An integrated approach for assessing the bioreceptivity of glazed tiles to phototrophic microorganisms - Coutinho, M. L.; Miller, A. Z.; Rogerio-Candelera, M.A.; Mirão, J; Cerqueira Alves, L; Veiga, JP; Águas, H.; Pereira, S.; Lyubchyk, A; Macedo, MF (Biofouling, 2016)
© 2016 Taylor {&} Francis.A laboratory-based methodology was designed to assess the bioreceptivity of glazed tiles. The experimental set-up consisted of multiple steps: manufacturing of pristine and artificially aged glazed tiles, enrichment of phototrophic microorganisms, inoculation of phototrophs on glazed tiles, incubation under optimal conditions and quantification of biomass. In addition, tile intrinsic properties were assessed to determine which material properties contributed to tile bioreceptivity. Biofilm growth and biomass were appraised by digital image analysis, colorimetry and chlorophyll a analysis. SEM, micro-Raman and micro-particle induced X-ray emission analyses were carried out to investigate the biodeteriorating potential of phototrophic microorganisms on the glazed tiles. This practical and multidisciplinary approach showed that the accelerated colonization conditions allowed different types of tile bioreceptivity to be distinguished and to be related to precise characteristics of the material. Aged tiles showed higher bioreceptivity than pristine tiles due to their higher capillarity and permeability. Moreover, biophysical deterioration caused by chasmoendolithic growth was observed on colonized tile surfaces.
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Keywords: bioreceptivity; ceramic; Glazed; [biodeterioration

Introducing graded meshes in the numerical approximation of distributed-order diffusion equations - M. L. Morgado; M. Rebelo (NUMERICAL COMPUTATIONS: THEORY AND ALGORITHMS (NUMTA–2016), 2016)

The Jacobi Collocation Method for a Class of Nonlinear Volterra Integral Equations with Weakly Singular Kernel - Allaei, S. S.; Diogo, T.; M. Rebelo (Journal of Scientific Computing, 2016)

Machine learning approach to forecasting urban pollution: a case study of Quito, Ecuador - Rybarczyk; Y.; Zalakeviciute R. (IEEE ETCM, 2016)

A Multichannel Time-Frequency and Multi-Wavelet Toolbox for Uterine Electromyography Processing and Visualisation - Batista, AG; Najdi, S.; Godinho, D. M.; Serrano, F.; Ortigueira, M.D.; Rato, R.T. (Computers in Biology and Medicine, 2016)

Numerical solution for diffusion equations with distributed order in time using a Chebyshev collocation method - M. L. Morgado; M. Rebelo; Ferrás, L. L.; Ford, N. (Applied Numerical Mathematics, 2016)

O jogo como promotor da comunicação e aprendizagem matemática [Games to promote communication and mathematical learning] - S. Lopes; Rocha, H. (XXVII SIEM, 2016)
Games are commonly appointed as a methodological tool capable of promoting students’ effective learning. In this context, this study intends to analyze the impact of mathematical discussions developed while playing a polynomial game. Namely it intends to analyze the impact on the consolidation of mathematical concepts previously worked in the classroom and on the communications skills. Two case studies where developed involving 10th grade students. Data gathering was based on direct observation and an inquiry. The main conclusions suggest that the game encouraged the discussion about the mathematical contents and therefore promoted the development of the mathematical discourse. Besides that, it allowed a deeper apprehension of mathematical concepts, and the overcome of some difficulties.

O raciocínio dedutivo de alunos do 10.º ano de escolaridade [The deductive reasoning of students in the 10th grade] - Coelho, E.; Rocha, H. (XXVII SIEM, 2016)
Deductive reasoning, being central in mathematics, is also usually a source of difficulties for students, more used to the empirical approaches. In this study we focus on mathematical proof and we try to give attention to how this kind of reasoning is envisaged by the students, to the options they assume when asked to develop a deductive reasoning and to the factors affecting the implementation of this kind of reasoning. The study follows a qualitative and interpretative methodological approach, including the completion of two case studies of students of the 10th grade. Data were collected in work sessions and through interviews. The main findings point to a devaluation of mathematical proof and a strong preference for empirical approaches. Yet students show ability to develop different approaches. The preference for the mathematical subject and the attention given in class to the deduction work, appears to be relevant factors when considering the students' ability to develop a deductive reasoning when involved on a mathematical proof.

Punching behaviour of RC flat slabs under reversed horizontal cyclic loading - Almeida, André F.O.; Inácio, Micael M.G.; Lúcio, Válter J.G.; Ramos, António Pinho (Engineering Structures, 2016)
The aim of this work is to study the behaviour of reinforced concrete flat slab structures under combined vertical and horizontal cyclic loading. A total of five specimens were cast and tested: a control specimen was punched without eccentricity, one specimen was tested under constant vertical loading and monotonically increased eccentricity until failure and the remaining three were tested under constant vertical load, at different shear ratios, and cyclic horizontal loading with increasing horizontal drift ratios. All slabs were similar, measuring 4.25×1.85×0.15m3. The reinforced concrete slab specimens were connected to two steel half columns by 0.25×0.25m2 rigid steel plates, prestressed against the slab using steel bolts, to ensure monolithic behaviour. The cyclic tests were performed using an innovative test setup that allows bending moment redistribution, line of inflection mobility, assures equal vertical displacements at the North-South borders and symmetrical shear forces. Results show that cyclic horizontal actions are very harmful to the slab–column connection, resulting in low horizontal drifts and energy dissipation.
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Keywords: Cyclic horizontal action; Flat slab; Punching

Punching of Flat Slabs under Reversed Horizontal Cyclic Loading - António Ramos; Marreiros, Rui; Almeida, André; Isufi, Brisid; Inácio, Micael (ACI Fall Convention 2016, 2016)
Flat slab structures are a very common structural solution nowadays, due to their architectural and economic advantages. However, flat slab-column connections may be vulnerable to punching failure, especially in an event of an earthquake, with potentially high human and economic losses. This type of structural solution is adequately covered by design codes and recommendations in North America, due to a large amount of experimental research carried out. In Europe the situation is different, missing specific guidance to flat slab design under earthquake action in most European codes. The ACI 318-14 prescriptive approach to the gravity shear ratio-drift ratio relationship shows good agreement with experimental results. Following a similar approach and, based in a databank containing cyclic horizontally loaded tests of slab-column connections found in literature, proposals are made applicable to EC2 and MC2010.
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Keywords: drift; Flat slabs; gravity shear ratio; horizontal cyclic loading; performance based design; Punching

Reforço ao punçoamento de lajes fungiformes com lâmina complementar de betão - Hugo Fernandes; Válter, Lúcio; Ramos, António Pinho (Encontro Nacional Betão Estrutural 2016, 2016)
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Smart optically active VO nanostructured layers applied in roof-type ceramic tiles for energy efficiency - A Gonçalves; J. Resende; Marques, A C; Pinto, JV; Nunes, D.; A. Marie; R. Gonçalves; Pereira, L.; Martins, R.; Fortunato, E. (Solar Energy Materials & Solar Cells, 2016)

Strengthening of concrete Flat Slabs with an Overlaid Reinforced Concrete Layer - Hugo Fernandes; Válter Lúcio; António Ramos (fib Symposium 2016 - Performance-based Approaches for Concrete Structures, 2016)

Synthesis, Characterization, Antimicrobial and Antitumor Activities of Sucrose Octa(N-ethyl)carbamate. - C.D. Raposo; K. T. Petrova; M. T. Barros; R.C. Calhelha; M. Sokovic; I.C.F.R. Ferreira (Med. Chem, 2016)

Teachers’ use of the different representations in a context of technology integration - Rocha, H. (Proceddings of 13th International Congress on Mathematical Education, 2016)
This study focus on the different representations provided by graphing calculators, intending to characterize how the teacher uses and integrates them on the process of teaching and learning functions at the secondary level. The methodology adopted is qualitative and interpretative, undertaking two case studies. The main conclusions point to different levels of flexibility in the use of the different representations depending on the teacher, but suggest a strong preference for the graphical and the algebraic representations, a use of the numerical representation based on the graph of the function and a total lack of use of the tabular representation.

Teacher’s representational fluency in a context of technology use - Rocha, H. (Teaching Mathematics and its Applications, 2016)
This study focuses on teacher’s Knowledge for Teaching Mathematics with Technology (KTMT), paying a special attention to teacher’s representational fluency. It intends to characterize how the teacher uses and integrates the different representations provided by the graphing calculator on the process of teaching and learning functions at the high school level. Specifically, it intends to understand the balance established between the use of the different representations, and the way these representations are articulated. The study adopts a qualitative approach undertaking one teacher case study. Data were collected for two school years, at 10th and 11th grades, and included class observation, semi-structured interviews and documents gathering. Data analysis was mainly descriptive and interpretive in nature, considering the problem under study. The conclusions reached reveal an active use of the graphical and algebraic representations and a scarce use of the tabular representation. The lack of balance on the use of representations also includes the work within a representation. In this case the graphical representation is the only one that was explored. The conclusions also indicate a flexible articulation between the two representations usually used. It was possible to identify different patterns on the use of the representations and a frequent use of an interactive approach, marked by repeated alternations between representations. Globally, this study emphasizes teacher’s KTMT and raises questions about the impact of technology on teacher´s representational fluency and about the difference between a numerical and a tabular representation.

Uma proposta para análise do Conhecimento para Ensinar Matemática com a Tecnologia [A proposal to analyze the teacher's Knowledge for Teaching Mathematics with Technology] - Rocha, H. (XXVII SIEM, 2016)
The teacher’s knowledge has long been viewed as a strong influence on the students’ learning. Several authors have sought to develop procedures to assess this knowledge, but this has proved to be a complex task. In this paper I present an outline of a conceptualization to analyze the teacher's knowledge, based on the model of the Knowledge for Teaching Mathematics with Technology (KTMT) and a set of tasks. These tasks are chosen by the teacher among the ones he prepared for his students taking into account the potential of the tasks to take advantage of the technology’s potential. The analyze of the teacher’s KTMT is based on the characteristics of the tasks chosen by the teacher; the balance established between the representations provided by the technology that the tasks advocate; the way how the tasks pay attention to the new issue of seeking for a suitable viewing window; and also the way how the tasks take into account the expectable difficulties of the students in the process of looking for the window.

The use of graphing calculator in the exploration of nonlinear continuous models - Viseu, F.; Campos, S.; Fernandes, J.; Rocha, H. (Revemat, 2016)
The integration of the graphing calculator in mathematical activity encourages students to express many of their processes and ways of thinking. Since some of the activities at the high school level are carried out with the graphing calculator, we intend to investigate the contribution of this resource to promote the learning of nonlinear continuous models in the 11th grade. By adopting a qualitative methodology, we collected and analysed the students‟ writing productions. At first, students used to present the information given by the calculator with no justification. As they acquire skills in the use of this resource, they usually set up the viewing window in order to visualize the graphical representations of functions that model the problem situation they are working on and also relate the different existing menus in the study of those functions characteristics. Such procedures make students to present the data collected in the calculator with a justification of their arguments and a validation of their conjectures.

Using games for the phonetics awareness of children with Down syndrome - Simão; J.; Cotrim; L.; Condeço; T.; Cardoso; T.; Palha; M.; Rybarczyk; Y.; et al. (6th EAI International Conference on Serious Games, Interaction and Simulation, 2016)

Using Games for the Phonetics Awareness of Children with Down Syndrome - Simao, José; Cotrim, Luisa; Condeco, Teresa; Cardoso, Tiago; Palha, Miguel; Rybarczyk, Yves; Barata, José (International Conference on Serious Games, Interaction and Simulation, 2016)
Computers and technology can play a key role in supporting learning, namely for students with special educational needs. Nevertheless, despite the emphasis the society puts on the use of technology and its fast proliferation in the area of education, few initiatives focus on the specific needs of children with disabilities. Motivated by this gap, this research work proposes a computer assisted education application that targets to teach talking and reading through games. The work described herein was carried out in close cooperation with - , a child-care institution that works with children with distinct growth disorders, namely the Down syndrome.
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WebLisling: uma plataforma terapêutica baseada na web para a reabilitação de doentes afásicos - Rybarczyk; Y.; Gonçalves M.J. (IEEE Latin America Transactions, 2016)

Development and characterization of novel auxetic structures based on re-entrant hexagon design produced from braided composites - P. Subramani; Sohel Rana; Bahman Ghiassi; Raul Fangueiro; Daniel V. Oliveira; Paulo B. Lourenco; Jose Xavier (Composites Part B: Engineering, 2016)
Abstract This paper reports the first attempt of developing macro-scale auxetic structures based on re-entrant hexagon design from braided composite materials for civil engineering applications. Braided composite rods (BCRs) were produced and arranged as longitudinal and horizontal elements to produce three types of auxetic structures: (1) basic re-entrant hexagon structure, (2) basic structure modified by adding straight longitudinal elements and (3): structure-2 modified by changing structural angle. The influence of various material and structural parameters as well as structure type on Poisson's ratio and tensile properties was thoroughly investigated. The auxetic behaviour was found to strongly depend on the structural angle and straight elements, resulting in lower auxeticity with lower angles and in presence of straight elements. Material parameters influenced the auxetic behaviour to a lesser extent and a decrease in auxetic behaviour was noticed with increase in core fibre linear density and using stiffer fibres such as carbon. The reverse effect was observed in case of tensile strength and work of rupture. Among these structures, structure-3 exhibited good auxetic behaviour, balanced tensile properties, and high energy absorption capacity and their auxetic behaviour could be well predicted with the developed analytical model. Therefore, these novel structures present good potential for strengthening of civil structures.
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Keywords: A. Smart materials; B. Mechanical properties; C. Analytical modelling; D. Mechanical testing; E. Braiding

