Márcia Tavares
mt.tavares@campus.fct.unl.pt
in
2009-2012: BSc in Biochemistry, New University of Lisbon
Composite particles for pulmonary delivery
Recenty, the pulmonary route has attracted attention as a noninvasive route to drug delivery, since it facilitates a site specific treatment of lung diseases with lower systemic exposure. Dry powders using biodegradable and biocompatible materials have been investigated as carriers for delivery of pharmaceutical compounds to the deep lung.
In this work, micron-sized PLGA particles are produced by Supercritical Assisted Atomization (SAA) - the use of this technology will allow the development of specific pharmaceutical formulations containing a model protein, BSA, and drugs to treat diseases associated with the lungs, such as cystic fibrosis and pulmonary hypertension.