, Cristina M. Cordas, Pedro Tavares, Teresa Santos-Silva, Sonia Barroso, and Teresa Aviles. "Imine Ligands Based on Ferrocene: Synthesis{,} Structural and Mossbauer Characterization and Evaluation as Chromogenic and Electrochemical Sensors for Hg+2." New J. Chem. (2018): -. AbstractWebsite

The compounds 1-naphthyliminoferrocene{,} 1{,} and 2-methyl-1-naphthyliminoferrocene{,} 2{,} were prepared by the reaction of ferrocenecarboxaldehyde and the corresponding amine{,} 1-naphthylamine and 2-methyl-1-naphthylamine with one drop of pyrrolidine as catalyst{,} in CH2Cl2{,} under inert atmosphere. The compounds were fully characterized by elemental analyses{,} matrix-assisted laser desorption/ionization - time-of-flight mass spectrometry (MALDI-TOF){,} FT-IR{,} 1H and 13C NMR as well as two-dimensional{,} NOESY{,} COSY and HSQC{,} NMR spectroscopy. Mossbauer spectroscopic studies were performed to characterize the iron species in both compounds. The solid-state molecular structures of compounds 1 and 2 were determined by single crystal X-ray diffraction. Analysis of the electrochemical behaviour of complexes 1 and 2 was performed by cyclic and square wave voltammetry. Compounds 1 and 2 were tested as chromogenic and electrochemical sensors for Hg2+.

Martins, Marta, Pedro V. Baptista, Ana Soraia Mendo, Claudia Correia, Paula Videira, Antonio S. Rodrigues, J. Muthukumaran, Teresa Santos-Silva, Ana Silva, Fatima M. C. Guedes da Silva, Joana Gigante, Antonio Duarte, Malgorzata Gajewska, and Alexandra R. Fernandes. "In vitro and in vivo biological characterization of the anti-proliferative potential of a cyclic trinuclear organotin(IV) complex." Molecular Biosystems. 12 (2016): 1015-1023. Abstract
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Mehtab, S., G. Gon?alves, S. Roy, A. I. Tomaz, T. Santos-Silva, M. F. A. Santos, MJ Romão, T. Jakusch, T. Kiss, and JC Pessoa. "Interaction of vanadium(IV) with human serum apo-transferrin." Journal of Inorganic Biochemistry. 121 (2013): 187-195. Abstract
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Santos-Silva, Teresa, Pessoa JC, Correia I, Chorna I, Cavaco I, Roy S, Kuznetsov ML, Ribeiro N, Justino G, Marques F, Silva TS, Santos M, Santos HM, Capelo JL, and Doutch J. "Interaction of VIVO(acac)2 with human serum transferrin and albumin." (2017). AbstractWebsite
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Vidinha, P., N. M. T. Louren?o, C. Pinheiro, A. R. Brás, T. Carvalho, T. Santos-Silva, A. Mukhopadhyay, MJ Romão, J. Parola, M. Dionisio, J. M. S. Cabral, CAM Afonso, and S. Barreiros. "Ion jelly: A tailor-made conducting material for smart electrochemical devices." Chemical Communications (2008): 5842-5844. Abstract
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Santos-Silva, Teresa, Marangon J, Correia HD, Brondino CD, Moura JJ, Romão MJ, González PJ, and Santos-Silva T. "Kinetic and structural studies of aldehyde oxidoreductase from Desulfovibrio gigas reveal a dithiolene-based chemistry for enzyme activation and inhibition by H(2)O(2)." (2013). AbstractWebsite
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Santos-Silva, T., F. Ferroni, A. Thapper, J. Marangon, P. J. González, A. C. Rizzi, I. Moura, JJG Moura, MJ Romão, and CD Brondino. "Kinetic, structural, and EPR studies reveal that aldehyde oxidoreductase from Desulfovibrio gigas does not need a sulfido ligand for catalysis and give evidence for a direct Mo-C interaction in a biological system." Journal of the American Chemical Society. 131 (2009): 7990-7998. Abstract
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De Schutter, Amy, Hugo D. Correia, Diana M. Freire, Maria G. Rivas, Alberto Rizzi, Teresa Santos-Silva, Pablo J. Gonzalez, and Sabine Van Doorslaer. "Ligand Binding to Chlorite Dismutase from Magnetospirillum sp." Journal of Physical Chemistry B. 119 (2015): 13859-13869. Abstract
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Hettmann, T., R. A. Siddiqui, C. Frey, T. Santos-Silva, MJ Romão, and S. Diekmann. "Mutagenesis study on amino acids around the molybdenum centre of the periplasmic nitrate reductase from Ralstonia eutropha." Biochemical and Biophysical Research Communications. 320 (2004): 1211-1219. Abstract
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Santos, M. F. A., J. D. Seixas, A. C. Coelho, A. Mukhopadhyay, P. M. Reis, MJ Romão, C. C. Romão, and T. Santos-Silva. "New insights into the chemistry of fac-[Ru(CO)3]2 + fragments in biologically relevant conditions: The CO releasing activity of [Ru(CO)3Cl2(1,3-thiazole)], and the X-ray crystal structure of its adduct with lysozyme." Journal of Inorganic Biochemistry. 117 (2012): 285-291. Abstract
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