Electric Vehicle Battery Charger: Wireless Power Transfer System Controlled by Magnetic Core Reactor - Luis Romba; Stan Valtchev; Melicio, R. (CETC2016 - Conference on Electronics, Telecommunications and Computers, Proceedings, 2016)
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Electromagnetic Emissions from Wireless Power Transfer System - Baikova, E. N.; Romba, L. F.; Stan Valtchev; Rui Melício; Fernão Pires, V. (CETC2016 - Conference on Electronics, Telecommunications and Computers, Proceedings, 2016)
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The Escherichia coli Periplasmic Aldehyde Oxidoreductase Is an Exceptional Member of the Xanthine Oxidase Family of Molybdoenzymes - Correia, MAS; Otrelo-Cardoso, A.R.; Schwuchow, V; Sigfridsson Clauss, K.G.V.; Haumann, M.; Romão, MJ; Leimkühler, S; Santos-Silva, T (ACS Chemical Biology, 2016)
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Genetic Diversity and Physiological Performance of Portuguese Wild Beet (Beta vulgaris spp. maritima) from Three Contrasting Habitats - Ribeiro, IC; Pinheiro, C.; Ribeiro, C. M.; Veloso, M. M.; Simoes-Costa, M. C.; Evaristo, I.; Paulo, O. S.; Ricardo, C. P. (Frontiers in Plant Science, 2016)
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Hybrid Microfluidic Platform for Multifactorial Analysis Based on Electrical Impedance, Refractometry, Optical Absorption and Fluorescence - Pereira, Fábio M; Bernacka-Wojcik, Iwona; Ribeiro, Rita S Rodrigues; Lobato, Maria Teresa; Fortunato, Elvira; Martins, Rodrigo; Igreja, Rui; Jorge, Pedro AS; Águas, Hugo; Oliva, Abel Martin Gonzalez (Micromachines, 2016)
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Hybrid Microfluidic Platform for Multifactorial Analysis Based on Electrical Impedance, Refractometry, Optical Absorption and Fluorescence - Pereira, Fabio M.; Bernacka-Wojcik, Iwona; Ribeiro, Rita S Rodrigues; Lobato, Maria Teresa; Fortunato, Elvira; Martins, Rodrigo; Igreja, Rui; Jorge, Pedro AS; Aguas, Hugo; Oliva, Abel Martin Gonzalez (Micromachines, 2016)
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Improving positive and negative bias illumination stress stability in parylene passivated IGZO transistors - Kiazadeh, A.; Gomes, H. L.; Barquinha, P.; J. Martins; Rovisco, A.; Pinto, JV; Martins, R.; Fortunato, E. (Applied Physics Letters, 2016)
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In vitro and in vivo biological characterization of the anti-proliferative potential of a cyclic trinuclear organotin(IV) complex - Martins, Marta; Baptista, Pedro V.; Mendo, Ana Soraia; Correia, Claudia; Videira, Paula; Rodrigues, Antonio S.; Muthukumaran, J.; Santos-Silva, Teresa; Silva, Ana; Guedes da Silva, M. Fatima C.; Gigante, Joana; Duarte, Antonio; et al. (Molecular Biosystems, 2016)
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Influence of Channel Length Scaling on InGaZnO TFTs Characteristics: Unity Current-Gain Cutoff Frequency, Intrinsic Voltage-Gain, and On-Resistance - Bahubalindruni, P.G.; Kiazadeh, A.; Sacchetti, A.; J. Martins; Rovisco, A.; Tavares, V.G.; Martins, R.; Fortunato, E.; Barquinha, P. (Journal of Display Technology, 2016)
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An integrated approach for assessing the bioreceptivity of glazed tiles to phototrophic microorganisms - Coutinho, M. L.; Miller, A. Z.; Rogerio-Candelera, Miguel A.; Mirão, J; Cerqueira Alves, L; Veiga, João P; Águas, H.; Pereira, S{\'ılvia; Lyubchyk, A; Macedo, MF (Biofouling, 2016)
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Optimization of the Expression of Human Aldehyde Oxidase for Investigations of Single-Nucleotide Polymorphisms - Foti, Alessandro; Hartmann, Tobias; Coelho, Catarina; Santos-Silva, Teresa; Romao, Maria Joao; Leimkuehler, Silke (Drug Metabolism and Disposition, 2016)
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Photography-based taxonomy is inadequate, unnecessary, and potentially harmful for biological sciences - Ceríaco, L.M.P.; Gutiérrez, E.E.; Dubois, A.; Abdala, C.S.; Alqarni, A.S.; Adler, K.; Adriano, E.A.; Aescht, E.; Agarwal, I.; Agatha, S.; Agosti, D.; Aguiar, A.J.C.; et al. (Zootaxa, 2016)
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Preface of the - Coelho, Carlos A; Marques,Filipe J.; Richter, Wolf-Dieter (AIP Conference Proceedings, 2016)
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Primitive groups, graph endomorphisms and synchronization - Araújo, João; Bentz, Wolfram; Cameron, Peter J.; Royle, Gordon; Schaefer, Artur (Proc. Lond. Math. Soc. (3), 2016)
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Primitive groups, graph endomorphisms and synchronization - Araújo, João; Bentz, Wolfram; Cameron, Peter J.; Royle, Gordon; Schaefer, Artur (Proc. Lond. Math. Soc. (3), 2016)
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Robot 2015: Second Iberian Robotics Conference - B. J. Guerreiro; Silvestre, C.; R. Cunha (Springer, 2016)
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Robot 2015: Second Iberian Robotics Conference - B. J. Guerreiro; Silvestre, C.; R. Cunha (Springer, 2016)
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A robótica como ferramenta coadjuvante na formação e reabilitação de crianças com NEE Robotics as an auxiliary tool in the education and rehabilitation of children with SEN - Conchinha, Cristina; Rodrigues, Andiara Catarina Honório; Nogueira, Alessandra Pires; Correia de Freitas, João (2016)
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Selection of a data exchange format for industry 4.0 manufacturing systems - {Peres, Ricardo Silva; Parreira-Rocha, Mafalda; Andre Dionisio Rocha; Barbosa, José; Leitão, Paulo; Barata, José (Industrial Electronics Society, IECON 2016-42nd Annual Conference of the IEEE, 2016)
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Sensing and tuning microfiber chirality with nematic chirogyral effect - Čopar, Simon; Seč, David; Aguirre, Luis E; Almeida, Pedro L; Dazza, Mallory; Ravnik, Miha; Godinho, Maria H; Pieranski, Pawel; Žumer, Slobodan (Physical Review E, 2016)
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Sensing surface morphology of biofibers by decorating spider silk and cellulosic filaments with nematic microdroplets - Aguirre, Luis E; de Oliveira, Alexandre; Seč, David; Čopar, Simon; Almeida, Pedro L; Ravnik, Miha; Godinho, Maria Helena; Žumer, Slobodan (Proceedings of the National Academy of Sciences, 2016)
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Three-phase magnetic field system for wireless energy transfer - Romba, L.F.; SS Valtchev; Melicio, R. (2016 International Symposium on Power Electronics, Electrical Drives, Automation and Motion, SPEEDAM 2016, 2016)
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Wireless Energy Transfer with Three-Phase Magnetic Field System: Experimental Results - Luis Romba; Stan Valtchev; Rui Melício (2016)
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Sem PDF.; International Conference on Renewable Energies and Power Quality , ICREPQ’16 ; Conference date: 04-05-2016 Through 06-05-2016

Wireless Energy Transfer with Three-Phase Magnetic Field System: Experimental Results - Luis Romba; Stan Valtchev; Rui Melício (2016)
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Sem PDF.; International Conference on Renewable Energies and Power Quality , ICREPQ’16 ; Conference date: 04-05-2016 Through 06-05-2016

{Dissolution enhancement of active pharmaceutical ingredients by therapeutic deep eutectic systems} - Aroso, Ivo M; Silva, João C.; Mano, Francisca; Ferreira, Ana S. D.; Dionísio, Madalena; Isabel Sá-Nogueira; Barreiros, Susana; Reis, Rui L; Paiva, Alexandre; Duarte, Ana Rita C (European Journal of Pharmaceutics and Biopharmaceutics, 2016)
A therapeutic deep eutectic system (THEDES) is here defined as a deep eutectic solvent (DES) having an active pharmaceutical ingredient (API) as one of the components. In this work, THEDESs are proposed as enhanced transporters and delivery vehicles for bioactive molecules. THEDESs based on choline chloride (ChCl) or menthol conjugated with three different APIs, namely acetylsalicylic acid (AA), benzoic acid (BA) and phenylacetic acid (PA), were synthesized and characterized for thermal behaviour, structural features, dissolution rate and antibacterial activity. Differential scanning calorimetry and polarized optical microscopy showed that ChCl:PA (1:1), ChCl:AA (1:1), menthol:AA (3:1), menthol:BA (3:1), menthol:PA (2:1) and menthol:PA (3:1) were liquid at room temperature. Dissolution studies in PBS led to increased dissolution rates for the APIs when in the form of THEDES, compared to the API alone. The increase in dissolution rate was particularly noticeable for menthol-based THEDES. Antibacterial activity was assessed using both Gram-positive and Gram-negative model organisms. The results show that all the THEDESs retain the antibacterial activity of the API. Overall, our results highlight the great potential of THEDES as dissolution enhancers in the development of novel and more effective drug delivery systems.
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Keywords: Drug solubility; Green technologies; Pharmaceutical and biomedical applications; Therapeutic deep eutectic systems

{Drug-eluting biodegradable ureteral stent: New approach for urothelial tumors of upper urinary tract cancer} - Barros, A.A.; Browne, S.; Oliveira, C.; Lima, E.; Duarte, A.R.C.; Healy, K.E.; Reis, R.L. (International Journal of Pharmaceutics, 2016)
© 2016 Elsevier B.V. Upper urinary tract urothelial carcinoma (UTUC) accounts for 5–10{%} of urothelial carcinomas and is a disease that has not been widely studied as carcinoma of the bladder. To avoid the problems of conventional therapies, such as the need for frequent drug instillation due to poor drug retention, we developed a biodegradable ureteral stent (BUS) impregnated by supercritical fluid CO 2 (scCO 2 ) with the most commonly used anti-cancer drugs, namely paclitaxel, epirubicin, doxorubicin, and gemcitabine. The release kinetics of anti-cancer therapeutics from drug-eluting stents was measured in artificial urine solution (AUS). The in vitro release showed a faster release in the first 72 h for the four anti-cancer drugs, after this time a plateau was achieved and finally the stent degraded after 9 days. Regarding the amount of impregnated drugs by scCO 2 , gemcitabine showed the highest amount of loading (19.57 $μ$g drug /mg polymer: 2{%} loaded), while the lowest amount was obtained for paclitaxel (0.067 $μ$g drug /mg polymer : 0.01{%} loaded). A cancer cell line (T24) was exposed to graded concentrations (0.01–2000 ng/ml) of each drugs for 4 and 72 h to determine the sensitivities of the cells to each drug (IC 50 ). The direct and indirect contact study of the anti-cancer biodegradable ureteral stents with the T24 and HUVEC cell lines confirmed the anti-tumoral effect of the BUS impregnated with the four anti-cancer drugs tested, reducing around 75{%} of the viability of the T24 cell line after 72 h and demonstrating minimal cytotoxic effect on HUVECs.
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Keywords: Anti-cancer drugs; Biodegradable polymers; supercritical fluid technology; T24 cell line; Upper tract urothelial carcinoma; ureteral stents

{Extraction of Collagen/Gelatin from the Marine Demosponge Chondrosia reniformis (Nardo, 1847) Using Water Acidified with Carbon Dioxide - Process Optimization} - Silva, João C.; Barros, Alexandre A.; Aroso, Ivo M; Fassini, Dario; Silva, Tiago H.; Reis, Rui L; Duarte, Ana Rita C (Industrial and Engineering Chemistry Research, 2016)
Marine sponges are a rich source of natural bioactive compounds. One of the most abundant valuable products is collagen/gelatin, which presents an interesting alternative source for pharmaceutical and biomedical applications. We have previously proposed an innovative green technology for the extraction of collagen/gelatin from marine sponges based in water acidified with carbon dioxide. In this work, we have optimized the process operating conditions toward high yields and collagen quality as well as to reduce extraction procedure duration and energy consumption. The process extraction efficiency is higher than 50{%}, corresponding to a yield of approximately 10{%} of the sponge dry mass, obtained for mild operating conditions of 10 bar and 3 h. The extracted material was characterized by scanning electron microscopy (SEM), rheology, Fourier transformed infrared spectroscopy (FTIR), circular dichroism (CD), amino acid analysis, and SDS-PAGE. The extracts were found to be composed of highly pure mixtures of co...
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{From honeycomb- to microsphere-patterned surfaces of poly(lactic acid) and a starch-poly(lactic acid) blend via the breath figure method.} - Duarte, Ana Rita C; Maniglio, Devid; Sousa, Nuno; João F. Mano; Reis, Rui L; Migliaresi, Claudio (Journal of applied biomaterials {&} functional materials, 2016)
BACKGROUND This study investigated the preparation of ordered patterned surfaces and/or microspheres from a natural-based polymer, using the breath figure and reverse breath figure methods. METHODS Poly(D,L-lactic acid) and starch poly(lactic acid) solutions were precipitated in different conditions - namely, polymer concentration, vapor atmosphere temperature and substrate - to evaluate the effect of these conditions on the morphology of the precipitates obtained. RESULTS The possibility of fine-tuning the properties of the final patterns simply by changing the vapor atmosphere was also demonstrated here using a range of compositions of the vapor phase. Porous films or discrete particles are formed when the differences in surface tension determine the ability of polymer solution to surround water droplets or methanol to surround polymer droplets, respectively. In vitro cytotoxicity was assessed applying a simple standard protocol to evaluate the possibility to use these materials in biomedical applications. Moreover, fluorescent microscopy images showed a good interaction of cells with the material, which were able to adhere on the patterned surfaces after 24 hours in culture. CONCLUSIONS The development of patterned surfaces using the breath figure method was tested in this work for the preparation of both poly(lactic acid) and a blend containing starch and poly(lactic acid). The potential of these films to be used in the biomedical area was confirmed by a preliminary cytotoxicity test and by morphological observation of cell adhesion.
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Keywords: biomaterials; breath figures; lactic acid; natural polymers; patterns; poly; starch

{Hybrid Alginate-Based Cryogels for Life Science Applications} - Barros, A.; Quraishi, S.; Martins, M; Gurikov, P.; Subrahmanyam, R.; Smirnova, I.; Duarte, A.R.C.; Reis, R.L. (Chemie-Ingenieur-Technik, 2016)
© 2016 WILEY-VCH Verlag GmbH {&} Co. KGaA, Weinheim. This work presents a novel route toward porous scaffolds for tissue engineering and regenerative medicine (TERM) applications. Hybrid cryogels with gelatin, gellan gum, carboxymethylcellulose, and lignin were prepared by a two-step process. Textural properties of the cryogels were analyzed by SEM and micro-computed tomography. The results indicated that rapid freezing retained sample shape and yielded macroporous materials. The mechanical properties of the cryogels were characterized in compression mode. Cytotoxicity studies indicated that the hybrid-alginate cryogels did not present cytotoxicity and have the potential to be used in TERM.
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Keywords: Alginate; Cryogel; Freeze-drying

{In vitro bioactivity studies of ceramic structures isolated from marine sponges} - Barros, A.A.; Aroso, I.M.; Silva, T.H.; Mano, J.F.; Duarte, A.R.C.; Reis, R.L. (Biomedical Materials (Bristol), 2016)
© 2016 IOP Publishing Ltd. In this work, we focused on the potential of bioceramics from different marine sponges - namely Petrosia ficiformis, Agelas oroides and Chondrosia reniformis - for novel biomedical/industrial applications. The bioceramics from these sponges were obtained after calcination at 750 °C for 6 h in a furnace. The morphological characteristics were evaluated by scanning electron microscopy (SEM). The in vitro bioactivity of the bioceramics was evaluated in simulated body fluid (SBF) after 14 and 21 d. Observation of the bioceramics by SEM after immersion in SBF solution, coupled with spectroscopic elemental analysis (EDS), showed that the surface morphology was consistent with a calcium-phosphate (Ca/P) coating, similar to hydroxyapatite crystals (HA). Evaluation of the characteristic peaks of Ca/P crystals by Fourier transform infrared spectroscopy and x-ray diffraction further confirmed the existence of HA. Cytotoxicity studies were carried out with the different ceramics and these were compared with a commercially available Bioglass ® . In vitro tests demonstrated that marine bioceramics from these sponges are non-cytotoxic and have the potential to be used as substitutes for synthetic Bioglass ® .
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Keywords: Bioactive glass; Bioactivity; Bioceramics; Hydroxyapatite; Marine sponge

{Multiple Source Phototherapy in Breast Cancer: A Viability Study} - Lopes, A.; Gabriel, A; Machado, J; Ribeiro, P; Gomes, R; Coelho, João M P; Silva, C O; Reis, C P; J P Santos; Vieira, P. (9th International Conference on Biomedical Electronics and Devices, 2016)
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{Nuclear astrophysics with radioactive ions at FAIR} - Reifarth, R; Altstadt, S; Göbel, K; Heftrich, T; Heil, M; Koloczek, A; Langer, C; Plag, R; Pohl, M.; Sonnabend, K; Weigand, M; Adachi, T; et al. (Journal of Physics: Conference Series, 2016)
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Impact of tuberculosis treatment length and adherence under different transmission intensities - Pinho, S. T. R.; P. Rodrigues; Andrade, R. F. S.; H. Serra; Lopes, J. S.; Gomes, M. G. M. (THEORETICAL POPULATION BIOLOGY, 2015)
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Subshell resolved inner shell ionization cross-sections of High Z elements by electron impact - Rahangdale, H V; Mitra, D; M Guerra; J P Santos; Saha, S (Journal of Physics: Conference Series, 2015)
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Punching of high strength concrete flat slabs without shear reinforcement - Inácio, Micael M.G.; Almeida, André F.O.; Faria, Duarte M V; Lúcio, Válter J.G.; Ramos, António Pinho (Engineering Structures, 2015)
The experimental research carried out to study the punching behavior of high strength concrete (HSC) flat slabs is reported in the present work. Three flat slab specimens were cast using HSC and another one with normal strength concrete (NSC), to be used as a reference slab. The HSC mix presented a compressive strength of about 130MPa, with a basalt coarse aggregate. The tested specimens were square with 1650mm side and 125mm thickness. The longitudinal reinforcement ratio varied between 0.94{%} and 1.48{%}. The experimental results show that the use of HSC led to a significant load capacity increase when compared with the reference model made with NSC. Furthermore, the experimental results also indicated that as the longitudinal reinforcement ratio increased, the punching capacity also increased. The results obtained in this set of experimental tests and others collected from the literature were compared with the code provisions by EC2, MC2010 and ACI 318-11.
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Keywords: Aggregate size; Flat slabs; High strength concrete; HSC; Punching; Roughness

