%0 Journal Article %J BIOSENSORS & BIOELECTRONICS %D 2010 %T Ultrasensitive microchip sensor based on boron-containing polyfluorene nanofilms %A Ribeiro, Celso %A Brogueira, Pedro %A Lavareda, Guilherme %A de Carvalho, Carlos Nunes %A Amaral, Ana %A Santos, Luis %A Morgado, Jorge %A Scherf, Ulrich %A Bonifacio, Vasco D. B. %P 1662-1665 %R 10.1016/j.bios.2010.08.077 %V 26 %X

A fluorene-based pi-conjugated copolymer with on-chain dibenzoborole units was used in the development of a nanocoated gold interdigitated microelectrode array device which successfully detects fluoride in a broad range of concentrations (10(-11)-10(-4) M) in aqueous solution, upon impedance spectroscopy measurements. A calibration curve obtained over this range of concentrations and a new analytical method based on impedance spectroscopy measurements in aqueous solution is proposed. The sensor nanofilm was produced by spin-coating and diagnosed via spectroscopic ellipsometry, AFM, and electrically conductivity techniques. Changes in the conductivity due to the boron-fluoride complex formation seem to be the major mechanism behind the dependence of impedimetric results on the fluoride concentration. (C) 2010 Elsevier B.V. All rights reserved.

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World Congress on Biosensors, Glasgow, SCOTLAND, MAY 26-28, 2010

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