@article {5358,
	title = {Synthesis of catecholamine conjugates with nitrogen-centered bionucleophiles},
	journal = {Bioorganic Chemistry},
	volume = {44},
	year = {2012},
	note = {<p>Times Cited: 0 Siopa, Filipa Pereira, Alice S. Ferreira, Luisa M. Matilde Marques, M. Branco, Paula S.</p>
},
	pages = {19-24},
	type = {Journal Article},
	abstract = {<p>The enzymatic (tyrosinase) and chemical (NaIO4, Ag2O or Fremys{\textquoteright}s salt) oxidation of biologically relevant catecholamines, such as dopamine (DA), N-acetyldopamine (NADA) and the Ecstasy metabolites (alpha-MeDA and N-Me-alpha-MeDA) generates the corresponding o-quinone which can be trapped with nitrogen bionucleophiles such as N-acetyl-histidine and imidazole in a regioselective reaction that takes place predominantly at the 6-position of the catecholamine. (C) 2012 Elsevier Inc. All rights reserved.</p>
},
	issn = {0045-2068},
	doi = {10.1016/j.bioorg.2012.05.002},
	url = {<Go to ISI>://WOS:000313902300003},
	author = {Siopa, F. and Pereira, AS and Ferreira, LM and Marques, M. M. and Branco, P.S.}
}