Down conversion photoluminescence on PVP/Ag-nanoparticles electrospun composite fibers - Baptista AC; Botas AM; Almeida AP; Nicolau AT; Falcão BP; Soares MJ; Leitão JP; Martins R; Borges JP; Ferreira I (Optical Materials, 2015)
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{Performance of timing Resistive Plate Chambers with protons from 200 to 800 MeV} - Machado, J; Adamczewski-Musch, J; Blanco, A; Boretzky, K; Cabanelas, P; Cartegni, L; Marques, R Ferreira; Fonte, P; Fruehauf, J; Galaviz, D; Heil, M; Henriques, A; et al. (Journal of Instrumentation, 2015)
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{TiO2/Cu2O all-oxide heterojunction solar cells produced by spray pyrolysis} - Pavan, Michele; R??hle, Sven; Ginsburg, Adam; Keller, David A.; Barad, Hannah-Noa Noa; Sberna, Paolo M.; Nunes, Daniela; Martins, Rodrigo; Anderson, Assaf Y.; Zaban, Arie; Fortunato, Elvira; Rühle, Sven; et al. (Solar Energy Materials and Solar Cells, 2015)
Here we present for the first time a TiO2/Cu2O all-oxide heterojunction solar cell entirely produced by spray pyrolysis onto fluorine doped tin oxide (FTO) covered glass substrates, using silver as a back contact. A combinatorial approach was chosen to investigate the impact of the TiO2 window layer and the Cu2O light absorber thicknesses. We observe an open circuit voltage up to 350 mV and a short circuit current density which is strongly dependent of the Cu2O thickness, reaching a maximum of {\~{}}0.4 mA/cm2. Optical investigation reveals that a thickness of 300 nm spray pyrolysis deposited Cu2O is sufficient to absorb most photons with an energy above the symmetry allowed optical transition of 2.5 eV, indicating that the low current densities are caused by strong recombination in the absorber that consists of small Cu2O grains.
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Keywords: All-oxide-photovoltaics; High throughput characterization; Spray pyrolysis; TiO2/Cu2O heterojunction

{Performance of timing resistive plate chambers with relativistic neutrons from 300 to 1500 MeV} - Blanco, A; Adamczewski-Musch, J; Boretzky, K; Cabanelas, P; Cartegni, L; Marques, R Ferreira; Fonte, P; Fruehauf, J; Galaviz, D; Heil, M; Henriques, A; Ickert, G; et al. (Journal of Instrumentation, 2015)
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{Imidazole: Prospect Solvent for Lignocellulosic Biomass Fractionation and Delignification} - Morais, Ana Rita C; Pinto, Joana Vaz; Nunes, Daniela; Roseiro, Luísa B; Oliveira, Maria Conceição; Fortunato, Elvira; Bogel-Łukasik, Rafał (ACS Sustainable Chemistry {&} Engineering, 2015)
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Absolute L-shell ionization and X-ray production cross sections of Lead and Thorium by 16-45 keV electron impact - Rahangdale, H V (2015)
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New insights into the lifestyle of \\textitAllosaurus (Dinosauria: Theropoda) based on another specimen with multiple pathologies - Foth,Christian; Evers, Serjoscha W.; Pabst,Ben; Mateus,Octávio; Flisch,Alexander; Patthey,Mike; Rauhut,Oliver W. M. (PeerJ, 2015)
Adult large-bodied theropods are often found with numerous pathologies. A large, almost complete, probably adult \\textitAllosaurus specimen from the Howe Stephens Quarry, Morrison Formation (Late Kimmeridgian–Early Tithonian), Wyoming, exhibits multiple pathologies. Pathologic bones include the left dentary, two cervical vertebrae, one cervical and several dorsal ribs, the left scapula, the left humerus, the right ischium, and two left pedal phalanges. These pathologies can be classified as follows: the fifth cervical vertebra, the scapula, several ribs and the ischium are probably traumatic, and a callus on the shaft of the left pedal phalanx II-2 is probably traumatic-infectious. Traumatically fractured elements exposed to frequent movement (e.g., the scapula and the ribs) show a tendency to develop pseudarthroses instead of a callus. The pathologies in the lower jaw and a reduced extensor tubercle of the left pedal phalanx II-2 are most likely traumatic or developmental in origin. The pathologies on the fourth cervical are most likely developmental in origin or idiopathic, that on the left humerus could be traumatic, developmental, infectious or idiopathic, whereas the left pedal phalanx IV-1 is classified as idiopathic. With exception of the ischium, all as traumatic/traumatic-infectious classified pathologic elements show unambiguous evidences of healing, indicating that the respective pathologies did not cause the death of this individual. Alignment of the scapula and rib pathologies from the left side suggests that all may have been caused by a single traumatic event. The ischial fracture may have been fatal. The occurrence of multiple lesions interpreted as traumatic pathologies again underlines that large-bodied theropods experienced frequent injuries during life, indicating an active predatory lifestyle, and their survival perhaps supports a gregarious behavior for \\textitAllosaurus. Alternatively, the frequent survival of traumatic events could be also related to the presence of non-endothermic metabolic rates that allow survival based on sporadic food consumption or scavenging behavior. Signs of pathologies consistent with infections are scarce and locally restricted, indicating a successful prevention of the spread of pathogens, as it is the case in extant reptiles (including birds).
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Keywords: Archosauria; gregarious behavior; Jurassic; osteomyelitis; paleopathology; pseudarthrosis; Theropoda

Extreme value analysis of the sea levels in Venice - Caeiro,Frederico Almeida Gião Gonçalves; Mateus,Ayana Maria Xavier Furtado; Ramos,Luís Pedro Carneiro (PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF NUMERICAL ANALYSIS AND APPLIED MATHEMATICS 2014, 2015)
The number of floods in the city of Venice has increased substantially in the last decades and can be explained bythe sea level rise and land subsidence. Using Statistics of Extremes we shall model the extreme behaviour of the sea level inVenice and quantify risk through the estimation of important parameters such as return periods of high levels.The number of floods in the city of Venice has increased substantially in the last decades and can be explained bythe sea level rise and land subsidence. Using Statistics of Extremes we shall model the extreme behaviour of the sea level inVenice and quantify risk through the estimation of important parameters such as return periods of high levels.
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Keywords: Extreme quantile; extreme value index; retun level; sea level; Statistics of extremes

Facile and Room-Temperature Activation of Csp3-Cl Bonds by Cheap and Air-Stable Nickel(II) Complexes of (N-Thioether) DPPA-Type Ligands - Ghisolfi, A.; Condello, F.; C. Fliedel; Rosa, V.; Braunstein, P. (Organometallics, 2015)
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Cited By :12Export Date: 17 June 2020

New insights into the lifestyle of Allosaurus (Dinosauria: Theropoda) based on another specimen with multiple pathologies - Foth,Christian; Evers,Serjoscha; Pabst,Ben; Mateus,Octávio; Flisch,Alexander; Patthey,Mike; Rauhut,Oliver W. M. (PeerJ PrePrints, 2015)
Adult large-bodied theropods are often found with numerous pathologies. A large, almost complete, probably adult Allosaurus specimen from the Howe Stephens Quarry, Morrison Formation (Late Kimmeridgian–Early Tithonian), Wyoming, shows multiple pathologies. Pathologic bones include the left dentary, two cervical vertebrae, one cervical and several dorsal ribs, the left scapula, the left humerus, right ischium, and two left pedal phalanges. These pathologies can be classified as follows: the fifth cervical vertebra, the scapula, several ribs and the ischium are traumatic, and a callus on the shaft of the left pedal phalanx II-2 is traumatic-infectious. Traumatically fractured elements exposed to frequent movement (e.g. the scapula and the ribs) show a tendency to develop pseudarthroses instead of callus healing. The pathologies in the lower jaw and a reduced flexor tubercle of the left pedal phalanx II-2 are most likely traumatic or developmental in origin. The pathologies on the fourth cervical are most likely developmental in origin or idiopathic, that on the left humerus is infectious or idiopathic, whereas left pedal phalanx IV-1 is classified as idiopathic. With exception of the ischium, all traumatic / traumatic-infectious pathologic elements show unambiguous evidences of healing, indicating that the respective pathologies did not cause the death of this individual. Alignment of the scapula and rib pathologies from the left side suggests that all may have been caused by a single traumatic event. The ischial fracture may have been fatal. The occurrence of multiple traumatic pathologies again underlines that large-bodied theropods experienced frequent injuries during life, indicating an active predatory lifestyle, and their survival perhaps supports a gregarious behavior for Allosaurus. Signs of infections are scarce and locally restricted, indicating a successful prevention of the spread of pathogens, as it is the case in extant reptiles (including birds).
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Keywords: Archosauria; gregarious behavior; Jurassic; osteomyelitis; paleopathology; pseudarthrosis; Theropoda

P,O-Phosphinophenolate zinc(ii) species: Synthesis, structure and use in the ring-opening polymerization (ROP) of lactide, ε-caprolactone and trimethylene carbonate - C. Fliedel; Rosa, V.; Alves, F.M.; Martins, A.M.; Avilés, T.; S. Dagorne (Dalton Transactions, 2015)
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Cited By :41Export Date: 17 June 2020

Photorheological Ionic Liquids - Avó, João; Cidade, M.T.; Rodriguez, Vincent; Lima, João C; Parola, A Jorge (American Chemical Society, 2015)
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Reactivity of TCNE and TCNQ derivatives of quinonoid zwitterions with Cu(I) - Kauf, T.; Rosa, V.; C. Fliedel; Pattacini, R.; Deibel, N.; Avilés, T.; Sarkar, B.; Braunstein, P. (Dalton Transactions, 2015)
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Cited By :4Export Date: 17 June 2020

Unsymmetrical Chelation of N-Thioether-Functionalized Bis(diphenylphosphino)amine-Type Ligands and Substituent Effects on the Nuclearity of Iron(II) Complexes: Structures, Magnetism, and Bonding - C. Fliedel; Rosa, V.; Falceto, A.; Rosa, P.; Alvarez, S.; Braunstein, P. (Inorganic Chemistry, 2015)
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Cited By :10Export Date: 17 June 2020

An Ornithopod-Dominated Tracksite from the Lower Cretaceous Jiaguan Formation (Barremian–Albian) of Qijiang, South-Central China: New Discoveries, Ichnotaxonomy, Preservation and Palaeoecology - Xing, Lida; Lockley, Martin G.; Marty, Daniel; Zhang, Jianping; Wang, Yan; Klein, Hendrik; McCrea, Richard T.; Buckley, Lisa G.; Belvedere, Matteo; Mateus,Octávio; Gierliński, Gerard D.; Piñuela, Laura; et al. (PLoS ONE, 2015)
The historically-famous Lotus Fortress site, a deep 1.5–3.0-meter-high, 200-meter-long horizonal notch high up in near-vertical sandstone cliffs comprising the Cretaceous Jiaguan Formation, has been known since the 13th Century as an impregnable defensive position. The site is also extraordinary for having multiple tetrapod track-bearing levels, of which the lower two form the floor of part of the notch, and yield very well preserved asseamblages of ornithopod, bird (avian theropod) and pterosaur tracks. Trackway counts indicate that ornithopods dominate (69%) accounting for at least 165 trackmakers, followed by bird (18%), sauropod (10%), and pterosaur (3%). Previous studies designated Lotus Fortress as the type locality of Caririchnium lotus and Wupus agilis both of which are recognized here as valid ichnotaxa. On the basis of multiple parallel trackways both are interpreted as representing the trackways of gregarious species. C. lotus is redescribed here in detail and interpreted to indicate two age cohorts representing subadults that were sometimes bipedal and larger quadrupedal adults. Two other previously described dinosaurian ichnospecies, are here reinterpreted as underprints and considered nomina dubia. Like a growing number of significant tetrapod tracksites in China the Lotus Fortress site reveals new information about the composition of tetrapod faunas from formations in which the skeletal record is sparse. In particular, the site shows the relatively high abundance of Caririchium in a region where saurischian ichnofaunas are often dominant. It is also the only site known to have yielded Wupus agilis. In combination with information from other tracksites from the Jiaguan formation and other Cretaceous formations in the region, the track record is proving increasingly impotant as a major source of information on the vertebrate faunas of the region. The Lotus Fortress site has been developed as a spectacular, geologically-, paleontologically- and a culturally-significant destination within Qijiang National Geological Park.
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Criteria Framework for the Conception of an Adaptive Housing Model for Sub-Saharan Region - Ramalhete, Inês; Amado, P. Miguel; Farias, Hugo (CONFERENCE: HOUSING – A CRITICAL PERSPECTIVE Architecture_MPS, 2015)

Addendum to ‘Revision of the Late Jurassic teleosaurid genus Machimosaurus (Crocodylomorpha, Thalattosuchia)’ - Young, Mark T.; Hua, Stéphane; Steel, Lorna; Foffa, Davide; Stephen L. Brusatte; Thüring, Silvan; Mateus,Octávio; Ruiz-Omeñaca, José Ignacio; Havlik, Philipe; Lepage, Yves; de Andrade, Marco Brandalise (Royal Society Open Science, 2015)
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Aspectos da comunicação matemática na resolução de problemas - M. Botelho; Rocha, H. (Atas do XXVI SIEM, 2015)
The influence of mathematical communication over the students’ learning led to this research, whose main goal is to understand the impact on problem solving of the students’ communication difficulties. The study adopts a qualitative and interpretative methodology, undertaking two case studies of 10th grade students. The reached conclusions point to the students’ difficulties at the interpretation of the problem, namely at the interpretation of figures, and at the interpretation of the available data, especially when part of them is irrelevant to the problem. Some difficulties were also identified at the communication level, in relation to the arguments used by the students to support their ideas, where a clear preference to restrict them to mathematic calculations was identified. Resumo A importância da comunicação matemática sobre a aprendizagem dos alunos, levou à realização desta investigação que pretendeu compreender o impacto sobre a resolução de problemas das dificuldades de comunicação evidenciadas pelos alunos. Optou-se por uma metodologia de natureza qualitativa e interpretativa e pela realização de estudos de caso envolvendo dois alunos do 10.º ano. As conclusões alcançadas apontam para dificuldades na interpretação do enunciado, nomeadamente relativamente às figuras e a dados em quantidade superior ao necessário. Também ao nível da comunicação da resolução foram identificadas dificuldades em fundamentar ideias, evidenciando uma preferência pelo recurso ao cálculo.

Chien augmenté pour l’assistance aux personnes handicapées - Y. Rybarczyk (Colloque International sur la Robotique au Quotidien, 2015)

Comparison of different numerical methods for the solution of the time-fractional reaction-diffusion equation with variable diffusion coefficient - M. L. Morgado; Ferrás, L.; M. Rebelo (15th International Conference on Computational and Mathematical Methods in Science and Engineering (CMMSE 2015), 2015)

A comunicação matemática na avaliação da resolução de problemas - M. Botelho; Rocha, H. (Atas do ProfMat 2015, 2015)
A aprendizagem dos nossos alunos é fortemente influenciada pelas caraterísticas das tarefas que lhes propomos e a resolução de problemas é frequentemente apontada como uma das tarefas com mais potencial para promover aprendizagens ricas. Mas aprender implica ser capaz de desenvolver raciocínios, de comunicar as nossas ideias e de compreender as dos outros num processo argumentativo e reflexivo. A avaliação das aprendizagens num contexto de resolução de problemas envolve assim, necessariamente como parte importante do processo, uma análise da comunicação que se estabelece entre todos os envolvidos. Nesta comunicação iremos focar-nos precisamente na comunicação que se estabelece durante a resolução de problemas, abordando as dificuldades dos alunos e dando atenção à interpretação que fazem do enunciado, à compreensão que manifestam das figuras apresentadas, à relação que conseguem estabelecer entre a situação em causa e a informação disponibilizada através de um gráfico, à forma como conseguem explicitar o seu raciocínio e à linguagem matemática que utilizam no decurso do processo de argumentação. Para tal vamos basear-nos num conjunto de problemas propostos a alunos do 10.º ano de escolaridade no decorrer do estudo de funções.

"Construção Sustentável - conceito e prática" - Amado, P. Miguel; Reaes Pinto, A; Oliveira, Ana M.; Ramalhete, I (Editora Caleidoscópio_Edição e Artes Gráficas, SA, Casal de Cambra, ISBN: 978-989-658-324-8, 2015)

Dos jogos à aprendizagem - C. Moreira; S. Lopes; Rocha, H. (Atas do ProfMat 2015, 2015)
Neste texto apresentamos os jogos no ensino da matemática como uma forma de aprendizagem de conteúdos e não apenas como um recurso que cada professor pode usar nas suas aulas para tornar a aula diferente. Analisamos dois jogos desenvolvidos por nós e que utilizámos com alunos dos 7.º e 10.º anos de escolaridade, procurando não só apresentar os jogos, mas também aspetos da sua implementação em sala de aula, ponderando o contributo que trouxeram à aprendizagem dos alunos. Aprender matemática depende de um grande número de variáveis, o que torna o ensino um processo complexo, pois é necessário que se desenvolva o raciocínio lógico, além de estimular o desenvolvimento das mais variadas capacidades transversais, tais como o pensamento autónomo, a criatividade, o sentido de estratégia e a capacidade de resolver problemas. Duas das dificuldades frequentemente encontradas pelos professores passam pela falta de motivação para a aprendizagem e pelo desinteresse pela Matemática. A solução para estes problemas pode passar pela utilização de jogos para complementar o estudo, mas também para a aquisição de novos conteúdos. No entanto, apenas a implementação dos jogos não basta. O papel do professor é de extrema importância e a planificação e orientação da aula são fundamentais para que se alcancem os objetivos pretendidos.

