%0 Journal Article %J Angewandte Chemie International Edition %D 2012 %T Biocompatible Polyurea Dendrimers with pH-Dependent Fluorescence %A Restani, Rita B. %A Morgado, Patrícia I. %A Ribeiro, Maximiano P. %A Correia, Ilídio J. %A Aguiar-Ricardo, Ana %A Bonifácio, Vasco D. B. %I WILEY-VCH Verlag %K cytotoxicity %K dendrimers %K fluorescence %K supercritical carbon dioxide %P 5162–5165 %R 10.1002/anie.201200362 %U http://dx.doi.org/10.1002/anie.201200362 %V 51 %X

Biocompatible and biodegradable water-soluble dendrimers comprising ureas within the interior and amino groups on the periphery were synthesized in supercritical carbon dioxide (dendrimer of generation 1 shown in picture). This novel class of dendrimers shows a pH-dependent intrinsic blue fluorescence at very low concentrations, which makes them potential polymeric fluorescent cell markers.

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