Dynamic Validation of Contracts in Concurrent Code - Jan Fiedor; Zdenek Letko; João M. Lourenço; Tomas Vojnar (Proceedings of the Fifteenth International Conference on Computer Aided Systems Theory (EUROCAST'15), 2015)
Multi-threaded programs allow one to achieve better performance by doing a lot of work in parallel using multiple threads. Such parallel programs often contain code blocks that a thread must execute atomically, i.e., with no interference from the other threads of the program. Failing to execute these code blocks atomically leads to errors known as atomicity violations. However, frequently it not obvious to tell when a piece of code should be executed atomically, especially when that piece of code contains calls to some third-party library functions, about which the programmer has little or no knowledge at all. One solution to this problem is to associate a contract with such a library, telling the programmer how the library functions should be used, and then check whether the contract is indeed respected. For contract validation, static approaches have been proposed, with known limitations on precision and scalability. In this paper, we propose a dynamic method for contract validation, which is more precise and scalable than static approaches.
(Extended Abstract)

Educative games: the case study of an App to teach handwriting - Y. Rybarczyk (5º Evento Internacional Gestión de Proyectos de Educación Virtual, 2015)

Effect of granular characteristics on the viscoelastic and mechanical properties of native chestnut starch (Castanea sativa Mill) - Lemos, A; Abraão, A.; Cruz, B.; M. L. Morgado; M. Rebelo; Nunes, F.M. (Food Hydrocolloids, 2015)

Flat Slab Punching Behaviour under Cyclic Horizontal Loading - André Almeida, Micael Inácio, Válter Lúcio; António Ramos (fib symposium Copenhagen 2015, Concrete – Innovation and Design, 2015)
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Fractional Pennes’ Bioheat Equation: Theoretical and Numerical Studies - Ferrás, L.; Ford, N.; Nóbrega, J.; M. L. Morgado; M. Rebelo (Fractional Calculus and Applied Analysis, 2015)

Framework Support for the Efficient Implementation of Multi-version Algorithms - Ricardo J. Dias; Vale, Tiago M.; João M. Lourenço (Transactional Memory. Foundations, Algorithms, Tools, and Applications, 2015)
Software Transactional Memory algorithms associate metadata with the memory locations accessed during a transactions lifetime. This metadata may be stored in an external table and accessed by way of a function that maps the address of each memory location with the table entry that keeps its metadata (this is the out-place or external scheme); or alternatively may be stored adjacent to the associated memory cell by wrapping them together (the in-place scheme). In transactional memory multi-version algorithms, several versions of the same memory location may exist. The efficient implementation of these algorithms requires a one-to-one correspondence between each memory location and its list of past versions, which is stored as metadata. In this chapter we address the matter of the efficient implementation of multi-version algorithms in Java by proposing and evaluating a novel in-place metadata scheme for the Deuce framework. This new scheme is based in Java Bytecode transformation techniques and its use requires no changes to the application code. Experimentation indicates that multi-versioning STM algorithms implemented using our new in-place scheme are in average 6 × faster than when implemented with the out-place scheme.
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Keywords: Automatic configuration; Virtual appliance; Virtualization

The graphing calculator in the promotion of mathematical writing - Campos, S.; Viseu, F.; Rocha, H.; Fernandes, J. A. (Proceedings of 12th International Conference onTechnology in Mathematics Teaching, 2015)
Through writing, students express many of their processes and ways of thinking. Since at high school level some of the activities are carried out with the graphing calculator, we intend to investigate the contribution of this resource to promote the mathematical writing in the learning of continuous nonlinear models at 11th grade. Adopting a qualitative methodology, we collected and analyzed the students’ writing productions. What they write when using the calculator gives evidence about the information valued (when they sketch graphics without any justification); about the strategies used (when they define the viewing window and relate different menus on the graphing calculator); and about the reasoning developed (when they justify the information given by the calculator and the formulation of generalizations and conjectures validation).

Identification and comparison of modern and fossil crocodilian eggs and eggshell structures - Marzola, M.; Russo, J.; O. Mateus (Historical Biology, 2015)
Eggshells from the three extant crocodilian species Crocodylus mindorensis (Philippine Crocodile), Paleosuchus palpebrosus (Cuvier's Smooth-fronted Caiman or Musky Caiman) and Alligator mississippiensis (American Alligator or Common Alligator) were prepared for thin section and scanning electron microscope analyses and are described in order to improve the knowledge on crocodilian eggs anatomy and microstructure, and to find new apomorphies that can be used for identification. Both extant and fossil crocodilian eggs present an ornamentation that vary as anastomo-, ramo- or the here newly described rugosocavate type. The angusticaniculate pore system is a shared character for Crocodylomorpha eggshells and some dinosaurian and avian groups. Previously reported signs of incubated crocodilian eggs were found also on our only fertilised and hatched egg. Paleosuchus palpebrosus presents unique organization and morphology of the three eggshell layers, with a relatively thin middle layer characterised by dense and compact tabular microstructure.

The impact of technologies on the teacher's use of different representations - Rocha, H. (Proceedings of 12th International Conference onTechnology in Mathematics Teaching, 2015)
This study intends to characterize how the teacher uses and integrates the different representations provided by the graphing calculator on the process of teaching and learning functions at the secondary level. Specifically, it intends to understand the balance established between the use of the different representations, and the way these representations are articulated. The conclusions reached point to an active use of the graphic and algebraic representations and to a scarce use of the tabular representation. The conclusions also point to a flexible articulation between the two representations usual used, assuming different forms and frequently an interactive approach, repeatedly switching between representations.

The impact of the cultural context on the professional practice of the teacher - Rocha, H. (Proceedings of 8th Annual International Conference of Education, Research and Innovation, 2015)
THE IMPACT OF THE CULTURAL CONTEXT ON THE PROFESSIONAL PRACTICE OF THE TEACHER H. Rocha Universidade NOVA de Lisboa, Faculdade de Ciências e Tecnologia (PORTUGAL) The professional knowledge is a key element of the teacher’s practice. This knowledge is naturally influenced by the teacher’s beliefs and conceptions and by his training, but the context where he develops his practice is perhaps the most decisive influence. At this level, the school where the teacher works and his colleagues are a powerful influence, but the characteristics of his students are even a stronger influence. The cultural diversity of the students and specifically the linguistic diversity are highly relevant elements. A classroom where different languages converge is always a complex context which requires a deeper professional knowledge with inevitable repercussions over the teacher’s practice. This study focuses on a teacher working with a mathematics’ class of foreign students with heavy linguistic limitations on the language of instruction and it intends to analyze the impact of this context on the teacher’s practice. In particular, it intends to analyze how this context interferes with the characteristics of the tasks proposed by the teacher and with the way how mathematical concepts are presented to the students. The study adopts a qualitative and interpretative methodological approach, undertaking one teacher case study. Data were collected during one school year by semi-structured interviews, class observation, and documental data gathering. All interviews and classes observed were audio taped and transcribed. Data analysis was conducted in an interpretative way. The conclusions reached point to an increase on the appreciation of mechanization, to a large reduction in the use of problematic situations and to a presentation of Mathematics as calculation, disconnected from any application, and where reasoning appears as a marginal element or is even missing. The use of several examples becomes a key element of the practice of this teacher. The main finding of this study suggests that language limitations caused a strong impact on the practice of a teacher who considers the understanding and the development of reasoning from the discussion around mathematical ideas as central to the teaching of this subject. It was also possible to identify that the need to find a way to communicate reinforced the formalism of the mathematical language, placing it in the center of the learning process. Keywords: cultural context, teacher’s practice, mathematics.

An implicit finite difference approximation for the solution of the diffusion equation with distributed order in time - Ford, N.; M. L. Morgado; M. Rebelo (Electronic transactions on numerical analysis ETNA, 2015)

Interacción Persona-Maquina: aplicaciones en robótica y juegos digitales - Y. Rybarczyk (Event in the Universidad Tecnológica Indoamérica, 2015)

Knowledge for teaching mathematics with technology and the search for a suitable viewing window to represent functions - Rocha, H. (Proceedings of Cerme 9, 2015)
The usual difficulties of students regarding the choice of an appropriate window when using the graphing calculator in the study of functions and the importance of the teachers’ knowledge to overcoming them, led to this study. The main goal was to characterize the way teachers address the viewing window in the classroom, trying to infer aspects of the Knowledge for Teaching Mathematics with Technology that can justify that practice. The conclusions reached point to the importance of a set of specific knowledge where I highlight the knowledge of the students’ difficulties, the knowledge of mathematical content necessary to understand the impact of the viewing window on the graphic, and the knowledge of teaching strategies that address both the students’ difficulties and the relevant mathematical knowledge.

Mesozoic echinoid diversity in Portugal: Investigating fossil record quality and environmental constraints on a regional scale - Bruno Claro Pereira; Michael J Benton; Marcello Ruta; Mateus,Octávio (Palaeogeography, Palaeoclimatology, Palaeoecology, 2015)
Abstract Several analyses of diversity through geological time use global, synoptic databases, and this practice often makes it difficult to distinguish true signals in changing diversity from regional-scale sampling and/or geological artefacts. Here we investigate how echinoid diversity changed through the Mesozoic of the Lusitanian basin in Portugal based on a comprehensive, revised database, and seek to distinguish biological signal from geological or environmental constraints. The observed diversity pattern is far from having a defined trend, showing many fluctuations that appear to be linked with gaps in the geological record. This study revealed that, independently of the method used, whether correlation tests or model fitting, the diversity signal is not completely explained by the studied sampling proxies. Among the different proxies, marine facies variation in combination with outcrop area best explains the palaeodiversity curve.
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Keywords: Portugal

Múltiplas abordagens, múltiplas representações: um contributo para incrementar a relevância da representação algébrica [Multiple approaches, multiple representations: a contribute to increase the relevance of algebraic representation] - Rocha, H. (Atas do Encontro de Investigação em Educação Matemática, 2015)
A tecnologia e o impacto que esta pode ter sobre as diferentes representações utilizadas e, em particular, sobre a representação algébrica são o foco deste artigo. Procura-se assim compreender como é que o professor enquadra a representação algébrica no trabalho em sala de aula e como a procura tornar relevante para os alunos num contexto de utilização da tecnologia. As conclusões alcançadas apontam para a opção por uma estreita articulação entre as representações algébrica e gráfica e para uma criteriosa escolha de tarefas, envolvendo múltiplas abordagens, onde a representação algébrica vem disponibilizar informação fundamental e tendencialmente inacessível a partir de outras representações.

Numerical approximation of distributed order reaction–diffusion equations - M. L. Morgado; M. Rebelo (Journal of Computational and Applied Mathematics, 2015)

O formal da matemática e o intuitivo da tecnologia: que articulação? - Rocha, H. (Atas do ProfMat 2015, 2015)
A tecnologia é cada vez mais indispensável no dia-a-dia, rodeando-nos constantemente. Para os nossos alunos é uma realidade que conhecem desde sempre e que tendem a encarar com uma naturalidade descontraída e intuitiva. A facilidade de acesso à tecnologia e o modo como esta tende a enfatizar o intuitivo e a relegar para segundo plano o formal e a demonstração matemática são o foco deste artigo. Partindo da análise de uma proposta de trabalho onde alunos de 10.º ano começam por uma abordagem intuitiva apoiada na calculadora gráfica e terminam a realizar uma demonstração da conjectura que formularam, procuro discutir a problemática. As conclusões alcançadas sugerem que é possível colocar aos alunos situações onde estes se podem aperceber da vantagem de recorrer tanto a abordagens mais formais como a abordagens mais intuitivas e isto mesmo quando a tecnologia é uma realidade em sala de aula. Sugere ainda que a realização de demonstrações pode, entre outros aspectos já identificados na literatura, dar um contributo importante para a compreensão de aspectos basilares da Matemática.

O formalismo matemático num contexto de utilização da tecnologia [Mathematical proof in a context of technology integration] - Rocha, H. (Atas do XXVI SIEM, 2015)
The technology and how it tends to emphasize the intuitive and overshadow calculus and mathematical proof are the focus of this paper. The conclusions reached suggest that tasks where students might realize the usefulness of calculus as well as of more intuitive approaches are possible even when the technology is a reality in the classroom. They also suggest that proof may, among other things already identified in the literature, make an important contribution to the students’ understanding of fundamental aspects of mathematics. A tecnologia e a forma como esta tende a enfatizar o intuitivo e a relegar para segundo plano o formal e a demonstração matemática são o foco deste artigo. As conclusões alcançadas sugerem que é possível colocar aos alunos situações onde estes se possam aperceber da vantagem de recorrer tanto a abordagens mais formais como a abordagens mais intuitivas e isto mesmo quando a tecnologia é uma realidade em sala de aula. Sugere ainda que a realização de demonstrações pode, entre outros aspectos já identificados na literatura, dar um contributo importante para a compreensão de aspectos basilares da Matemática.

On the Strong Consistency of Ridge Estimates - Luís Ramos; João Lita da Silva; João Tiago Mexia (Communications in Statistics - Theory and Methods, 2015)

Parametric Elements to Modular Social Housing - Amado, Miguel; Ramalhete, Inês (Architecture_MPS: A JOURNAL OF ARCHITECTURE_MEDIA_POLITICS_SOCIETY, 2015)

Physical vs. Surrogate Models of Passive RF Devices - Passos, Fabio; Kotti, Mouna; Gonzalez-Echevarria, R; Fino, M.H.; Roca, E.; Castro-Lopez, R.; Fernandez, F.V. (2015 IEEE International Symposium on Circuits and Systems, 2015)

Some advances on the Erlang(n) dual risk model - Rodríguez-Martínez, E.V; Cardoso, R. M. R.; Egídio dos Reis, A.D. (ASTIN Bulletin, 2015)

Students' conceptions about the use of graphing calculators on tests - Rocha, H. (Proceedings of 8th Annual International Conference of Education, Research and Innovation, 2015)
STUDENTS’ CONCEPTIONS ABOUT THE USE OF GRAPHING CALCULATORS ON TESTS H. Rocha Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa (PORTUGAL) The assessment is considered a key element of the teaching and learning process and is often divided into two types: formative and summative. The distinction between these two types of assessment is usually made based on the moments in which it occurs and the objectives it has. Nevertheless, there are some continuities between these two types of assessment, and this leads some authors to question whether these two types of assessment should be seen as fully disjoint. Despite this, the prevailing understanding of summative assessment is that it takes place at the end of the learning process and that it is intended to classify the students. The technology and, in particular, the graphing calculator is recognized for the impact it may have on the students’ approaches to solve mathematical questions. When technology is available, several studies point to an higher relevance of the understanding of the mathematical concepts, to an increase in graphical approaches to mathematical questions and to an increment in the use of exploratory approaches to solve the problems that are posed. Of course, all these changes will have its impact also on summative assessment moments, and specifically in testing. Students’ conceptions about the use of technology have a deep impact on how they actually use the technology. The relevance usually attributed to tests, makes it important to understand what determines the performance of students in these moments. This study focuses on the use of the graphing calculator at assessment moments such as tests, intending to understand the students’ conceptions related to that use. Namely it intends to analyze the impact of the students’ conceptions about Mathematics, about the use of technology to learn, and about teachers’ perspectives. The study adopts a qualitative and interpretative methodological approach, undertaking two students’ case studies. Data were collected during one school year by semi-structured interviews, students’ observation at testing moments, and documental data gathering. All interviews were audio recorded and transcribed and the students’ observation was video recorded. Data analysis was conducted in an interpretative way. The conclusions reached suggest that students welcome the possibility of using the graphing calculator during testing. The way this technology allows them to avoid errors, both in the calculations and in the formulas to be used, is the main reason advanced by the students. The speed of resolution, which they consider very important during testing, is another of the valued aspects. The idea of Mathematics as something that you need to understand and where knowing the right formula is not enough to achieve the right answer is pointed as the main justification for the use of this technology in tests. Nevertheless, the idea that technology should not be used seems to be always present. The impact of family ideas and, in particular, the idea that one can become dependent of the graphing calculator, seems to have some influence over the students conceptions about the use of this technology. However, the one that is undoubtedly the decisive reason for this conception is what they consider to be the opinion of a teacher. For the students, a teacher cannot agree with the use of graphing calculators in tests. And the reason given for this is related to the idea that a teacher will not be able to actually understand the students’ mathematical knowledge if he uses the graphing calculator. Keywords: summative assessment, students’ conceptions, technology, mathematics.

"Symmetry-preserving discretization of variational field theories" - Ana Casimiro; César Rodrigo (Arxiv, 2015)

Synthesis and evaluation of new benzimidazole-based COX inhibitors: a naproxen-like interaction detected by STD-NMR - L. C. R. Carvalho; Ribeiro, D; R. S. G. R. Seixas; A. M .S. Silva; M. Nave; A. C. Martins; S. Erhardt; Fernandes, E; Cabrita, E. J.; M. M. B. Marques (RSC Advances, 2015)
Non-steroidal anti-inflammatory drugs exert their pharmacological activity through inhibition of cyclooxygenase 1 and 2 (COX-1 and COX-2). Recent research suggests that a balanced inhibition of both COX-1 and COX-2 is the key to reduce the side-effects exhibited by COX inhibitors. We developed new benzimidazole-based compounds that showed a balanced COX inhibition, supported by molecular docking screening. The human whole blood assays demonstrated that the ester derivatives were potent inhibitors. Competitive saturation transfer difference (STD)-NMR experiments, in the presence of COX-2, using naproxen and diclofenac demonstrated that ester derivatives do not compete with diclofenac for the same binding site, but compete with the allosteric inhibitor naproxen. Combination of NMR spectroscopy with molecular docking has permitted us to detect a new naproxen-like inhibitor, which could be used for future drug development.

Synthesis of cross-linked polymeric microparticles containing hexa-O-benzylsucrose - C.D. Raposo; K. T. Petrova; M. T. Barros (Des. Monomers Polym, 2015)

Towards an augmented assistance dog - Rybarczyk; Y.; Seabra; J.; Vernay; D.; Rybarczyk; P.; Lebret M.C. (3rd World Conference on Information Systems and Technologies, 2015)

Towards the creation of a gesture library - Galveia, Bruno; Cardoso, Tiago; Santor, Vitor; Rybarczyk, Yves (EAI Endorsed Transactions on Creative Technologies, 2015)
The evolution of technology has risen new possibilities in the so called Natural User Interfaces research area. Among distinct initiatives, several researchers are working with the existing sensors towards improving the support to gesture languages. This article tackles the recognition of gestures, using the Kinect sensor, in order to create a gesture library and support the gesture recognition processes afterwards.
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Towards the Design and Implementation of Aspect-Oriented Programming for Spreadsheets - Pedro Maia; Mendes, Jorge; Cunha, Jácome; Henrique Rebêlo; Saraiva, João (Proceedings of the 2nd Workshop on Software Engineering methods in Spreadsheets co-located with the 37th International Conference on Software Engineering (ICSE 2015), 2015)
A spreadsheet usually starts as a simple and single- user software artifact, but, as frequent as in other software systems, quickly evolves into a complex system developed by many actors. Often, different users work on different aspects of the same spreadsheet: while a secretary may be only involved in adding plain data to the spreadsheet, an accountant may define new business rules, while an engineer may need to adapt the spreadsheet content so it can be used by other software systems. Unfortunately, spreadsheet systems do not offer modular mechanisms, and as a consequence, some of the previous tasks may be defined by adding intrusive “code” to the spreadsheet. In this paper we go through the design and implementation of an aspect-oriented language for spreadsheets so that users can work on different aspects of a spreadsheet in a modular way. For example, aspects can be defined in order to introduce new business rules to an existing spreadsheet, or to manipulate the spreadsheet data to be ported to another system. Aspects are defined as aspect-oriented program specifications that are dynamically woven into the underlying spreadsheet by an aspect weaver. In this aspect-oriented style of spreadsheet development, different users develop, or reuse, aspects without adding intrusive code to the original spreadsheet. Such code is added/executed by the spreadsheet weaving mechanism proposed in this paper.

Addendum to ?Revision of the Late Jurassic teleosaurid genus Machimosaurus (Crocodylomorpha, Thalattosuchia)? - Young, M. T.; Hua, S.; Steel, L.; Foffa, D.; Brusatte, S. L.; Thüring, S.; O. Mateus; Ruiz-Omeñaca, J.I.; Havlik, P.; Lepage, Y.; De Andrade, M.B. (Royal Society Open Science, 2015)
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An agent based monitoring architecture for plug and produce based manufacturing systems - Andre Dionisio Rocha; Ricardo Peres; Jose Barata (Industrial Informatics (INDIN), 2015 IEEE 13th International Conference on, 2015)
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Antimicrobial electrospun silver-, copper-and zinc-doped polyvinylpyrrolidone nanofibers - Quirós, Jennifer; Borges, João P; Boltes, Karina; Rodea-Palomares, Ismael; Rosal, Roberto (Journal of hazardous materials, 2015)
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Aromatic aldehydes at the active site of aldehyde oxidoreductase from Desulfovibrio gigas: Reactivity and molecular details of the enzyme-substrate and enzyme-product interaction - Correia, H.D.; Marangon, J.; Brondino, CD; Moura, JJG; Romão, MJ; González, P.J.; Santos-Silva, T (Journal of Biological Inorganic Chemistry, 2015)
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Aromatic aldehydes at the active site of aldehyde oxidoreductase from Desulfovibrio gigas: reactivity and molecular details of the enzyme-substrate and enzyme-product interaction (vol 20, pg 219, 2015) - Correia, Hugo D.; Marangon, Jacopo; Brondino, Carlos D.; Moura, Jose J. G.; Romao, Maria J.; Gonzalez, Pablo J.; Santos-Silva, Teresa (Journal of Biological Inorganic Chemistry, 2015)
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Comparative Failure Analysis of PLA, PLA/GNP and PLA/CNT-COOH Biodegradable Nanocomposites thin Films - V.C. Pinto; Tiago Ramos; Sofia Alves; J. Xavier; Paulo Tavares; P.M.G.P. Moreira; Rui Miranda Guedes (Procedia Engineering, 2015)
Abstract Biodegradable polymers such as poly(lactic) acid (PLA) have been studied for biomaterials applications such as natural human ligament replacement, however these materials could be applied to other sectors as aerospace, aeronautics, automotive, food packaging. \{PLA\} presents a relatively brittle with a mode I fracture behavior, being often blend with other biodegradable or non-degradable polymers to improve its fracture energy. For some existing applications, \{PLA\} components exhibit accumulated permanent deformation resulting from dynamic mechanical inputs, resulting on failure by laxity of parts. Aiming the improvement of \{PLA\} mechanical properties, the inclusion of carbon nanofillers into \{PLA\} matrix, in particular, CNT-COOH and \{GNP\} have been developed, due to their strong sp2 carbon-carbon bondings and their geometric arrangement that enhance mechanical properties of the polymer matrix. \{PLA\} and nanocomposites were produced by melt blending followed by compression molding in a hot press, with small weight percentages of nanofillers added to the matrix. Quasi static tensile tests were performed on a mechanical testing machine (Instron™ ElectroPuls E1000) along with failure analysis of specimens with centered crack with digital image correlation, revealing strain distribution along specimens.
İCSI\} 2015 The 1st International Conference on Structural Integrity Funchal, Madeira, Portugal 1st to 4th September, 2015
Keywords: biodegradable nanocomposites; Biodegradable polymers; CNT-COOH; DIC; FTM; GNP; mechanical failure; PLA

Concentrated photoactivation: focusing light through scattering - Gabriel, A; Machado, J; Gomes, R; Coelho, J. M. P.; Silva, C O; Reis, C P; J P Santos; Vieira, P. (World Congress on Medical Physics and Biomedical Engineering, June 7-12, 2015, Toronto, Canada, 2015)
Light has long being used in medicine; however, the high scattering of biological tissues always hindered its use. The aim of this work is the development of methodologies to focus light inside biological tissues. Geant4/GAMOS Monte Carlo platform was used to simulate the possibility of parameterize the time delay of multiple sources of external light, offset in time, as a function of the interest region position in order to create constructive interferences in a breast sample. A computational model was implemented and the platform was configured in order to perform these simulations. Preliminary results using a single light source were performed. It was concluded that scattering in adipose tissue is very high which is consistent with previous studies.
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A contribution to the rational design of Ru(CO)(3)Cl2L complexes for in vivo delivery of CO - Seixas, Joao D.; Santos, Marino F. A.; Mukhopadhyay, Abhik; Coelho, Ana C.; Reis, Patricia M.; Veiros, Luis F.; Marques, Ana R.; Penacho, Nuno; Goncalves, Ana M. L.; Romao, Maria J.; Bernardes, Goncalo J. L.; Santos-Silva, Teresa; et al. (Dalton Transactions, 2015)
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Design and experimental testing of an adaptive shape-morphing tensegrity structure, with frequency self-tuning capabilities, using shape-memory alloys - Santos, F.A.D.; A. Rodrigues; A Micheletti (Smart Materials and Structures, 2015)
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cited By 25

Effects of forest certification on the ecological condition of Mediterranean streams - Dias, Filipe S.; Bugalho, Miguel N.; Rodríguez-González, Patricia M.; Albuquerque, António; J. Orestes Cerdeira (Journal of Applied Ecology, 2015)
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Keywords: cork oak; forest management; Forest Stewardship Council; freshwater habitats; rapid bio-assessment protocol; riparian vegetation; Stream Visual Assessment Protocol

Eggs and eggshells of Crocodylomorpha from the Upper Jurassic of Portugal - Russo, João Paulo Vasconcelos Mendes (2015)
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Keywords: Crocodiloid; Domínio/Área Científica::Engenharia e Tecnologia::Outras Engenharias e Tecnologias; Eggs and nest; Eggshells; Late Jurassic; Lourinhã Formation; Nesting and reproduction

Erratum: Eu3+ luminescence in aluminophosphate glasses (Journal of Luminescence (2014) 145 (582-587)) - Nico, C.a; Fernandes, R.a; Graça, M.P.F.a; Elisa, M.a; Sava, B.A.b; Monteiro, R.C.C.c; Rino, L.a; Monteiro, T.a (Journal of Luminescence, 2015)
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The homopentameric chlorite dismutase from Magnetospirillum sp. - Freire, D.M.; Rivas, M. G.; Dias, A.M.; Lopes, A. T.; Costa, C; Santos-Silva, T; Van Doorslaer, S.; González, P.J. (Journal of Inorganic Biochemistry, 2015)
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Identification and comparison of modern and fossil crocodilian eggs and eggshell structures - Marzola, M.; Russo, J.; O. Mateus (Historical Biology, 2015)
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Ionic-Liquid-Functionalized Mineral Particles for Protein Crystallization - Kowacz, M.; Marchel, M.; Juknaite, L.; Esperanca, Jmss; Romao, MJ; Carvalho, AL; Rebelo, L. P. N. (Crystal Growth & Design, 2015)
Nucleation is a critical step determining the outcome of the entire crystallization process. Finding an effective nucleant for protein crystallization is of utmost importance for structural biology. The latter relies on good-quality crystals to solve the three-dimensional structures of macromolecules. In this study we show that crystalline barium sulfate (BaSO4) with an etched and/or ionic liquid (IL)-functionalized surface (1) can induce protein nucleation at concentrations well below the concentration needed to promote crystal growth under control conditions, (2) can shorten the nucleation time, (3) can increase the growth rate, and finally (4) may help to improve the protein crystal morphology. These effects were shown for lysozyme, RNase A, trypsin, proteinase K, myoglobin, and hemoglobin. Therefore, the use of BaSO4 particles enables us to reduce the amount of protein in crystallization trials and increases the chance of obtaining protein crystals of the desired quality. In the context of the underlying mechanism, it is shown that the protein-solid contact formation is governed by the interaction of the polar compartments of the biomacromolecule with the support. The tendency of a protein to concentrate near the solid surface is enhanced by both the hydrophobicity of the protein and that of the surface (tuned by the functionalizing IL). These mechanisms of interaction of biomacromolecules with inorganic hydrophilic solids correspond to the principles of amphiphilic IL-mineral interactions.
ISI Document Delivery No.: CK0JB Times Cited: 0 Cited Reference Count: 42 Kowacz, M. Marchel, M. Juknaite, L. Esperanca, J. M. S. S. Romao, M. J. Carvalho, A. L. Rebelo, L. P. N. Esperanca, Jose/B-5116-2008; Esperanca, Jose/0000-0001-9615-8678; Marchel, Mateusz/0000-0002-2274-1139; Juknaite, Lina/0000-0002-5739-7788 Fundacao para a Ciencia e a Tecnologia (FCT), Portugal [PTDC/BBB-BEP/3058/2012, PEst-OE/EQB/LA0004/2013, UID/Multi/04378/2013, PEst-C/EQB/LA0006/2013, RECI/BBB-BEP/0124/2012, SFRH/BPD/63554/2009]; Investigator FCT Program; COMPETE Program The authors thank Dr. Teresa Santos-Silva and Ph.D. student Hugo Correia for kindly providing the crystallization conditions for bovine blood hemoglobin and pancreatic trypsin. The authors acknowledge financial support from Fundacao para a Ciencia e a Tecnologia (FCT), Portugal, through R&D Projects PTDC/BBB-BEP/3058/2012, PEst-OE/EQB/LA0004/2013 (to ITQB), UID/Multi/04378/2013, PEst-C/EQB/LA0006/2013 (to Associate Lab UCIBIO-REQUIMTE), and RECI/BBB-BEP/0124/2012 and also through a postdoctoral grant (SFRH/BPD/63554/2009) and a contract under the Investigator FCT 2012 Program and the COMPETE Program. The authors also thank the ESRF (Grenoble, France) and the Diamond Light Source (Didcot, U.K.) for access to data collection facilities. 9 Amer chemical soc Washington 1528-7505
Keywords: heterogeneous nucleation crystal nucleation adsorption stability surfaces water lysozyme fluorescence polystyrene suspensions Chemistry Crystallography Materials Science

Ligand Binding to Chlorite Dismutase from Magnetospirillum sp. - De Schutter, Amy; Correia, Hugo D.; Freire, Diana M.; Rivas, Maria G; Rizzi, Alberto; Santos-Silva, Teresa; Gonzalez, Pablo J.; Van Doorslaer, Sabine (Journal of Physical Chemistry B, 2015)
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Mesozoic echinoid diversity in Portugal: Investigating fossil record quality and environmental constraints on a regional scale - Pereira, B.C.; Benton, M.J.; Ruta, M.; O. Mateus (Palaeogeography, Palaeoclimatology, Palaeoecology, 2015)
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A multiagent based knowledge extraction framework to support plug and produce capabilities in manufacturing monitoring systems - Rocha, André Dion{\'ısio; Ricardo Silva Peres; Flores, Luis; Jose Barata (Mechatronics and its Applications (ISMA), 2015 10th International Symposium on, 2015)
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One-pot synthesis of dual-stimuli responsive hybrid PNIPAAm-chitosan microgels - Echeverria, Coro; Soares, Paula; Robalo, Ana; Pereira, Laura; Novo, Carlos M. M.; Ferreira, Isabel; João Paulo Borges (Materials & Design, 2015)
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One-step synthesis of ZnO decorated CNT buckypaper composites and their optical and electrical properties - Rodrigues, J.a , Mata, D.a , Pimentel, A.b , Nunes, D.b , Martins, R.b , Fortunato, E.b , Neves, A.J.a , Monteiro, T.a , Costa, (Materials Science and Engineering B: Solid-State Materials for Advanced Technology, 2015)
ZnO/CNT composites were prepared using ZnO nanoparticles and tetrapods synthesized by the Laser Assisted Flow Deposition method. The co-operative behaviour between these two materials may give rise to the production of advanced functional materials with a wide range of applications in electronics and optoelectronics. Despite some degree of aggregation in the case of the nanoparticles, scanning electron microscopy images evidence that the produced ZnO structures are well dispersed in the CNT buckypapers. Independent of the ZnO morphology the samples resistivity was shown to be of the order of ∼10-1 Ω cm while in the case of the electron mobility, the composite with tetrapods reveals a lower value than the ones obtained for the remaining samples. Well-structured ZnO luminescence was observed mainly in ultraviolet highlighting the high optical quality of the produced structures. The temperature dependence of the luminescence reveals a distinct trend for the composites with ZnO tetrapods and ZnO nanoparticles. © 2015 Elsevier B.V.
cited By 3

An ornithopod-dominated tracksite from the lower Cretaceous Jiaguan Formation (Barremian-Albian) of Qijiang, South-Central China: New discoveries, ichnotaxonomy, preservation and palaeoecology - Xing, L.; Lockley, M.G.; Marty, D.; Zhang, J.; Wang, Y.; Klein, H.; McCrea, R.T.; Buckley, L.G.; Belvedere, M.; O. Mateus; Gierli?ski, G.D.; Piñuela, L.; et al. (PLoS ONE, 2015)
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Prediction of the heat gain of external walls: An innovative approach for full-featured excitations based on the simplified method of Mackey-and-Wright - Ruivo, C.R.a b , Vaz, D.C.c d (Applied Energy, 2015)
Nowadays, simulation tools are available for calculating the thermal loads of multiple rooms of buildings, for given inputs. However, due to inaccuracies or uncertainties in some of the input data (e.g., thermal properties, air infiltrations flow rates, building occupancy), the evaluated thermal load may represent no more than just an estimate of the actual thermal load of the spaces. Accordingly, in certain practical situations, simplified methods may offer a more reasonable trade-off between effort and results accuracy than advanced software. Hence, despite the advances in computing power over the last decades, simplified methods for the evaluation of thermal loads are still of great interest nowadays, for both the practicing engineer and the graduating student, since these can be readily implemented or developed in common computational-tools, like a spreadsheet.The method of Mackey and Wright (M&W) is a simplified method that upon values of the decrement factor and time lag of a wall (or roof) estimates the instantaneous rate of heat transfer through its indoor surface. It assumes cyclic behaviour and shows good accuracy when the excitation and response have matching shapes, but it involves non negligible error otherwise, for example, in the case of walls of high thermal inertia.The aim of this study is to develop a simplified procedure that considerably improves the accuracy of the M&W method, particularly for excitations that noticeably depart from the sinusoidal shape, while not introducing a need for an excessive volume of data or complexity in the production of results.In the first simplified procedure discussed in the paper, a full-featured excitation is decomposed into a Fourier series and then the wall's thermal behaviour is reconstructed from the application of the M&W method to each of the N sinusoidal components. Even though this established approach can lead to the most accurate results, given a sufficiently high N, it requires the knowledge of the decrement factor and time lag associated to each component of the Fourier series, which can represent a considerable amount of data.The chief result of the research though is a novel procedure based on a parameter, γ, that weigh-averages the approximate solution obtained by considering a single term Fourier decomposition of the excitation and the solution by considering the actual excitation. The procedure is more accurate than the original M&W method and will be of interest to researchers with the means of generating values of γ for the walls which the end users of their research are interested in. It provides promising results for walls ranging from massive to negligible mass. It has been noticed that while using the same values of γ that had been optimized for the wall facing east, acceptable results are also obtained when altered external excitations are imposed, namely due to intermittency of the direct solar radiation or due to a distinct value of the external heat transfer coefficient. © 2015 Elsevier Ltd.
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Production of poly (vinyl alcohol)(PVA) fibers with encapsulated natural deep eutectic solvent (NADES) using electrospinning - Mano, Francisca; Aroso, Ivo M; Barreiros, Susana; João Paulo Borges; Reis, Rui L; Duarte, Ana Rita C; Paiva, Alexandre (ACS Sustainable Chemistry & Engineering, 2015)
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Proteomic analysis of apoplastic fluid of Coffea arabica leaves highlights novel biomarkers for resistance against Hemileia vastatrix - Guerra-Guimaraes, Leonor; Tenente, Rita; Pinheiro, Carla; Chaves, Ines; Silva, Maria do Ceu; Cardoso, Fernando M. H.; Planchon, Sebastien; Barros, Danielle R.; Renaut, Jenny; Ricardo, Candido P. (Frontiers in Plant Science, 2015)
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Proteomic analysis of apoplastic fluid of Coffea arabica leaves highlights novel biomarkers for resistance against Hemileia vastatrix - Guerra-Guimaraes, Leonor; Tenente, Rita; Pinheiro, Carla; Chaves, Ines; Silva, Maria do Ceu; Cardoso, Fernando M. H.; Planchon, Sebastien; Barros, Danielle R.; Renaut, Jenny; Ricardo, Candido P. (Frontiers in Plant Science, 2015)
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The quest for tolerant varieties: the importance of integrating "omics" techniques to phenotyping - Zivy, Michel; Wienkoop, Stefanie; Renaut, Jenny; Pinheiro, Carla; Goulas, Estelle; Carpentier, Sebastien (Frontiers in Plant Science, 2015)
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Rheo-NMR study of water-based cellulose liquid crystal system at high shear rates - Echeverria, Coro; Almeida, Pedro L; Feio, Gabriel; Figueirinhas, João L; Rey, Alejandro D; Godinho, Maria H (Polymer, 2015)
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Sample Partitioning Estimation for Ergodic Diffusions - Luís P. Ramos; Mota, Pedro; João T. Mexia (Communications in Statistics - Simulation and Computation, 2015)
In this article, we present a new technique to obtain estimators for parameters of ergodic processes. When a diffusion is ergodic its transition density converges to the invariant density Durett (1996). This convergence enabled us to introduce a sample partitioning technique that gives, in each subsample, observations that can be treated as independent and identically distributed. Within this framework, is possible the construction of estimators like maximum likelihood estimators or others.
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Structural insights into xenobiotic and inhibitor binding to human aldehyde oxidase - Coelho, Catarina; Foti, Alessandro; Hartmann, Tobias; Santos-Silva, Teresa; Leimkuehler, Silke; Romao, Maria Joao (Nature Chemical Biology, 2015)
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Structural insights into xenobiotic and inhibitor binding to human aldehyde oxidase - Coelho, C.; Foti, A.; Hartmann, T.; Santos-Silva, T; Leimkühler, S; Romão, MJ (Nature Chemical Biology, 2015)
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A utilização da radiação de sincrotrão no estudo de materiais geológicos; breve abordagem sobre experiências recentes de um grupo de utilizadores - Silva, Teresa Pereira; Veiga, João Pedro; Oliveira, Daniel PS; Batista, Maria João; Rosa, Diogo; Figueiredo, M Ondina (Geonovas, 2015)
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Virtual Testing of the Hygrothermal Residual Stresses in Functionally Graded Composites: Modelling and Optimization. - Silva, Tiago A.N.; Loja, Maria A. R. (IFSA Publishing, 2015)
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{Bioresorbable ureteral stents from natural origin polymers} - Barros, Alexandre A.; Rita, A N A; Duarte, A.R.C.; Pires, Ricardo A.; Sampaio-Marques, Belém; Ludovico, Paula; Lima, Estevão; João F. Mano; Reis, Rui L (Journal of Biomedical Materials Research - Part B Applied Biomaterials, 2015)
In this work, stents were produced from natural origin polysaccharides. Alginate, gellan gum, and a blend of these with gelatin were used to produce hollow tube (stents) following a combination of templated gelation and critical point carbon dioxide drying. Morphological analysis of the surface of the stents was carried out by scanning electron microscopy. Indwelling time, encrustation, and stability of the stents in artificial urine solution was carried out up to 60 days of immersion. In vitro studies carried out with simulated urine demonstrated that the tubes present a high fluid uptake ability, about 1000{%}. Despite this, the materials are able to maintain their shape and do not present an extensive swelling behavior. The bioresorption profile was observed to be highly dependent on the composition of the stent and it can be tuned. Complete dissolution of the materials may occur between 14 and 60 days. Additionally, no encrustation was observed within the tested timeframe. The ability to resist bacterial adherence was evaluated with Gram-positive Staphylococcus aureus and two Gram-negatives Escherichia coli DH5 alpha and Klebsiella oxytoca. For K. oxytoca, no differences were observed in comparison with a commercial stent (Biosoft((R)) duo, Porges), although, for S. aureus all tested compositions had a higher inhibition of bacterial adhesion compared to the commercial stents. In case of E. coli, the addition of gelatin to the formulations reduced the bacterial adhesion in a highly significant manner compared to the commercial stents. The stents produced by the developed technology fulfill the requirements for ureteral stents and will contribute in the development of biocompatible and bioresorbable urinary stents.
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Keywords: aerogel/hydrogel; bioresorbable polymers; kidney stones; natural polymers; supercritical fluid technology; ureteral stents

{Cork processing with supercritical carbon dioxide: Impregnation and sorption studies} - Aroso, Ivo M; Duarte, Ana Rita C; Pires, Ricardo R.; João F. Mano; Reis, Rui L (Journal of Supercritical Fluids, 2015)
Abstract The present study relates to the use of supercritical carbon dioxide (SCCO{<}inf{>}2{<}/inf{>}) to modify the properties of cork by incorporation of new molecules. The impact of SCCO{<}inf{>}2{<}/inf{>}processing on the morphology and on the mechanical properties was found to be negligible.The impregnation of disperse blue 14 (blue dye) on cubic shaped cork samples of 5 mm occurs progressively,is dependent of the processing conditions and of the presence of lenticels and growth rings. The impregnation of the samples bulk was achieved with processing at 10 MPa and 313 K for 16 h. The solubility and sorption of SCCO{<}inf{>}2{<}/inf{>} in the cork matrix was measured using circular discs and the diffusion coefficients calculated to be on the order of 10{<}sup{>}-8{<}/sup{>} cm{<}sup{>}2{<}/sup{>}/s, the same order as for wood materials. This work demonstrates the feasibility of supercritical fluid technology to impart new features to cork, which may lead to innovative architectural, outdoor and industrial applications.
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Keywords: Carbon dioxide; cork; Impregnation; Natural matrices; sorption; Supercritical fluids

{Design of controlled release systems for THEDES - Therapeutic deep eutectic solvents, using supercritical fluid technology} - Aroso, I.M.; Craveiro, R.; Rocha, Â.; M. Dionísio; S. Barreiros; Reis, R.L.; Paiva, A.; Duarte, A.R.C. (International Journal of Pharmaceutics, 2015)
© 2015 Elsevier B.V. Abstract Deep eutectic solvents (DES) can be formed by bioactive compounds or pharmaceutical ingredients. A therapeutic DES (THEDES) based on ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), and menthol was synthesized and its thermal behavior was analyzed by differential scanning calorimetry (DSC). A controlled drug delivery system was developed by impregnating a starch:poly-Ï$μ$-caprolactone polymeric blend (SPCL 30:70) with the menthol:ibuprofen THEDES in different ratios (10 and 20 wt{%}), after supercritical fluid sintering at 20 MPa and 50 °C. The morphological characterization of SPCL matrices impregnated with THEDES was performed by scanning electron microscopy (SEM) and micro-computed tomography (micro-CT). Drug release studies were carried out in a phosphate buffered saline. The results obtained provide important clues for the development of carriers for the sustainable delivery of bioactive compounds.
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Keywords: Biodegradable polymers; Drug delivery systems; Ibuprofen; supercritical carbon dioxide; Therapeutic deep eutectic solvents

{Ketoprofen-eluting biodegradable ureteral stents by CO{<}inf{>}2{<}/inf{>}impregnation: In vitro study} - Barros, A.A.; Oliveira, C.; Reis, R.L.; Lima, E.; Duarte, A.R.C. (International Journal of Pharmaceutics, 2015)
© 2015 Elsevier B.V. Ureteral stents are indispensable tools in urologic practice. The main complications associated with ureteral stents are dislocation, infection, pain and encrustation. Biodegradable ureteral stents are one of the most attractive designs with the potential to eliminate several complications associated with the stenting procedure. In this work we hypothesize the impregnation of ketoprofen, by CO 2 -impregnation in a patented biodegradable ureteral stent previously developed in our group. The biodegradable ureteral stents with each formulation: alginate-based, gellan gum-based were impregnated with ketoprofen and the impregnation conditions tested were 100 bar, 2 h and three different temperatures (35 °C, 40°C and 50°C). The impregnation was confirmed by FTIR and DSC demonstrated the amorphization of the drug upon impregnation. The in vitro elution profile in artificial urine solution (AUS) during degradation of a biodegradable ureteral stent loaded with ketoprofen was evaluated. According to the kinetics results these systems have shown to be very promising for the release ketoprofen in the first 72 h, which is the necessary time for anti-inflammatory delivery after the surgical procedure. The in vitro release studied revealed an influence of the temperature on the impregnation yield, with a higher impregnation yield at 40°C. Higher yields were also obtained for gellan gum-based stents. The non-cytotoxicity characteristic of the developed ketoprofen-eluting biodegradable ureteral stents was evaluated in L929 cell line by MTS assay which demonstrated the feasibility of this product as a medical device.
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Keywords: Biodegradable polymers; Hydrogel; Ketoprofen-eluting; kidney stones; natural polymers; supercritical fluid technology; ureteral stents

{Novel non-cytotoxic alginate–lignin hybrid aerogels as scaffolds for tissue engineering} - Quraishi, Sakeena; Martins, Marta; Barros, Alexandre A.; Gurikov, Pavel; Raman, S. P.; Smirnova, Irina; Duarte, Ana Rita C; Reis, Rui L (Journal of Supercritical Fluids, 2015)
This paper presents a novel approach toward the production of hybrid alginate–lignin aerogels. The key idea of the approach is to employ pressurized carbon dioxide for gelation. Exposure of alginate and lignin aqueous alkali solution containing calcium carbonate to CO2at 4.5 MPa resulted in a hydrogel formation. Various lignin and CaCO3concentrations were studied. Stable hydrogels could be formed up to 2:1 (w/w) alginate-to-lignin ratio (1.5 wt{%} overall biopolymer concentration). Upon substitution of water with ethanol, gels were dried in supercritical CO2to produce aerogels. Aerogels with bulk density in the range 0.03–0.07 g/cm3, surface area up to 564 m2/g and pore volume up to 7.2 cm3/g were obtained. To introduce macroporosity, the CO2induced gelation was supplemented with rapid depressurization (foaming process). Macroporosity up to 31.3 ± 1.9{%} with interconnectivity up to 33.2 ± 8.3{%} could be achieved at depressurization rate of 3 MPa/min as assessed by micro-CT. Young's modulus of alginate–lignin aerogels was measured in both dry and wet states. Cell studies revealed that alginate–lignin aerogels are non-cytotoxic and feature good cell adhesion making them attractive candidates for a wide range of applications including tissue engineering and regenerative medicine.
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Keywords: Alginate; biomaterials; Lignin; Scaffolds; Supercritical; tissue engineering

{Preparation of macroporous alginate-based aerogels for biomedical applications} - Martins, Marta; Barros, Alexandre A.; Quraishi, Sakeena; Gurikov, Pavel; Raman, S. P.; Smirnova, Irina; Duarte, Ana Rita C; Reis, Rui L (Journal of Supercritical Fluids, 2015)
Aerogels are a special class of ultra-light porous materials with growing interest in biomedical applications due to their open pore structure and high surface area. However, they usually lack macroporosity, while mesoporosity is typically high. In this work, carbon dioxide induced gelation followed by expansion of the dissolved CO{<}inf{>}2{<}/inf{>} was performed to produce hybrid calcium-crosslinked alginate-starch hydrogels with dual meso- and macroporosity. The hydrogels were subjected to solvent exchange and supercritical drying to obtain aerogels. Significant increase in macroporosity from 2 to 25{%} was achieved by increasing expansion rate from 0.1 to 30 bar/min with retaining mesoporosity (BET surface and BJH pore volume in the range 183-544m{<}sup{>}2{<}/sup{>}/g and 2.0-6.8cm{<}sup{>}3{<}/sup{>}/g, respectively). In vitro bioactivity studies showed that the alginate-starch aerogels are bioactive, i.e. they form hydroxyapatite crystals when immersed in a simulated body fluid solution. Bioactivity is attributed to the presence of calcium in the matrix. The assessment of the biological performance showed that the aerogels do not present a cytotoxic effect and the cells are able to colonize and grow on their surface. Results presented in this work provide a good indication of the potential of the alginate-starch aerogels in biomedical applications, particularly for bone regeneration.
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Keywords: Aerogels; Alginate; CO{<}inf{>}2{<}/inf{>} induced gelation; starch; Supercritical fluids; tissue engineering

{Water and carbon dioxide: Green solvents for the extraction of collagen/gelatin from marine sponges} - Barros, Alexandre A.; Aroso, Ivo M; Silva, Tiago H.; João F. Mano; Duarte, Ana Rita C; Reis, Rui L (ACS Sustainable Chemistry and Engineering, 2015)
Marine sponges are extremely rich in natural products and are considered a promising biological resource. The major objective of this work is to couple a green extraction process with a natural origin raw material to obtain sponge origin collagen/gelatin for biomedical applications. Marine sponge collagen has unique physicochemical properties, but its application is hindered by the lack of availability due to inefficient extraction methodologies. Traditional extraction methods are time consuming as they involve several operating steps and large amounts of solvents. In this work, we propose a new extraction methodology under mild operating conditions in which water is acidified with carbon dioxide (CO2) to promote the extraction of collagen/gelatin from different marine sponge species. An extraction yield of approximately 50{%} of collagen/gelatin was achieved. The results of Fourier transformed infrared spectroscopy (FTIR), circular dichroism (CD), and differential scanning calorimetry (DSC) spectra suggest a mixture of collagen/gelatin with high purity, and the analysis of the amino acid composition has shown similarities with collagen from other marine sources. Additionally, in vitro cytotoxicity studies did not demonstrate any toxicity effects for three of the extracts.
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Keywords: Carbon dioxide; Collagen; Extraction; gelatin; Green solvents; Marine sponges; Natural products; water

{Copper(II) complexes of bis(aryl-imino)acenaphthene ligands: synthesis, structure, DFT studies and evaluation in reverse ATRP of styrene} - Fliedel, Christophe; Vitor Rosa,; Santos, Carla I. M.; Gonzalez, Pablo J.; Almeida, Rui M.; Gomes, Clara S. B.; Gomes, Pedro T.; Lemos, M. Amelia N. D. A.; Aullon, Gabriel; Richard Welter,; Aviles, Teresa (DALTON TRANSACTIONS, 2014)
{Two new Ar-BIAN Cu(II) complexes (where Ar-BIAN = bis(aryl-imino)acenaphthene) of formulations {[}CuCl2(Mes-BIAN)] (1) (Mes = 2,4,6-Me3C6H2) and {[}CuCl2(Dipp-BIAN)] (2) (Dipp = 2,6-iPr(2)C(6)H(3)) were synthesised by direct reaction of CuCl2 suspended in dichloromethane with the respective ligands Mes-BIAN (L1) and Dipp-BIAN (L2), dissolved in dichloromethane, under an argon atmosphere. Attempts to obtain these compounds by solubilising CuCl2 in methanol and adding a dichloromethane solution of the corresponding ligand, under aerobic conditions, gave also compound 1, but, in the case of L2, the Cu(I) dimer {[}CuCl(Dipp-BIAN)](2) (3) was obtained instead of compound 2. The compounds were fully characterised by elemental analyses, MALDI-TOF mass spectrometry, FT-IR, H-1 NMR and EPR spectroscopic techniques. The solid-state molecular structures of compounds 1-3 were determined by single crystal X-ray diffraction, showing the expected chelation of the Ar-BIAN ligands and two chloride ligands completing the coordination sphere of the Cu(11) centre. In the case of the complex 1, an intermediate coordination geometry around the Cu(II) centre, between square planar and tetrahedral, was revealed, while the complex 2 showed an almost square planar geometry. The structural differences and evaluation of energetic changes were rationalised by DFT calculations. Analysis of the electrochemical behaviour of complexes 1-3 was performed by cyclic voltammetry and the experimental redox potentials for Cu(II)/Cu(I) pairs have been compared with theoretical values calculated by DFT in the gas phase and in dichloromethane and methanol solutions. The complex 1 exhibited good activity in the reverse atom transfer radical polymerisation (ATRP) of styrene.}
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Cost-Effectiveness Analysis of Optimal Control Measures for Tuberculosis - Rodrigues, Paula; Silva, Cristiana J.; Torres, Delfim F. M. (BULLETIN OF MATHEMATICAL BIOLOGY, 2014)
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Interpreting measures of tuberculosis transmission: a case study on the Portuguese population - Lopes, Joao Sollari; Rodrigues, Paula; Pinho, Suani T. R.; Andrade, Roberto F. S.; Duarte, Raquel; Gomes, M. Gabriela M. (BMC INFECTIOUS DISEASES, 2014)
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{One Electron Reduced Square Planar Bis(benzene-1,2-dithiolato) Copper Dianionic Complex and Redox Switch by O-2/HO-} - Maiti, Biplab K.; Maia, Luisa B.; Pal, Kuntal; Pakhira, Bholanath; Aviles, Teresa; Moura, Isabel; Pauleta, Sofia R; Nunez, Jose L.; Rizzi, Alberto C.; Brondino, Carlos D.; Sarkar, Sabyasachi; Moura, Jose J. G. (INORGANIC CHEMISTRY, 2014)
{The complex {[}Ph4P](2){[}Cu(bdt)(2)] (1(red)) was synthesized by the reaction of {[}Ph4P]2{[}S2MoS2CuCl] with H2bdt (bdt = benzene-1,2-dithiolate) in basic medium. 1(red) is highly susceptible toward dioxygen, affording the one electron oxidized diamagnetic compound {[}Ph4P]{[}Cu(bdt)(2)] (1(ox)). The interconversion between these two oxidation states can be switched by addition of O-2 or base (Et4NOH = tetraethylammonium hydroxide), as demonstrated by cyclic voltammetry and UV-visible and EPR spectroscopies. Thiomolybdates, in free or complex forms with copper ions, play an important role in the stability of 1(red) during its synthesis, since in its absence, 1(ox) is isolated. Both 1(red) and 1(ox) were structurally characterized by X-ray crystallography. EPR experiments showed that 1(red) is a Cu(II)-sulfur complex and revealed strong covalency on the copper-sulfur bonds. DFT calculations confirmed the spin density delocalization over the four sulfur atoms (76%) and copper (24%) atom, suggesting that 1(red) has a ``thiyl radical character{''}. Time dependent DFT calculations identified such ligand to ligand charge transfer transitions. Accordingly, 1(red) is better described by the two isoelectronic structures {[}Cu(I)(bdt(2), 4S(3-{*}))](2-) {[}Cu-II(bdt(2), 4S(4-))](2-). On thermodynamic grounds, oxidation of 1(red) (doublet state) leads to 1(ox) singlet state, {[}Cu-III(bd(t)2, 4S(4-))](1-).}
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Comparison of modern and fossil Crocodylomorpha eggs and contribution to the oophylogeny of Amniota - Marzola, M.; O. Mateus; Russo, J.; Milàn, J. (XII Annual Meeting of the European Association of Vertebrate Palaeontologists, 2014)
Alternative reference format: Marzola M., Mateus O, Russo J., & Milàn J. 2014. . p. 109. In: Delfino M., Carnevale G., & Pavia M. (Eds.). Abstract Book and Field Trip Guide, XII Annual Meeting of the European Association of Vertebrate Palaeontologists. Museo Regionale di Scienze Naturali, Regione Piemonte, Torino, pp. 192

Determination of subshell-resolved L-shell-ionization cross sections of gold induced by 15–40-keV electrons - Rahangdale, H V; M Guerra; Das, P K; De, S.; J P Santos; Mitra, D; Saha, S (Physical Review A, 2014)
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INSIGHTS INTO THE CATALYTICCYCLE OF Pseudomonas nautica NITROUS OXIDE REDUCTASE - Moura, I; Carreira, C.; Pauleta, S.; Nunes, R. F.; Moura, J J; Ramos, S.; Dell'acqua, S.; Einsle, O. (Journal of Biological Inorganic Chemistry, 2014)
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Suppl. 1Ac9du1711116Times Cited:0Cited References Count:5

Determination of subshell-resolved L-shell-ionization cross sections of gold induced by 15–40-keV electrons - Rahangdale, H V; M Guerra; Das, P K; De, S.; J P Santos; Mitra, D; Saha, S (Physical Review A, 2014)
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{$^{13,14}$B(n, $γ$) via Coulomb Dissociation for Nucleosynthesis towards the r-Process} - Altstadt, S G; Adachi, T; Aksyutina, Y; Alcantara, J; Alvarez-Pol, H; Ashwood, N; Atar, L; Aumann, T; Avdeichikov, V.; Barr, M; Beceiro, S; Bemmerer, D.; et al. (Nuclear Data Sheets, 2014)
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Determination of the active form of the tetranuclear copper sulfur cluster in nitrous oxide reductase - Johnston, E. M.; Dell'acqua, S.; Ramos, S.; Pauleta, S. R.; Moura, I; Solomon, E. I. (J Am Chem Soc, 2014)
N2OR has been found to have two structural forms of its tetranuclear copper active site, the 4CuS Cu(Z)* form and the 4Cu2S Cu(Z) form. EPR, resonance Raman, and MCD spectroscopies have been used to determine the redox states of these sites under different reductant conditions, showing that the Cu(Z)* site accesses the 1-hole and fully reduced redox states, while the Cu(Z) site accesses the 2-hole and 1-hole redox states. Single-turnover reactions of N2OR for Cu(Z) and Cu(Z)* poised in these redox states and steady-state turnover assays with different proportions of Cu(Z) and Cu(Z)* show that only fully reduced Cu(Z)* is catalytically competent in rapid turnover with N2O.
Johnston, Esther MDell'Acqua, SimoneRamos, SusanaPauleta, Sofia RMoura, IsabelSolomon, Edward IR01 DK031450/DK/NIDDK NIH HHS/United StatesR37 DK031450/DK/NIDDK NIH HHS/United StatesDK-31450/DK/NIDDK NIH HHS/United StatesResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tUnited StatesJournal of the American Chemical SocietyJ Am Chem Soc. 2014 Jan 15;136(2):614-7. doi: 10.1021/ja411500p. Epub 2014 Jan 7.
Keywords: Copper/chemistry/*metabolism; Marinobacter/*enzymology; Models, Molecular; Oxidoreductases/chemistry/*metabolism; Sulfur/chemistry/*metabolism

A Dynamic Agent-Based Modeling Framework for Digital Business Models: Applications to Facebook and a Popular Portuguese Online Classifieds Website - Zutshi Aneesh; Grilo António; Jardim-Gonçalves Ricardo (2014)
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DYNAMOD—An Agent Based Modeling Framework: Applications to Online Social Networks - Zutshi Aneesh; Grilo Antonio; Jardim-Gonçalves Ricardo (2014)
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Framework for Customers’ Sentiment Analysis - Marques-Lucena Catarina; Sarraipa João; Fonseca Joaquim; Grilo António; Jardim-Gonçalves Ricardo (2014)
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A semi-parametric estimator of a shape second order parameter. - Caeiro, F.; Gomes, M. I: (New Advances in Statistical Modeling and Applications, 2014)
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Simulating digital businesses using an agent based modeling approach - Zutshi A; Grilo A; Jardim-Gonçalves R (2014)
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A synthesis of copper based metal-organic framework for O-acetylation of alcohols - Singh Savita; Kale Sandip; Gawande Manoj; Velhinho Alexandre; Jayarama Radha (2014)
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{Visible-Light Photocatalysis in Ca0.6Ho0.4MnO3 Films Deposited by RF-Magnetron Sputtering Using Nanosized Powder Compacted Target} - Barrocas, B.; Sério, S.; Rovisco, A.; Melo Jorge, M. E. (The Journal of Physical Chemistry C, 2014)
A novel immobilized Ca0.6Ho0.4MnO3 photocatalyst has been developed with high photocatalytic activity for Rhodamine 6G (Rh6G) photodegradation under visible light irradiation. The nanocrystalline Ca0.6Ho0.4MnO3 films were successfully deposited by RF-magnetron sputtering on unheated quartz glass substrates using Ca0.6Ho0.4MnO3 powder as sputtering target and its photocatalytic functionalities have been explored. The visible-light-responsive photocatalytic activity of Ca0.6Ho0.4MnO3 films was evaluated by the photodegradation of Rh6G aqueous solutions under visible light irradiation. The reusability of Ca0.6Ho0.4MnO3 films on fresh dye samples was studied, showing an efficient reuse, without decreasing the photocatalytic decolorization efficiency. Furthermore, X-ray diffraction of the reused films did not reveal additional phases indicating high photochemical stability of the films even after reusing them in successive runs. The photocatalytic efficiency of the nanocrystalline Ca0.6Ho0.4MnO3 films was further compared with TiO2 films also produced by sputtering and the results revealed a significant improvement in photocatalytic activity over TiO2 under visible light irradiation. Almost complete photodecolorization of a 5 ppm Rh6G solution was achieved in 4 h, while only 64% of dye degradation was observed in TiO2 photoassisted process. This work provides a feasible route to fabricate high-performance immobilized ABO3-based nanomaterials, and the finding opens up a new venue for designing visible light sensitive ternary compounds for photocatalytical applications. A novel immobilized Ca0.6Ho0.4MnO3 photocatalyst has been developed with high photocatalytic activity for Rhodamine 6G (Rh6G) photodegradation under visible light irradiation. The nanocrystalline Ca0.6Ho0.4MnO3 films were successfully deposited by RF-magnetron sputtering on unheated quartz glass substrates using Ca0.6Ho0.4MnO3 powder as sputtering target and its photocatalytic functionalities have been explored. The visible-light-responsive photocatalytic activity of Ca0.6Ho0.4MnO3 films was evaluated by the photodegradation of Rh6G aqueous solutions under visible light irradiation. The reusability of Ca0.6Ho0.4MnO3 films on fresh dye samples was studied, showing an efficient reuse, without decreasing the photocatalytic decolorization efficiency. Furthermore, X-ray diffraction of the reused films did not reveal additional phases indicating high photochemical stability of the films even after reusing them in successive runs. The photocatalytic efficiency of the nanocrystalline Ca0.6Ho0.4MnO3 films was further compared with TiO2 films also produced by sputtering and the results revealed a significant improvement in photocatalytic activity over TiO2 under visible light irradiation. Almost complete photodecolorization of a 5 ppm Rh6G solution was achieved in 4 h, while only 64% of dye degradation was observed in TiO2 photoassisted process. This work provides a feasible route to fabricate high-performance immobilized ABO3-based nanomaterials, and the finding opens up a new venue for designing visible light sensitive ternary compounds for photocatalytical applications.
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One electron reduced square planar bis(benzene-1,2-dithiolato) copper dianionic complex and redox switch by O2/HO(-) - Maiti, B. K.; Maia, L. B.; Pal, K.; Pakhira, B.; Aviles, T.; Moura, I; Pauleta, S. R.; Nunez, J. L.; Rizzi, A. C.; Brondino, CD; Sarkar, S.; Moura, J J (Inorg Chem, 2014)
The complex [Ph4P]2[Cu(bdt)2] (1(red)) was synthesized by the reaction of [Ph4P]2[S2MoS2CuCl] with H2bdt (bdt = benzene-1,2-dithiolate) in basic medium. 1(red) is highly susceptible toward dioxygen, affording the one electron oxidized diamagnetic compound [Ph4P][Cu(bdt)2] (1(ox)). The interconversion between these two oxidation states can be switched by addition of O2 or base (Et4NOH = tetraethylammonium hydroxide), as demonstrated by cyclic voltammetry and UV-visible and EPR spectroscopies. Thiomolybdates, in free or complex forms with copper ions, play an important role in the stability of 1(red) during its synthesis, since in its absence, 1(ox) is isolated. Both 1(red) and 1(ox) were structurally characterized by X-ray crystallography. EPR experiments showed that 1(red) is a Cu(II)-sulfur complex and revealed strong covalency on the copper-sulfur bonds. DFT calculations confirmed the spin density delocalization over the four sulfur atoms (76%) and copper (24%) atom, suggesting that 1(red) has a "thiyl radical character". Time dependent DFT calculations identified such ligand to ligand charge transfer transitions. Accordingly, 1(red) is better described by the two isoelectronic structures [Cu(I)(bdt2, 4S(3-,)*)](2-) <--> [Cu(II)(bdt2, 4S(4-))](2-). On thermodynamic grounds, oxidation of 1(red) (doublet state) leads to 1(ox) singlet state, [Cu(III)(bdt2, 4S(4-))](1-).
Maiti, Biplab KMaia, Luisa BPal, KuntalPakhira, BholanathAviles, TeresaMoura, IsabelPauleta, Sofia RNunez, Jose LRizzi, Alberto CBrondino, Carlos DSarkar, SabyasachiMoura, Jose J GUnited StatesInorganic chemistryInorg Chem. 2014 Dec 15;53(24):12799-808. doi: 10.1021/ic501742j. Epub 2014 Dec 3.

Experimental and FE updating techniques for the unseating vulnerability assessment of a footbridge structure - Corneliu Cismasiu; Filipe P. Amarante dos Santos; Ana I.M. Rodrigues (The 4th International Conference on Dynamics, Vibration and Control, 2014)

{Characterization and electrochemical behaviour of nanostructured calcium samarium manganite electrodes fabricated by RF-Magnetron Sputtering} - Barrocas, B.; Sério, S.; Rovisco, A.; Y. Nunes; de Sá, A.I.; Pereira, M.I. da Silva; Jorge, M.E. Melo (Electrochimica Acta, 2014)
Ca1-xSmxMnO3 (0≤x≤0.4) films were successfully fabricated on Indium Tin Oxide (ITO) coated quartz glass substrates by radio frequency magnetron sputtering technique (RF- magnetron sputtering) from compacted nanosized powder targets, and subsequent annealing at 800°C in air, for 6h. X-ray diffraction shows a pure typical perovskite phase for x≥0.1. Scanning electron microscopy and atomic force microscopy revealed that the film surface is dense, with low roughness, depending on the Sm content, even though a few cracks were observed. Crystallite size was found to decrease with the Sm content. The electrodes were characterized by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS).The oxide electrode's capacitance was estimated using both techniques and the corresponding roughness factors evaluated. The values obtained from the two methods show a good agreement. A comparison between the voltammetric data and those referred in the literature allowed finding out that the redox reaction occurring at the electrode surface involves the pair Mn4+/Mn3+. EIS measurements confirm the voltammetric data and they also give additional information about the film porosity and the charge transfer resistance. This last parameter is associated with the oxidation and reduction of the pair Mn3+/Mn4+and after normalized by the roughness factor shows an increase with samarium content.
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Keywords: Ca1-xSmxMnO3 films; Cyclic voltammetry; Electrochemical impedance spectroscopy; Electrode roughness; Manganites electrodes; RF-magnetron sputtering

Eco-wall modular solutions for buildings - Amado, M. P.; Pinho, F.; Faria, P.; Ramalhete, I (9th International Masonry Conference, 2014)

A Cascode-Free Single-Stage Amplifier Using a Fully-Differential Folded Voltage-Combiner - Póvoa R.; Lourenço N.; Horta N.; Goes J. (21st IEEE International Conference on Electronics Circuits and Systems, 2014)

Eco-wall modular solutions for buildings - Amado, Miguel; Fernando Pinho; Faria, Paulina; Ramalhete, Inês (IMC2014 - 9th International Masonry Conference 2014, 2014)

Combined experimental and theoretical study of bis(diphenylphosphino)(N -thioether)amine-type ligands in nickel(II) complexes for catalytic ethylene oligomerization - Ghisolfi, A.; C. Fliedel; Rosa, V.; Monakhov, K.Y.; Braunstein, P. (Organometallics, 2014)
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Cited By :28Export Date: 17 June 2020

Copper(ii) complexes of bis(aryl-imino)acenaphthene ligands: Synthesis, structure, DFT studies and evaluation in reverse ATRP of styrene - C. Fliedel; Rosa, V.; Santos, C. I. M.; Gonzalez, P. J.; Almeida, R. M.; Gomes, C.S.B.; Gomes, P. T.; Lemos, M.A.N.D.A.; Aullón, G.; Welter, R.; Avilés, T. (Dalton Transactions, 2014)
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Cited By :12Export Date: 17 June 2020

Experimental and FE updating techniques for the unseating vulnerability assessment of a footbridge structure. - Corneliu Cismasiu; Amarante dos Santos, Filipe; Ana Rodrigues (The 4th International Conference on Dynamics, Vibration and Control, 2014)

Janus microspheres for visual assessment of molecular interconnects - C. Fliedel; Faramarzi, V.; Rosa, V.; Doudin, B.; Braunstein, P. (Chemistry - A European Journal, 2014)
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Cited By :12Export Date: 17 June 2020

Polyurea dendrimer for efficient cytosolic siRNA delivery - Restani, Rita B.; Conde, Joao; Baptista, Pedro V.; Cidade, Maria Teresa; Bragança, Ana M; Morgado, Jorge; Correia, Ilídio J.; Aguiar-Ricardo, Ana; Bonifácio, Vasco D. B. (Royal Society of Chemistry, 2014)
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Probing the influence of the ligands on the magnetism of dinuclear manganese, iron, and chromium complexes supported by aroylhydrazone - Domingo, A.; Specklin, D.; Rosa, V.; Mameri, S.; Robert, V.; Welter, R. (European Journal of Inorganic Chemistry, 2014)
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Cited By :5Export Date: 17 June 2020

PVA composite catalytic membranes for hyacinth flavour synthesis in a pervaporation membrane reactor - Ceia, T. F.; Silva, A G; Ribeiro, C S; Pinto, JV; Casimiro, MH; Ramos, A. M.; Vital, J (Catalysis Today, 2014)
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Contribution of the social sciences in the transformation of informal communities - Neves, S. O.; P. Rodrigues; Amado, M. P. (40th IAHS World Congress in Housing – Sustainable Housing Construction. 21 - ISBN: 978-989-98949-0-7, 2014)

Low Cost Adaptive Housing Model - Ramalhete, I; Amado, M. P.; Farias, H. (40th IAHS World Congress in Housing – Sustainable Housing Construction.54, ISBN: 978-989-98949-0-7, 2014)

A numerical method for the solution of the time-fractional diffusion equation - Ferrás, L.; Ford, N.; Morgado, L.; M. Rebelo (Computational Science and Its Applications – ICCSA 2014, 2014)

. Kinect-Sign: teaching sign language to listeners through a game - Gameiro; J.; Cardoso; T.; Rybarczyk Y. (Innovative and Creative Developments in Multimodal Interaction Systems, 2014)

5. Inhibition of LOX by Flavonoids: a Structure Activity Relationship Study - Ribeiro D., Freitas M., Tomé S. M., Silva Artur M. S., Porto G., Cabrita E. J., Marques M. M. B., Fernandes E. (Eur. J. Med. Chem., 2014)

Análise Numérica Não Linear do Punçoamento em Lajes Fungiformes – Calibração - Mamede, Nuno; Faria, Duarte; António Ramos (Revista Internacional Tech ITT, 2014)

Análise Numérica Não Linear do Punçoamento em Lajes Fungiformes – Estudo Paramétrico - Mamede, Nuno; Faria, Duarte; António Ramos (Revista Internacional Tech ITT, 2014)

Analog-to-Digital Converters with embedded IF mixing using variable reference voltages - Pereira N.; Goes J.; Oliveira L. B.; Dinis R. (IEEE International Symposium on Circuits and Systems (ISCAS), 2014)

Assessing and improving management practices when planning packaging waste collection systems - Tânia Rodrigues Pereira Ramos; Gomes, Maria Isabel; Barbosa-póvoa, Ana Paula (Resources, Conservation and Recycling, 2014)
Packaging waste collection systems are responsible to collect, within a geographic area, three types of packaging materials (paper, glass and plastic/metal) that are disposed by the final consumer into special bins. Those systems are often characterized by having a network with multiple depots that act as transfer and sorting stations, and where the vehicle fleet is based. However, each depot is often managed independently and not as a part of a unique system. In this work, four current tactical/operational practices that contribute to the independent management of each depot are analysed. The change of such practices is investigated and their impact assessed on the total collection cost. A solution methodology based on mathematical formulations is developed to plan service areas, vehicle routes and vehicle schedules taking into account new alternative solutions in managing the system as a whole. Such methodology is applied to a real case study of a company responsible for the collection of the packaging waste in 7 municipalities in mainland Portugal. New service areas, collection routes and vehicle schedules are defined and significant savings are obtained in terms of the total distance travelled as well as in terms of the number of required vehicles, resulting in a decreasing of the total system cost.
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Biochemical, Stabilization and Crystallization Studies on a Molecular Chaperone (PaoD) Involved in the Maturation of Molybdoenzymes. - Otelo-Cardoso, AR; Schwuchow, V; Rodrigues, D.; Cabrita, E. J.; Leimkühler, S; Romão, MJ; Santos-Silva, T (PLoS One, 2014)
Molybdenum and tungsten enzymes require specific chaperones for folding and cofactor insertion. PaoD is the chaperone of the periplasmic aldehyde oxidoreductase PaoABC. It is the last gene in the paoABCD operon in Escherichia coli and its presence is crucial for obtaining mature enzyme. PaoD is an unstable, 35 kDa, protein. Our biochemical studies showed that it is a dimer in solution with a tendency to form large aggregates, especially after freezing/thawing cycles. In order to improve stability, PaoD was thawed in the presence of two ionic liquids [C4mim]Cl and [C2OHmim]PF6 and no protein precipitation was observed. This allowed protein concentration and crystallization using polyethylene glycol or ammonium sulfate as precipitating agents. Saturation transfer difference – nuclear magnetic resonance (STD-NMR) experiments have also been performed in order to investigate the effect of the ionic liquids in the stabilization process, showing a clear interaction between the acidic ring protons of the cation and, most likely, negatively charged residues at the protein surface. DLS assays also show a reduction of the overall size of the protein aggregates in presence of ionic liquids. Furthermore, cofactor binding studies on PaoD showed that the protein is able to discriminate between molybdenum and tungsten bound to the molybdenum cofactor, since only a Mo-MPT form of the cofactor remained bound to PaoD.

Body ownership of virtual avatars: an affordance approach of telepresence - Coelho; T.; De Oliveira; R.; Cardoso; T.; Rosas; J.; Rybarczyk Y. (Innovative and Creative Developments in Multimodal Interaction Systems, 2014)

Body Ownership of Virtual Avatars: An affordance Approach of Telepresence - Rybarczyk, Yves; Cardoso, Tiago; Coelho, Tiago; Oliveira, Rita; Rosas, João (Enterface 2013 Proceedings, 2014)
Virtual environments are an increasing trend in today’s society. In this scope, the avatar is the representation of the user in the virtual world. However, that relationship lacks empirical studies regarding the nature of the interaction between avatars and human beings. For that purpose it was studied how the avatar’s modeled morphology and dynamics affect its control by the user. An experiment was conducted to measure telepresence and ownership on participants who used a Kinect Natural User Interface (NUI). The body ownership of different avatars was assessed through a behavioral parameter, based on the concept of affordances, and a questionnaire of presence. The results show that the feelings of telepresence and ownership seem to be greater when the kinematics and the avatar’s proportions are closer to those of the user.

The Cauchy singular integral operator on weighted variable Lebesgue spaces - Karlovich, Alexei Yu.; Spitkovsky, Ilya M. (Concrete Operators, Spectral Theory, Operators in Harmonic Analysis and Approximation. Operator Theory: Advances and Applications, 236, 2014)
Let \(p:\mathbb{R}\to(1,\infty)\) be a globally log-Hölder continuous variable exponent and \(w:\mathbb{R}\to[0,\infty]\) be a weight. We prove that the Cauchy singular integral operator \(S\) is bounded on the weighted variable Lebesgue space \(L^{p(\cdot)}(\mathbb{R},w)=\{f:fw\in L^{p(\cdot)}(\mathbb{R})\}\) if and only if the weight \(w\) satisfies $$ \sup_{-\infty < a < b < \infty} \frac{1}{b-a} \|w\chi_{(a,b)}\|_{p(\cdot)} \|w^{-1}\chi_{(a,b)}\|_{p'(\cdot)}<\infty \quad (1/p(x)+1/p'(x)=1). $$

Consensos e dilemas no ensino de matemática a alunos de um curso de Decoração e Pintura Cerâmica - Rocha, H. (Atas do VI Seminário Luso-Brasileiro Educação, Trabalho e Movimentos Sociais, 2014)
A Matemática é uma das áreas que integra o plano curricular dos Cursos de Educação e Formação (CEF), pelo contributo para o exercício da cidadania em sociedades democráticas e tecnologicamente avançadas, mas esta é, também, frequentemente fonte de exclusão. O programa reconhece-o e enfatiza uma aprendizagem mais ligada ao concreto e à realidade. Mas reconhece também que é ao professor que compete gerir a sua implementação, dando forma às situações de aprendizagem e integrando-as de forma coerente e articulada no curso específico que os alunos frequentam. O estudo que aqui se apresenta teve como principal objectivo analisar e compreender as opções efectuadas pelo professor no decorrer das diferentes etapas da sua prática, dando atenção aos dilemas que enfrentou e às razões que valorizou na tomada de decisões. A abordagem metodológica adoptada é de natureza qualitativa e interpretativa, com a realização dum estudo de caso do professor de Matemática Aplicada dum CEF de Decoração e Pintura Cerâmica. A recolha de dados foi concretizada através de entrevistas, observação de aulas e recolha documental, sendo a análise de dados orientada pelo quadro teórico, conciliado com a interpretação destes. Nas conclusões do estudo a redução dos pré-requisitos, a preocupação em partir dos interesses dos alunos e a intenção de alargar a cultura dos alunos surgem como centrais na selecção das tarefas; enquanto o envolvimento activo dos alunos caracteriza a implementação das aulas. Os dilemas centram-se fundamentalmente na valorização relativa e aprofundamento a atribuir a cada conteúdo e na articulação entre formal e intuitivo.

The Cramér-Lundberg and the dual risk models: Ruin, dividend problems and duality features - Bergel, A.; Cardoso, R. M. R.; Egídio dos Reis, A.D.; Rodríguez-Martínez, E.V (ICA 2014, the 30th International Congress of Actuaries, 2014)

Crocodylomorph eggs and eggshells from the Lourinhã Fm. (Upper Jurassic), Portugal - Russo, J.; O. Mateus; Balbino, A.; Marzola, M. (Comunicações Geológicas, 2014)
We here present fossil Crocodylomorpha eggshells from the Upper Jurassic Lourinhã Formation of Portugal, recovered from five sites: one nest from Cambelas with 13 eggs, and three partial eggs and various fragments from, Paimogo N (I), Paimogo S (II), Casal da Rola, and Peralta. All specimens but the nest were found in association with dinosaur egg material. Our research reveals that on a micro- and ultrastructural analysis, all samples present the typical characters consistent with crocodiloid eggshell morphotype, such as the shell unit shape, the organization of the eggshell layers, and the triangular blocky extinction observed with crossed nicols. We assign the material from the Lourinhã Formation to the oofamily Krokolithidae, making it the oldest crocodylomorph eggs known so far, as well as the best record for eggs of non- crocodylian crocodylomorphs. Furthermore, our study indicates that the basic structure of crocodiloid eggshells has remained stable since at least the Upper Jurassic.

Crystallization and microstructure of Eu3+-doped lithium aluminophosphate glass - Roque S. Soares , Regina C.C. Monteiro, Andreia A.S. Lopes, Maria M.R.A. Lima, Bogdan A. Sava, Mihail Elisa (Journal of Non-Crystalline Solids, 2014)

Design of net zero energy buildings: Feedback from international projects - Garde, F; Lenoir, A; Scognamiglio, A.; Aelenei, D.; Waldren, D; Rostvik, HN; Ayoub, J; Aelenei, L.; Donn, M; Tardif, M; others (Energy Procedia, 2014)
The International Energy Agency (IEA), through the Solar Heating and Cooling programme (SHC) Task 40 and the Energy Conservation in Buildings and Community Systems programme (ECBCS, now named EBC) Annex 52, works towards developing a common understanding and setting up the basis for an international definition framework for Net Zero Energy Buildings (Net ZEBs). One of the subtasks of this programme?SubTaskC focuses benchmarking the Net ZEBs around the world to identify the innovative solutions sets that makes up this new type of building. This paper presents an overview of the work conducted by the participants of Subtask C and of Zero Energy Building projects that have been identified.
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Keywords: case studies; Design strategies; Net-ZEBs; solution sets

Development of a wearable monitoring system for service dogs - Seabra; J.; Rybarczyk; Y.; Batista; A.; Rybarczyk; P.; Lebret; M.C.; Vernay D. (IEEE Roman’14, Workshop on Wearable Technology and Human-Wearable Robot Interaction, 2014)

Development of a Wearable Monitoring System for Service Dogs - Seabra , J; Rybarcsik, Y; Batista, A (IEEE Roman WorkShop, 2014)

Development of an Ambient Assisted Living - Rosas, João; Carvalho, Gonçalo; Rybarczyk, Yves; Cardoso, Tiago (Enterface 2013 Proceedings, 2014)

Different representations in mathematics teaching with technology - Rocha, H. (Proceedings of the 38th Conference of the International Group for the Psychology of Mathematics Education, 2014)
The main focus of this paper is the teacher’s representational fluency in a context of graphing calculator use. The conclusions reached point to a more intensive use of some representations over the others, suggesting that technology turns numerical or tabular representation into two different representations.